Integrated approach to assess ecosystem health in harbor areas.

[1]  K. Schiff,et al.  Copper emissions from antifouling paint on recreational vessels. , 2004, Marine pollution bulletin.

[2]  J. Sturve,et al.  Oxidative damage in eelpout (Zoarces viviparus), measured as protein carbonyls and TBARS, as biomarkers. , 2005, Aquatic toxicology.

[3]  M. Bebianno,et al.  A multibiomarker approach in the clam Ruditapes decussatus to assess the impact of pollution in the Ria Formosa lagoon, South Coast of Portugal. , 2012, Marine environmental research.

[4]  N. C. Gomes,et al.  An ecotoxicological analysis of the sediment quality in a European Atlantic harbor emphasizes the current limitations of the Water Framework Directive. , 2013, Marine pollution bulletin.

[5]  Larraitz Garmendia,et al.  Marine ecosystem health status assessment through integrative biomarker indices: a comparative study after the Prestige oil spill “Mussel Watch” , 2013, Ecotoxicology.

[6]  N. Etxebarria,et al.  Combined use of native and caged mussels to assess biological effects of pollution through the integrative biomarker approach. , 2013, Aquatic toxicology.

[7]  M. Bebianno,et al.  A multibiomarker approach in Mytilus galloprovincialis to assess environmental quality. , 2009, Journal of environmental monitoring : JEM.

[8]  C. Annicchiarico,et al.  Predicting toxicity in marine sediment in Taranto Gulf (Ionian Sea, Southern Italy) using Sediment Quality Guidelines and a battery bioassay , 2007, Ecotoxicology.

[9]  L. Barillé,et al.  Temporal changes in nickel and vanadium concentrations and in condition index and metallothionein levels in three species of molluscs following the “Erika” oil spill , 2004 .

[10]  J. Svavarsson,et al.  Biochemical indicators of pollution exposure in shorthorn sculpin (Myoxocephalus scorpius), caught in four harbours on the southwest coast of Iceland. , 2000, Aquatic toxicology.

[11]  F. Piva,et al.  Environmental hazards from natural hydrocarbons seepage: integrated classification of risk from sediment chemistry, bioavailability and biomarkers responses in sentinel species. , 2014, Environmental pollution.

[12]  M. Bebianno,et al.  Occurrence of pharmaceutical compounds and pesticides in aquatic systems. , 2015, Marine pollution bulletin.

[13]  Manel Grifoll,et al.  A management system for accidental water pollution risk in a harbour: The Barcelona case study , 2011 .

[14]  F. Biandolino,et al.  Comparison of amphipods Corophium insidiosum and C. orientale (Crustacea: Amphipoda) in sediment toxicity testing , 2010, Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering.

[15]  B. H. Buck,et al.  Multi-biomarker approach using the blue mussel (Mytilus edulis L.) to assess the quality of marine environments: season and habitat-related impacts. , 2014, Marine environmental research.

[16]  Manfred Ehrhardt,et al.  Methods of seawater analysis , 1999 .

[17]  V. Quintino,et al.  Estuarine sediment acute toxicity testing with the European amphipod Corophium multisetosum Stock, 1952. , 2009, Chemosphere.

[18]  F. Onorati,et al.  A multidisciplinary weight of evidence approach for classifying polluted sediments: Integrating sediment chemistry, bioavailability, biomarkers responses and bioassays. , 2012, Environment international.

[19]  I. Erdelmeier,et al.  Reactions of N-methyl-2-phenylindole with malondialdehyde and 4-hydroxyalkenals. Mechanistic aspects of the colorimetric assay of lipid peroxidation. , 1998, Chemical research in toxicology.

[20]  M. Bebianno,et al.  Chemical residues and biochemical responses in wild and cultured European sea bass (Dicentrarchus labrax L.). , 2007, Environmental research.

[21]  M. Bebianno,et al.  Application of an integrated biomarker response index (IBR) to assess temporal variation of environmental quality in two Portuguese aquatic systems , 2012 .

