The Cancer Biomedical Informatics Grid (caBIG‚): An Evolving Community for Cancer Research

This chapter describes the Cancer Biomedical Informatics Grid (caBIG®) project, a collaboration among the National Cancer Institute (NCI) and numerous discovery organizations, mostly NCI-designated cancer centers. The rationale for the caBIG® project opens the review, followed by description and analysis of the pilot phase (2004–2007). Changes in caBIG® as it transitions to an enterprise phase are evaluated. The chapter concludes with a review of important papers that either describe caBIG® components or are based on the initiative.

[1]  Joel H. Saltz,et al.  caGrid: design and implementation of the core architecture of the cancer biomedical informatics grid , 2006, Bioinform..

[2]  Kenneth H Buetow,et al.  An infrastructure for interconnecting research institutions. , 2009, Drug discovery today.

[3]  S. Hanash,et al.  Integrated global profiling of cancer , 2004, Nature Reviews Cancer.

[4]  Christopher G. Chute,et al.  caBIG™ Compatibility Review System: Software to Support the Evaluation of Applications Using Defined Interoperability Criteria , 2008, AMIA.

[5]  Rebecca S. Crowley,et al.  The CAP cancer protocols – a case study of caCORE based data standards implementation to integrate with the Cancer Biomedical Informatics Grid , 2006, BMC Medical Informatics Decis. Mak..

[6]  Julie Evans,et al.  Model Formulation: The BRIDG Project: A Technical Report , 2008, J. Am. Medical Informatics Assoc..

[7]  Mansur R. Kabuka,et al.  Model Formulation: semCDI: A Query Formulation for Semantic Data Integration in caBIG , 2008, J. Am. Medical Informatics Assoc..

[8]  Jianhua Xuan,et al.  Phenotypic-Specific Gene Module Discovery using a Diagnostic Tree and caBIGTM VISDA , 2006, 2006 International Conference of the IEEE Engineering in Medicine and Biology Society.

[9]  Olga Tchuvatkina,et al.  Proteomics LIMS: A caBIG™ Project, Year 1 , 2006, AMIA.

[10]  Patrick McConnell,et al.  The cancer translational research informatics platform , 2008, BMC Medical Informatics Decis. Mak..

[11]  Lewis J. Frey,et al.  Metadata mapping and reuse in caBIG™ , 2009, BMC Bioinformatics.

[12]  Taoying Huang,et al.  Development of the Lymphoma Enterprise Architecture Database: A caBIG(tm) Silver level compliant System , 2009, Cancer informatics.

[13]  Olivier Bodenreider,et al.  The caBIG terminology review process , 2009, J. Biomed. Informatics.

[14]  J. Kaiser.  Von Eschenbach Revises the NCI Agenda , 2004, Science.

[15]  Daniel L. Rubin,et al.  The caBIG™ Annotation and Image Markup Project , 2009, Journal of Digital Imaging.

[16]  Joel H. Saltz,et al.  The Cancer Biomedical Informatics Grid (caBIG™) Security Infrastructure , 2007, AMIA.

[17]  Frank J. Manion,et al.  Security and privacy requirements for a multi-institutional cancer research data grid: an interview-based study , 2009, BMC Medical Informatics Decis. Mak..

[18]  Bradley J. Erickson,et al.  Open Source Software Projects of the caBIG™ In Vivo Imaging Workspace Software Special Interest Group , 2007, Journal of Digital Imaging.

[19]  Subha Madhavan,et al.  Rembrandt: Helping Personalized Medicine Become a Reality through Integrative Translational Research , 2009, Molecular Cancer Research.

[20]  Joshua Phillips,et al.  The caCORE Software Development Kit: Streamlining construction of interoperable biomedical information services , 2006, BMC Medical Informatics Decis. Mak..

[21]  Tony Pan,et al.  GridIMAGE: A Novel Use of Grid Computing to Support Interactive Human and Computer-Assisted Detection Decision Support , 2007, Journal of Digital Imaging.

[22]  K. Buetow.  Cyberinfrastructure: Empowering a "Third Way" in Biomedical Research , 2005, Science.

[23]  JRobert Beck,et al.  The Cancer Biomedical Informatics Grid (caBIG): infrastructure and applications for a worldwide research community. , 2007, Studies in health technology and informatics.