Anti-infective potential of natural products: how to develop a stronger in vitro 'proof-of-concept'.

[1]  R. Pink,et al.  Opportunities and Challenges in Antiparasitic Drug Discovery , 2005, Nature Reviews Drug Discovery.

[2]  R. Verpoorte,et al.  Ethnopharmacology and systems biology: a perfect holistic match. , 2005, Journal of ethnopharmacology.

[3]  M. Recio,et al.  Medicinal plants and antimicrobial activity. , 2005, Journal of ethnopharmacology.

[4]  G. Cordell,et al.  Some thoughts on the future of ethnopharmacology. , 2005, Journal of ethnopharmacology.

[5]  B. Patwardhan.  Ethnopharmacology and drug discovery. , 2005, Journal of ethnopharmacology.

[6]  Ramanan Laxminarayan,et al.  Antimicrobial resistance in developing countries. Part I: recent trends and current status. , 2005, The Lancet. Infectious diseases.

[7]  C. Hart,et al.  Finding the target after screening the phenotype. , 2005, Drug discovery today.

[8]  F. Sams-Dodd.  Target-based drug discovery: is something wrong? , 2005, Drug discovery today.

[9]  Christopher T. Walsh,et al.  Lessons from natural molecules , 2004, Nature.

[10]  J. Bajorath,et al.  Docking and scoring in virtual screening for drug discovery: methods and applications , 2004, Nature Reviews Drug Discovery.

[11]  A. Verkman.  Drug discovery in academia. , 2004, American journal of physiology. Cell physiology.

[12]  P. Coley,et al.  A novel DNA-based microfluorimetric method to evaluate antimalarial drug activity. , 2004, The American journal of tropical medicine and hygiene.

[13]  A. Debrabant,et al.  Generation of Leishmania donovani axenic amastigotes: their growth and biological characteristics. , 2004, International journal for parasitology.

[14]  L. Maes,et al.  In Vitro and In Vivo Activities of a Triterpenoid Saponin Extract (PX-6518) from the Plant Maesa balansae against Visceral Leishmania Species , 2004, Antimicrobial Agents and Chemotherapy.

[15]  R. Doi,et al.  Indirect conductimetric assay of antibacterial activities , 2002, Journal of Industrial Microbiology and Biotechnology.

[16]  Fabio Zicker,et al.  Strategic emphases for tropical diseases research: a TDR perspective. , 2002, Trends in parasitology.

[17]  Jenny Gabrielson,et al.  Evaluation of redox indicators and the use of digital scanners and spectrophotometer for quantification of microbial growth in microplates. , 2002, Journal of microbiological methods.

[18]  M. Gillings,et al.  Potential problems with fluorescein diacetate assays of cell viability when testing natural products for antimicrobial activity. , 2001, Journal of microbiological methods.

[19]  N. Farnsworth,et al.  The value of plants used in traditional medicine for drug discovery. , 2001, Environmental health perspectives.

[20]  F. Haesebrouck,et al.  Influence of different medium components on the in vitro activity of the growth-promoting antibiotic flavomycin against enterococci. , 2000, The Journal of antimicrobial chemotherapy.

[21]  H. Greger,et al.  Testing of antifungal natural products: methodologies, comparability of results and assay choice , 2000 .

[22]  J. Eloff.  A Sensitive and Quick Microplate Method to Determine the Minimal Inhibitory Concentration of Plant Extracts for Bacteria , 1998, Planta medica.

[23]  B. Priem,et al.  Kinetic evaluation of conidial germination of Botrytis cinerea by a spectrofluorometric method , 1998 .

[24]  R. Kaminsky,et al.  The Alamar Blue assay to determine drug sensitivity of African trypanosomes (T.b. rhodesiense and T.b. gambiense) in vitro. , 1997, Acta tropica.

[25]  F. Buckner,et al.  Efficient technique for screening drugs for activity against Trypanosoma cruzi using parasites expressing beta-galactosidase , 1996, Antimicrobial agents and chemotherapy.

[26]  S. Bhakdi,et al.  Susceptibility testing of Candida albicans and Aspergillus species by a simple microtiter menadione-augmented 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide assay , 1995, Journal of clinical microbiology.

[27]  Michael Cole.  Key antifungal, antibacterial and anti-insect assays—a critical review , 1994 .

[28]  D. Veal,et al.  Rapid screening of the antimicrobial activity of extracts and natural products. , 1994, The Journal of antibiotics.

[29]  S. Colegate,et al.  Bioactive Natural Products Detection, Isolation, and Structural Determination , 1993 .

[30]  G. Cordell,et al.  Separation, structure elucidation, and bioassay of cytotoxic natural products , 1993 .

[31]  R. Piper,et al.  Parasite lactate dehydrogenase as an assay for Plasmodium falciparum drug sensitivity. , 1993, The American journal of tropical medicine and hygiene.

[32]  Kurt Hostettmann,et al.  A bioautographic agar overlay method for the detection of antifungal compounds from higher plants , 1991 .

[33]  A. Vlietinck,et al.  Can ethnopharmacology contribute to the development of antiviral drugs? , 1991, Journal of ethnopharmacology.

[34]  H Hirumi,et al.  Continuous cultivation of Trypanosoma brucei blood stream forms in a medium containing a low concentration of serum protein without feeder cell layers. , 1989, The Journal of parasitology.

[35]  M. Recio,et al.  Screening methods for natural products with antimicrobial activity: a review of the literature. , 1988, Journal of ethnopharmacology.

[36]  J. Haynes,et al.  Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique , 1979, Antimicrobial Agents and Chemotherapy.

[37]  A. Vlietinck,et al.  Screening of Higher Plants for Biological Activities I. Antimicrobial Activity , 1979, Planta medica.

[38]  W. Trager,et al.  Human malaria parasites in continuous culture. , 1976, Science.

[39]  L. Mitscher,et al.  Antimicrobial agents from higher plants. I. Introduction, rationale, and methodology. , 1972, Lloydia.

[40]  W. J. Powers,et al.  An improved resazurin-based cytotoxicity assay for hepatic cells , 2004, Cell Biology and Toxicology.

[41]  J. Oxford,et al.  Treatment of epidemic and pandemic influenza with neuraminidase and M2 proton channel inhibitors. , 2003, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

[42]  G. O’Toole,et al.  Mechanisms of biofilm resistance to antimicrobial agents. , 2001, Trends in microbiology.

[43]  R. Sidwell,et al.  Handbook of Animal Models of Infection , 1999 .

[44]  K. Hostettmann.  Methods in plant biochemistry: Volume 6. Assays for bioactivity. , 1991 .

[45]  G. Cordell,et al.  A direct bioautographic tlc assay for compounds possessing antibacterial activity. , 1987, Journal of natural products.

[46]  L. Mitscher.  Antimicrobial Agents from Higher Plants , 1975 .