A polymethoxyflavone from Laggera pterodonta induces apoptosis in imatinib-resistant K562R cells via activation of the intrinsic apoptosis pathway

[1]  Franziska Michor,et al.  Dynamics of chronic myeloid leukemia response to dasatinib, nilotinib, and high-dose imatinib , 2014, Haematologica.

[2]  Yuezhou Chen,et al.  Antitumor effect of traditional Chinese herbal medicines against lung cancer , 2014, Anti-cancer drugs.

[3]  Xiaoyan Jiang,et al.  Selective JAK2/ABL dual inhibition therapy effectively eliminates TKI-insensitive CML stem/progenitor cells , 2014, Oncotarget.

[4]  Chi-Tang Ho,et al.  Pro-Apoptotic Effects of the Novel Tangeretin Derivate 5-Acetyl-6,7,8,4′-Tetramethylnortangeretin on MCF-7 Breast Cancer Cells , 2014, Cell Biochemistry and Biophysics.

[5]  S. Okabe,et al.  Combination of the ABL kinase inhibitor imatinib with the Janus kinase 2 inhibitor TG101348 for targeting residual BCR-ABL-positive cells , 2014, Journal of Hematology & Oncology.

[6]  J. Shi,et al.  Tangeretin, a citrus polymethoxyflavonoid, induces apoptosis of human gastric cancer AGS cells through extrinsic and intrinsic signaling pathways. , 2014, Oncology reports.

[7]  Chun Xing Li,et al.  Compounds from Chinese herbal medicines as reversal agents for P-glycoprotein-mediated multidrug resistance in tumours , 2014, Clinical and Translational Oncology.

[8]  F. Greco,et al.  Flavonoids as prospective compounds for anti-cancer therapy. , 2013, The international journal of biochemistry & cell biology.

[9]  Min-Ah Park,et al.  Anticancer effect of genistein on BG-1 ovarian cancer growth induced by 17 β-estradiol or bisphenol A via the suppression of the crosstalk between estrogen receptor α and insulin-like growth factor-1 receptor signaling pathways. , 2013, Toxicology and applied pharmacology.

[10]  B. Zhao,et al.  Gallic acid reduces cell viability, proliferation, invasion and angiogenesis in human cervical cancer cells , 2013, Oncology letters.

[11]  Shaohua Chen,et al.  Proliferation inhibition and apoptosis induction of imatinib-resistant chronic myeloid leukemia cells via PPP2R5C down-regulation , 2013, Journal of Hematology & Oncology.

[12]  Yamei Chen,et al.  Ibrutinib and novel BTK inhibitors in clinical development , 2013, Journal of Hematology & Oncology.

[13]  J. Melo,et al.  Safety and efficacy of imatinib cessation for CML patients with stable undetectable minimal residual disease: results from the TWISTER study. , 2013, Blood.

[14]  H. Kantarjian,et al.  Management of imatinib-resistant patients with chronic myeloid leukemia , 2013, Therapeutic advances in hematology.

[15]  N. Hawkins,et al.  The relative efficacy of imatinib, dasatinib and nilotinib for newly diagnosed chronic myeloid leukemia: a systematic review and network meta-analysis , 2013, Experimental Hematology & Oncology.

[16]  K. Döhner,et al.  Quizartinib (AC220) is a potent second generation class III tyrosine kinase inhibitor that displays a distinct inhibition profile against mutant-FLT3, -PDGFRA and -KIT isoforms , 2013, Molecular Cancer.

[17]  Chuanfeng Wu,et al.  Targeting of AML1-ETO in t(8;21) Leukemia by Oridonin Generates a Tumor Suppressor–Like Protein , 2012, Science Translational Medicine.

[18]  Hong Yang,et al.  Vitexicarpin induces apoptosis in human prostate carcinoma PC-3 cells through G2/M phase arrest. , 2012, Asian Pacific journal of cancer prevention : APJCP.

[19]  Hong-jun Hao,et al.  [Effects of quercetin on multidrug resistance and expression of related genes in human erythroleukemic K562/a cells]. , 2011, Zhongguo shi yan xue ye xue za zhi.

[20]  Cao Chang 3,5-Hydroxy-6,7,3′,4′-tetramethoxyflavone Isolated From Laggera pterodonta Induces CNE Cell Apoptosis , 2011 .

[21]  S. Kuntz,et al.  Title: Chrysin Blocks Topotecan-induced Apoptosis in Caco-2 Cells in Spite of Inhibition of Abc-transporters Chrysin Blocks Topotecan-induced Apoptosis in Caco-2 Cells in Spite of Inhibition of Abc-transporters , 2022 .

[22]  W. Ye,et al.  [Chemical constituents of Laggera pterodonta]. , 2010, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

[23]  S. Chattopadhyay,et al.  Aqueous Cinnamon Extract (ACE-c) from the bark of Cinnamomum cassia causes apoptosis in human cervical cancer cell line (SiHa) through loss of mitochondrial membrane potential , 2010, BMC Cancer.

[24]  Ming Yan,et al.  Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo. , 2007, Blood.

[25]  Han-Dong Sun,et al.  [Research progress in Laggera medicinal plants]. , 2006, Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.

[26]  J. Melo,et al.  Chronic myeloid leukemia--advances in biology and new approaches to treatment. , 2003, The New England journal of medicine.

[27]  H. Wajant,et al.  The Fas Signaling Pathway: More Than a Paradigm , 2002, Science.

[28]  X. Liu,et al.  An APAF-1·Cytochrome c Multimeric Complex Is a Functional Apoptosome That Activates Procaspase-9* , 1999, The Journal of Biological Chemistry.

[29]  N. Heisterkamp,et al.  Evidence that the phl gene encodes a 160,000-dalton phosphoprotein with associated kinase activity. , 1987, Molecular and cellular biology.