[22]  V. Quintino,et al.  Acute toxicity testing with the European estuarine amphipod Corophium multisetosum , 2007, Hydrobiologia.

[23]  F. Martins,et al.  Integrated monitoring of South Portugal water bodies: a methodology towards WFD. , 2009, Water science and technology : a journal of the International Association on Water Pollution Research.

[24]  E. Long,et al.  Calculation and uses of mean sediment quality guideline quotients: a critical review. , 2006, Environmental science & technology.

[25]  J. Hellou,et al.  Stress on stress response of wild mussels, Mytilus edulis and Mytilus trossulus, as an indicator of ecosystem health. , 2003, Environmental pollution.

[26]  D. Fattorini,et al.  Contaminant accumulation and biomarker responses in caged mussels, Mytilus galloprovincialis, to evaluate bioavailability and toxicological effects of remobilized chemicals during dredging and disposal operations in harbour areas. , 2008, Aquatic toxicology.

[27]  F. Onorati,et al.  Assessing sediment hazard through a weight of evidence approach with bioindicator organisms: a practical model to elaborate data from sediment chemistry, bioavailability, biomarkers and ecotoxicological bioassays. , 2011, Chemosphere.

[28]  F. Gagné,et al.  Sex alteration in soft-shell clams (Mya arenaria) in an intertidal zone of the Saint Lawrence river (Quebec, Canada). , 2003, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.

[29]  R. Burk,et al.  Glutathione peroxidase activity in selenium-deficient rat liver. , 1976, Biochemical and biophysical research communications.

[30]  A. Volpi Ghirardini,et al.  Microtox solid phase test: Effect of diluent used in toxicity test. , 2009, Ecotoxicology and environmental safety.

[31]  R. Tauler,et al.  Characterization of the environmental quality of sediments from two estuarine systems based on different in-vitro bioassays. , 2014, Marine environmental research.

[32]  M. Bebianno,et al.  Glutathione S-tranferases and cytochrome P450 activities in Mytilus galloprovincialis from the South coast of Portugal: effect of abiotic factors. , 2007, Environment international.

[33]  M. Bebianno,et al.  Source and impact of lead contamination on δ-aminolevulinic acid dehydratase activity in several marine bivalve species along the Gulf of Cadiz. , 2011, Aquatic toxicology.

[34]  Katja Broeg,et al.  Indices for the assessment of environmental pollution of the Baltic Sea coasts: integrated assessment of a multi-biomarker approach. , 2006, Marine pollution bulletin.

[35]  A. D. Vethaak,et al.  Environmental impact and recovery at two dumping sites for dredged material in the North Sea. , 2003, Environmental pollution.

[36]  Fred D. Calder,et al.  Development and evaluation of sediment quality guidelines for Florida coastal waters , 1996, Ecotoxicology.

[37]  S. Giuliani,et al.  Application of biomarkers for assessing the biological impact of dredged materials in the Mediterranean: the relationship between antioxidant responses and susceptibility to oxidative stress in the red mullet (Mullus barbatus). , 2002, Marine pollution bulletin.

[38]  D. Pampanin,et al.  Physiological measurements from native and transplanted mussel (Mytilus galloprovincialis) in the canals of Venice. Survival in air and condition index. , 2005, Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.

[39]  S. Brooks,et al.  Integrated biomarker assessment of the effects exerted by treated produced water from an onshore natural gas processing plant in the North Sea on the mussel Mytilus edulis. , 2011, Marine pollution bulletin.

[40]  M. Bebianno,et al.  Chemical and biochemical tools to assess pollution exposure in cultured fish. , 2008, Environmental pollution.

[41]  A Viarengo,et al.  The use of biomarkers to assess the impact of pollution in coastal environments of the Iberian Peninsula: a practical approach. , 2000, The Science of the total environment.

[42]  S. Devin,et al.  The integrated biomarker response revisited: optimization to avoid misuse , 2014, Environmental Science and Pollution Research.

[43]  Other Directive 2000/60/EC of the European Parliament and of The Council of 23 October 2000 establishing a Framework for Community Action in the Field of Water Policy (Water Framework Directive) , 2000 .

