Detection of cytokeratin-19 mRNA-positive cells in the peripheral blood and bone marrow of patients with operable breast cancer

[1]  D. Mavroudis,et al.  Cytokeratin-19 mRNA-positive circulating tumor cells after adjuvant chemotherapy in patients with early breast cancer. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[2]  R C Coombes,et al.  Comparison of bone marrow, disseminated tumour cells and blood-circulating tumour cells in breast cancer patients after primary treatment , 2008, British Journal of Cancer.

[3]  M. Beckmann,et al.  Prognostic relevance of circulating tumor cells (CTCs) in peripheral blood of breast cancer patients before and after adjuvant chemotherapy: The German SUCCESS-Trial , 2008 .

[4]  C. Sotiriou,et al.  Different prognostic value of cytokeratin-19 mRNA positive circulating tumor cells according to estrogen receptor and HER2 status in early-stage breast cancer. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[5]  D. Mavroudis,et al.  Clinical relevance of circulating CK-19 mRNA-positive cells detected during the adjuvant tamoxifen treatment in patients with early breast cancer. , 2007, Annals of oncology : official journal of the European Society for Medical Oncology.

[6]  I. Zuna,et al.  Improved overall survival in postmenopausal women with early breast cancer after anastrozole initiated after treatment with tamoxifen compared with continued tamoxifen: the ARNO 95 Study. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[7]  V. Georgoulias,et al.  Clinical relevance of circulating CK-19 mRNA-positive cells detected during the period of adjuvant tamoxifen treatment in patients with early breast cancer , 2007 .

[8]  M. Rezai,et al.  Circulating tumor cells (CTCs) in peripheral blood of primary breast cancer patients , 2007 .

[9]  P. Lønning,et al.  Survival and safety of exemestane versus tamoxifen after 2–3 years' tamoxifen treatment (Intergroup Exemestane Study): a randomised controlled trial , 2007, The Lancet.

[10]  D. Mavroudis,et al.  Predictive and prognostic value of peripheral blood cytokeratin-19 mRNA-positive cells detected by real-time polymerase chain reaction in node-negative breast cancer patients. , 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[11]  J. Nesland,et al.  Comparison of the clinical significance of occult tumor cells in blood and bone marrow in breast cancer , 2006, International journal of cancer.

[12]  E. van Marck,et al.  Real-time RT–PCR detection of disseminated tumour cells in bone marrow has superior prognostic significance in comparison with circulating tumour cells in patients with breast cancer , 2006, British Journal of Cancer.

[13]  W. Sauerbrei,et al.  Reporting recommendations for tumor marker prognostic studies (REMARK). , 2005, Journal of the National Cancer Institute.

[14]  Thomas Rau,et al.  Circulating Tumor Cells in Breast Cancer: Correlation to Bone Marrow Micrometastases, Heterogeneous Response to Systemic Therapy and Low Proliferative Activity , 2005, Clinical Cancer Research.

[15]  Y Wang,et al.  Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials , 2005, The Lancet.

[16]  Bjørn Naume,et al.  Circulating and disseminated tumor cells. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[17]  S. Braun,et al.  The persistence of isolated tumor cells in bone marrow from patients with breast carcinoma predicts an increased risk for recurrence , 2005, Cancer.

[18]  M. Perraki,et al.  Detection of CK-19 mRNA-positive cells in the peripheral blood of breast cancer patients with histologically and immunohistochemically negative axillary lymph nodes. , 2005, Annals of oncology : official journal of the European Society for Medical Oncology.

[19]  Alison Stopeck,et al.  Circulating tumor cells, disease progression, and survival in metastatic breast cancer. , 2004, The New England journal of medicine.

[20]  J. Nesland,et al.  Isolated Tumor Cells in Bone Marrow Three Years after Diagnosis in Disease-Free Breast Cancer Patients Predict Unfavorable Clinical Outcome1 , 2004, Clinical Cancer Research.

[21]  Anne Vincent-Salomon,et al.  Clinical Significance of Immunocytochemical Detection of Tumor Cells Using Digital Microscopy in Peripheral Blood and Bone Marrow of Breast Cancer Patients , 2004, Clinical Cancer Research.

[22]  D. Mavroudis,et al.  Assessment of highly angiogenic and disseminated in the peripheral blood disease in breast cancer patients predicts for resistance to adjuvant chemotherapy and early relapse , 2004, International journal of cancer.

[23]  R. Paridaens,et al.  Detection of Micrometastatic Disease and Monitoring of Perioperative Tumor Cell Dissemination in Primary Operable Breast Cancer Patients Using Real-Time Quantitative Reverse Transcription-PCR , 2004, Clinical Cancer Research.

[24]  D. Mavroudis,et al.  Real-time quantification of CK-19 mRNA-positive cells in peripheral blood of breast cancer patients using the lightcycler system. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.

[25]  G Kvalheim,et al.  Detection of isolated tumor cells in bone marrow is an independent prognostic factor in breast cancer. , 2003, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[26]  I. Vlachonikolis,et al.  Peripheral blood circulating cytokeratin-19 mRNA-positive cells after the completion of adjuvant chemotherapy in patients with operable breast cancer. , 2003, Annals of oncology : official journal of the European Society for Medical Oncology.

[27]  D. Purdie.  Statistical Methods in Medical Research, 4th edn , 2003 .

[28]  I. Vlachonikolis,et al.  Molecular detection of cytokeratin-19-positive cells in the peripheral blood of patients with operable breast cancer: evaluation of their prognostic significance. , 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[29]  James N Ingle,et al.  Detection of circulating cytokeratin-positive cells in the blood of breast cancer patients using immunomagnetic enrichment and digital microscopy. , 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

[30]  T. Dimpfl,et al.  Cytokeratin-positive cells in the bone marrow and survival of patients with stage I, II, or III breast cancer. , 2000, The New England journal of medicine.

[31]  H Sommer,et al.  Lack of effect of adjuvant chemotherapy on the elimination of single dormant tumor cells in bone marrow of high-risk breast cancer patients. , 2000, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[32]  R. Coombes,et al.  Outcome of primary-breast-cancer patients with micrometastases: a long-term follow-up study , 1999, The Lancet.

[33]  R. Cote,et al.  Detection and clinical importance of micrometastatic disease. , 1999, Journal of the National Cancer Institute.

[34]  R C Coombes,et al.  Quantitative polymerase chain reaction for the detection of micrometastases in patients with breast cancer. , 1999, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[35]  Mike Clarke,et al.  Polychemotherapy for early breast cancer: an overview of the randomised trials , 1998, The Lancet.

[36]  M. Fan,et al.  Lymph node micrometastases from breast carcinoma , 1997, Cancer.

[37]  R. Coombes,et al.  The detection of micrometastases in the peripheral blood and bone marrow of patients with breast cancer using immunohistochemistry and reverse transcriptase polymerase chain reaction for keratin 19. , 1997, European journal of cancer.

[38]  J. Izbicki,et al.  Differential expression of proliferation-associated molecules in individual micrometastatic carcinoma cells. , 1993, Journal of the National Cancer Institute.

[39]  D. Collett.  Modelling Binary Data , 1991 .

[40]  Douglas G. Altman,et al.  Practical statistics for medical research , 1990 .

[41]  D. Cox,et al.  The analysis of binary data , 1971 .