PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia
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Michael P. Schroeder | H. Blum | P. Greif | A. Ekici | M. Schrappe | C. Eckert | J. Hecht | S. Hänzelmann | M. Horstmann | S. Krebs | M. Rieger | M. Neumann | A. R. James | T. Burmeister | C. Baldus | M. Brüggemann | N. Gökbuget | S. Schwartz | L. Bastian | S. Vosberg | C. Schlee | D. Wagner | Juan Lazaro-Navarro | Veronika Schulze | Sebastian Kämpf | Jutta Ortiz Tanchez | Konstandina Isaakidis
[1] A. Korobeynikov,et al. Sequence Analysis , 2020, Encyclopedia of Bioinformatics and Computational Biology.
[2] F. Sigaux,et al. PAX5 P80R mutation identifies a novel subtype of B-cell precursor acute lymphoblastic leukemia with favorable outcome. , 2019, Blood.
[3] Ashley D. Hill,et al. PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia , 2019, Nature Genetics.
[4] J. Stuchly,et al. Genomic landscape of pediatric B-other acute lymphoblastic leukemia in a consecutive European cohort , 2019, Haematologica.
[5] C. Pui,et al. Transcriptional landscape of B cell precursor acute lymphoblastic leukemia based on an international study of 1,223 cases , 2018, Proceedings of the National Academy of Sciences.
[6] Yunyu Zhang,et al. Constitutive Ras signaling and Ink4a/Arf inactivation cooperate during the development of B-ALL in mice. , 2017, Blood advances.
[7] M. Brüggemann,et al. Minimal residual disease in adult ALL: technical aspects and implications for correct clinical interpretation. , 2017, Blood advances.
[8] C. Mullighan,et al. Genetic Basis of Acute Lymphoblastic Leukemia. , 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[9] W. Hiddemann,et al. Adults with Philadelphia chromosome–like acute lymphoblastic leukemia frequently have IGH-CRLF2 and JAK2 mutations, persistence of minimal residual disease and poor prognosis , 2017, Haematologica.
[10] K. Okamura,et al. ZNF384-related fusion genes define a subgroup of childhood B-cell precursor acute lymphoblastic leukemia with a characteristic immunotype , 2017, Haematologica.
[11] T. Graeber,et al. Metabolic gatekeeper function of B-lymphoid transcription factors , 2016, Nature.
[12] Minoru Kanehisa,et al. KEGG: new perspectives on genomes, pathways, diseases and drugs , 2016, Nucleic Acids Res..
[13] Guido Marcucci,et al. Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia , 2016, Nature Communications.
[14] B. Johansson,et al. Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia , 2016, Nature Communications.
[15] L. McIntosh,et al. Structural and Dynamics Studies of Pax5 Reveal Asymmetry in Stability and DNA Binding by the Paired Domain. , 2016, Journal of molecular biology.
[16] O. Hofmann,et al. VarDict: a novel and versatile variant caller for next-generation sequencing in cancer research , 2016, Nucleic acids research.
[17] Eric Talevich,et al. CNVkit: Genome-Wide Copy Number Detection and Visualization from Targeted DNA Sequencing , 2016, PLoS Comput. Biol..
[18] Shinichi Morishita,et al. Recurrent DUX4 fusions in B cell acute lymphoblastic leukemia of adolescents and young adults , 2016, Nature Genetics.
[19] F. Cunningham,et al. The Ensembl Variant Effect Predictor , 2016, Genome Biology.
[20] J. Mesirov,et al. The Molecular Signatures Database Hallmark Gene Set Collection , 2015 .
[21] K. Goi,et al. Specific Antileukemic Activity of PD0332991, a CDK4/6 Inhibitor, against Philadelphia Chromosome–Positive Lymphoid Leukemia , 2015, Molecular Cancer Therapeutics.
[22] S. Constantinescu,et al. Infection Exposure is a Causal Factor in B-cell Precursor Acute Lymphoblastic Leukemia as a Result of Pax5-Inherited Susceptibility. , 2015, Cancer discovery.
[23] Bert Vogelstein,et al. The Path to Cancer --Three Strikes and You're Out. , 2015, The New England journal of medicine.
[24] J. Downing,et al. PAX5 is a tumor suppressor in mouse mutagenesis models of acute lymphoblastic leukemia. , 2015, Blood.