[44]  M. Bebianno,et al.  Assessing pollutant exposure in cultured and wild sea bass (Dicentrarchus labrax) from the Iberian Peninsula , 2009, Ecotoxicology.

[45]  C. Bolognesi,et al.  DNA damage in eelpout (Zoarces viviparus) from Göteborg harbour. , 2004, Mutation research.

[46]  O. H. Lowry,et al.  Protein measurement with the Folin phenol reagent. , 1951, The Journal of biological chemistry.

[47]  R. Greenwald Handbook Methods For Oxygen Radical Research , 2017 .

[48]  T. Campisi,et al.  Ejercicio interlaboratorio de bioensayos marinos para la evaluación de la calidad ambiental desedimentos costeros en España. II. Ensayo de inhibición de la bioluminiscencia para la evaluación rápida de la toxicidad de sedimentos , 2006 .

[49]  J. Juanes,et al.  Methodological procedure for water quality management in port areas at the EU level , 2012 .

[50]  D. W. Thomas Handbook of Methods for Oxygen Radical Research , 1988, Journal of Pediatric Gastroenterology and Nutrition.

[51]  D. Fattorini,et al.  Time-course variations of oxyradical metabolism, DNA integrity and lysosomal stability in mussels, Mytilus galloprovincialis, during a field translocation experiment. , 2004, Aquatic toxicology.

[52]  A. Viarengo,et al.  The use of biomarkers in biomonitoring: a 2-tier approach assessing the level of pollutant-induced stress syndrome in sentinel organisms. , 2007, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.

[53]  Silvia Giuliani,et al.  A multidisciplinary weight of evidence approach for environmental risk assessment at the Costa Concordia wreck: Integrative indices from Mussel Watch. , 2014, Marine environmental research.

[54]  V. Dimitriadis,et al.  Assessment of the health status of mussels Mytilus galloprovincialis along Thermaikos Gulf (Northern Greece): an integrative biomarker approach using ecosystem health indices. , 2010, Ecotoxicology and environmental safety.

[55]  C. Mouneyrac,et al.  Assessment of the health status of Donax trunculus from the Gulf of Tunis using integrative biomarker indices , 2013 .

[56]  J. Sturve,et al.  Effects of dredging in göteborg harbor, sweden, assessed by biomarkers in eelpout (zoarces viviparus) , 2005, Environmental toxicology and chemistry.

[57]  Thierry Burgeot,et al.  Integrated biomarker response: A useful tool for ecological risk assessment , 2002, Environmental toxicology and chemistry.

[58]  E. Long,et al.  Development, Evaluation, and Application of Sediment Quality Targets for Assessing and Managing Contaminated Sediments in Tampa Bay, Florida , 2004, Archives of environmental contamination and toxicology.

[59]  K. Courtney,et al.  A new and rapid colorimetric determination of acetylcholinesterase activity. , 1961, Biochemical pharmacology.

[60]  H Journee,et al.  Survey on environmental monitoring requirements of European ports. , 2009, Journal of environmental management.

[61]  C. Lorenzen,et al.  DETERMINATION OF CHLOROPHYLL AND PHEO‐PIGMENTS: SPECTROPHOTOMETRIC EQUATIONS1 , 1967 .

[62]  Fred D. Calder,et al.  Incidence of adverse biological effects within ranges of chemical concentrations in marine and estuarine sediments , 1995 .

[63]  M. M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. , 1976, Analytical biochemistry.

[64]  P. J. Vuorinen,et al.  Biomarker responses in flounder (Platichthys flesus) and mussel (Mytilus edulis) in the Klaipeda-Būtinge area (Baltic Sea). , 2006, Marine pollution bulletin.

[65]  M. Bebianno,et al.  Interspecific variability of endocrine disruption and oxidative stress in two bivalve species from the Ria Formosa Lagoon (south coast of Portugal) , 2013 .

[66]  I. Fridovich,et al.  Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). , 1969, The Journal of biological chemistry.