STW chemical sensors

A new kind of chemical sensor which is based on the surface transverse wave (STW) delay line is reported. This sensor is ideally suited to measurements of surface-attached mass under fluid immersion, and it is demonstrated operating under these conditions at 250 MHz. The mass sensitivity of an STW sensor is approximately 10 times greater than that of a thickness shear mode (TSM) or shear horizontal acoustic plate mode (SH-APM) sensor. The sensitivity is roughly comparable to that of a flexural plate wave (FPW) sensor, but it does suffer from the FPW sensor's fragility. The STW device is applied to biosensing. By directly immobilizing antibodies on the surface, the sensor is used to detect human immunoglobulin G at a level of 33 nanomoles/liter.<<ETX>>

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