Correlation Between Electrical Bioimpedance and Pressure Waveform in Radial Artery and in Mechanical Pulsating Pipe System

The approach of comparing the effect of externally applied pressure onto radial artery in wrist and similarly also onto flexible pipe in artificial on-desk model of cardiovascular system on simultaneously measured electrical bioimpedance and pressure waveform is presented in this paper. Correlation between the measured impedance and simultaneous pressure waveforms in pipe of pulsating saline solution and the same measured parameters of pulsating blood in radial artery was performed. Results showed the correlation between the detected time varying impedance and pressure in artificial cardiovascular system – the presence of increasing trend appears while increasing the squeezing level of the pipe. The contrary result in the case of time varying impedance and pressure in radial artery reveal the complexity of the cardiovascular system of a man with its compensation mechanisms and possible targeting pathway through ulnar artery. However, the outcome also refers to notion of the source of impedance signal – the main contribution from the pulsating volume of blood can be expected. If the agreeable trend of time varying pressure denotes the effect of externally increased inherent pressure in the system and the comparability of developed artificial cardiovascular system, then the decreasing trend of time varying impedance of blood in radial artery refers to the need for modifications on the mechanical system. The convergency of time varying impedance of pulse wave above the externally applied pressure of weight 400 g was verified.

[1]  Ramakrishna Mukkamala,et al.  Robust pulse wave velocity estimation by application of system identification to proximal and distal arterial waveforms , 2010, 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology.

[2]  Bruce Cornish,et al.  Time frequency analysis of the experimental electrical impedance of pulsatile blood flowing through rigid tubes , 2009 .

[3]  Paul Annus,et al.  Bioimpedance sensing - a viable alternative for tonometry in non-invasive assessment of central aortic pressure , 2017, 2017 IEEE International Symposium on Medical Measurements and Applications (MeMeA).

[4]  Geoffrey G Hallock Recognition of potential morbidity after use of the radial artery as a conduit for coronary artery revascularization. , 2003, The Canadian journal of plastic surgery = Journal canadien de chirurgie plastique.

[5]  Mart Min,et al.  Electrode Optimization for Bioimpedance Based Central Aortic Blood Pressure Estimation , 2019 .

[6]  P. Huard,et al.  The Yellow Emperor's Classic of Internal Medicine , 1968, Medical History.

[7]  Paul Annus,et al.  Availability and variations of cardiac activity in the case of measuring the bioimpedance of wrist , 2018, 2018 IEEE International Instrumentation and Measurement Technology Conference (I2MTC).

[8]  A. Tajik,et al.  Noninvasive measurement of central vascular pressures with arterial tonometry: clinical revival of the pulse pressure waveform? , 2010, Mayo Clinic proceedings.

[9]  Robert P Patterson,et al.  Impedance cardiography: What is the source of the signal? , 2010 .

[10]  M. S. Sadove,et al.  Correlation Between Arterial Blood Pressure Levels and (dZ/dt)min in Impedance Plethysmography , 1985, IEEE Transactions on Biomedical Engineering.

[11]  Rob M. Heethaar,et al.  On the flow dependency of the electrical conductivity of blood , 2004, IEEE Transactions on Biomedical Engineering.