[25] Jos Jonkers,et al. CopywriteR: DNA copy number detection from off-target sequence data , 2015, Genome Biology.
[26] D. Adams,et al. CopywriteR: DNA copy number detection from off-target sequence data , 2015, Genome Biology.
[27] S. Salzberg,et al. StringTie enables improved reconstruction of a transcriptome from RNA-seq reads , 2015, Nature Biotechnology.
[28] Rolf Larsson,et al. DNA methylation-based subtype prediction for pediatric acute lymphoblastic leukemia , 2014, Clinical Epigenetics.
[29] C. Mullighan. The genomic landscape of acute lymphoblastic leukemia in children and young adults. , 2014, Hematology. American Society of Hematology. Education Program.
[30] O. Kallioniemi,et al. FusionCatcher – a tool for finding somatic fusion genes in paired-end RNA-sequencing data , 2014, bioRxiv.
[31] G. McVean,et al. Integrating mapping-, assembly- and haplotype-based approaches for calling variants in clinical sequencing applications , 2014, Nature Genetics.
[32] A. Borkhardt,et al. Inherited susceptibility to pre B-ALL caused by germline transmission of PAX5 c.547G>A , 2014, Leukemia.
[33] C. Eckert,et al. Ras pathway mutations are prevalent in relapsed childhood acute lymphoblastic leukemia and confer sensitivity to MEK inhibition. , 2013, Blood.
[34] Rohini Rau-Murthy,et al. A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia , 2013, Nature Genetics.
[35] M. Farrar,et al. Pax5 loss imposes a reversible differentiation block in B-progenitor acute lymphoblastic leukemia , 2013, Genes & development.
[36] A. Sivachenko,et al. Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples , 2013, Nature Biotechnology.
[37] Robert Huether,et al. The genomic landscape of hypodiploid acute lymphoblastic leukemia , 2013, Nature Genetics.
[38] E. Thiel,et al. Adult patients with acute lymphoblastic leukemia and molecular failure display a poor prognosis and are candidates for stem cell transplantation and targeted therapies. , 2012, Blood.
[39] Markus Jaritz,et al. The B‐cell identity factor Pax5 regulates distinct transcriptional programmes in early and late B lymphopoiesis , 2012, The EMBO journal.
[40] M. Farrar,et al. Ebf1 or Pax5 haploinsufficiency synergizes with STAT5 activation to initiate acute lymphoblastic leukemia , 2011, The Journal of experimental medicine.
[41] Nuria Lopez-Bigas,et al. Gitools: Analysis and Visualisation of Genomic Data Using Interactive Heat-Maps , 2011, PloS one.
[42] M. Muckenthaler,et al. Gain-of-function mutations in interleukin-7 receptor-α (IL7R) in childhood acute lymphoblastic leukemias , 2011, The Journal of experimental medicine.
[43] Süleyman Cenk Sahinalp,et al. deFuse: An Algorithm for Gene Fusion Discovery in Tumor RNA-Seq Data , 2011, PLoS Comput. Biol..
[44] B. Johansson,et al. The frequency and prognostic impact of dic(9;20)(p13.2;q11.2) in childhood B-cell precursor acute lymphoblastic leukemia: results from the NOPHO ALL-2000 trial , 2011, Leukemia.
[45] G. Weinstock,et al. VarScan: variant detection in massively parallel sequencing of individual and pooled samples , 2009, Bioinform..
[46] J. Downing,et al. Failure of CDKN2A/B (INK4A/B-ARF)-mediated tumor suppression and resistance to targeted therapy in acute lymphoblastic leukemia induced by BCR-ABL. , 2008, Genes & development.
[47] M. Busslinger,et al. Pax5: the guardian of B cell identity and function , 2007, Nature Immunology.
[48] Christopher B. Miller,et al. Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia , 2007, Nature.
[49] J. Mesirov,et al. From the Cover: Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles , 2005 .
[50] Mel Greaves,et al. Pre-natal origins of childhood leukemia. , 2003, Reviews in clinical and experimental hematology.
[51] G. Schaffner,et al. DNA sequence recognition by Pax proteins: bipartite structure of the paired domain and its binding site. , 1993, Genes & development.
[52] A. Knudson. Mutation and cancer: statistical study of retinoblastoma. , 1971, Proceedings of the National Academy of Sciences of the United States of America.