LongQt: A cardiac electrophysiology simulation platform

Graphical abstract

[1]  Sathya D. Unudurthi,et al.  Two‐Pore K+ Channel TREK‐1 Regulates Sinoatrial Node Membrane Excitability , 2016, Journal of the American Heart Association.

[2]  Mark E. Anderson,et al.  Oxidized Calmodulin Kinase II Regulates Conduction Following Myocardial Infarction: A Computational Analysis , 2009, PLoS Comput. Biol..

[3]  E. Sobie Parameter sensitivity analysis in electrophysiological models using multivariable regression. , 2009, Biophysical journal.

[4]  M. Courtemanche,et al.  Ionic mechanisms underlying human atrial action potential properties: insights from a mathematical model. , 1998, The American journal of physiology.

[5]  G. Bett,et al.  Computer model of action potential of mouse ventricular myocytes. , 2004, American journal of physiology. Heart and circulatory physiology.

[6]  Y Rudy,et al.  Ionic charge conservation and long-term steady state in the Luo-Rudy dynamic cell model. , 2001, Biophysical journal.

[7]  Yoram Rudy,et al.  Simulation of the Undiseased Human Cardiac Ventricular Action Potential: Model Formulation and Experimental Validation , 2011, PLoS Comput. Biol..

[8]  Thomas J. Hund,et al.  Cycle Length Restitution in Sinoatrial Node Cells: A Theory for Understanding Spontaneous Action Potential Dynamics , 2014, PloS one.

[9]  Yoram Rudy,et al.  Rate Dependence and Regulation of Action Potential and Calcium Transient in a Canine Cardiac Ventricular Cell Model , 2004, Circulation.

[10]  Denis Noble,et al.  The Cardiac Physiome: perspectives for the future , 2009, Experimental physiology.

[11]  Mark E. Anderson,et al.  Atrial fibrillation and sinus node dysfunction in human ankyrin-B syndrome: a computational analysis. , 2013, American journal of physiology. Heart and circulatory physiology.

[12]  Rodrigo Weber dos Santos,et al.  CellML and associated tools and techniques , 2008, Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences.

[13]  Henggui Zhang,et al.  A mathematical model of action potentials of mouse sinoatrial node cells with molecular bases , 2011, American journal of physiology. Heart and circulatory physiology.

[14]  Ronald W. Joyner,et al.  Simulation of Action Potential Propagation in an Inhomogeneous Sheet of Coupled Excitable Cells , 1975, Circulation research.

[15]  J. Jalife,et al.  Human Atrial Action Potential and Ca2+ Model: Sinus Rhythm and Chronic Atrial Fibrillation , 2011, Circulation research.

[16]  Yoram Rudy,et al.  Role of activated CaMKII in abnormal calcium homeostasis and I(Na) remodeling after myocardial infarction: insights from mathematical modeling. , 2008, Journal of molecular and cellular cardiology.

[17]  Yasutaka Kurata,et al.  Dynamical description of sinoatrial node pacemaking: improved mathematical model for primary pacemaker cell. , 2002, American journal of physiology. Heart and circulatory physiology.

[18]  Michael Clerx,et al.  Myokit: A simple interface to cardiac cellular electrophysiology. , 2016, Progress in biophysics and molecular biology.

[19]  Catherine M Lloyd,et al.  CellML: its future, present and past. , 2004, Progress in biophysics and molecular biology.

[20]  Peter J. Hunter,et al.  OpenCOR: a modular and interoperable approach to computational biology , 2015, Front. Physiol..

[21]  Yoram Rudy,et al.  Computational biology in the study of cardiac ion channels and cell electrophysiology , 2006, Quarterly Reviews of Biophysics.

[22]  Sathya D. Unudurthi,et al.  Mathematical modeling of physiological systems: an essential tool for discovery. , 2014, Life sciences.

[23]  D. Noble,et al.  A model for human ventricular tissue. , 2004, American journal of physiology. Heart and circulatory physiology.