The Utility of Domain-Specific End Points in Acute Stroke Trials

[1]  A. Bonafe,et al.  Usefulness of a single-parameter tool for the prediction of large vessel occlusion in acute stroke , 2020, Journal of Neurology.

[2]  Bernd Weissmuller,et al.  Trials , 2020, Israelpolitik.

[3]  K. Sunnerhagen,et al.  Stroke survivors’ priorities for research related to life after stroke , 2020, Topics in stroke rehabilitation.

[4]  H. Chabriat,et al.  Refining endpoints for stroke recovery trials , 2020, The Lancet Neurology.

[5]  J. Saver,et al.  Mechanisms of action of acute and subacute sphenopalatine ganglion stimulation for ischemic stroke , 2020, International journal of stroke : official journal of the International Stroke Society.

[6]  S. Cramer.  Issues important to the design of stroke recovery trials , 2020, The Lancet Neurology.

[7]  M. Etherton,et al.  Redefining Normal: The Importance of White Matter Microstructural Integrity in Poststroke Outcomes. , 2020, Stroke.

[8]  L. Hochberg,et al.  Corticospinal Tract Injury Estimated From Acute Stroke Imaging Predicts Upper Extremity Motor Recovery After Stroke. , 2019, Stroke.

[9]  S. Liew,et al.  Stroke atlas of the brain: Voxel-wise density-based clustering of infarct lesions topographic distribution , 2019, NeuroImage: Clinical.

[10]  S. Kiran,et al.  Benchmarks of Significant Change After Aphasia Rehabilitation. , 2019, Archives of physical medicine and rehabilitation.

[11]  A. Demchuk,et al.  Resting-State Functional Connectivity Magnetic Resonance Imaging and Outcome After Acute Stroke , 2018, Stroke.

[12]  Heather B. Roesly.  Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging , 2018, The Journal of Emergency Medicine.

[13]  J. Baron.  Protecting the ischaemic penumbra as an adjunct to thrombectomy for acute stroke , 2018, Nature Reviews Neurology.

[14]  E. Lindsay.  Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct , 2018 .

[15]  C. Pantev,et al.  Randomized trial of transcranial direct current stimulation for poststroke dysphagia , 2018, Annals of neurology.

[16]  S. Cramer,et al.  Neuroimaging Identifies Patients Most Likely to Respond to a Restorative Stroke Therapy , 2018, Stroke.

[17]  Adam R Ferguson,et al.  Translational Stroke Research: Vision and Opportunities , 2017, Stroke.

[18]  Leonid Churilov,et al.  Standardized measurement of sensorimotor recovery in stroke trials: Consensus-based core recommendations from the Stroke Recovery and Rehabilitation Roundtable , 2017, International journal of stroke : official journal of the International Stroke Society.

[19]  Robert Leech,et al.  Domain-general subregions of the medial prefrontal cortex contribute to recovery of language after stroke , 2017, Brain : a journal of neurology.

[20]  A. Auchus,et al.  Safety and efficacy of multipotent adult progenitor cells in acute ischaemic stroke (MASTERS): a randomised, double-blind, placebo-controlled, phase 2 trial , 2017, The Lancet Neurology.

[21]  S. Payabvash,et al.  Cerebral regions preserved by successful endovascular recanalization of acute M1 segment occlusions: a voxel based analysis. , 2017, The British journal of radiology.

[22]  S. Cramer,et al.  Role of corpus callosum integrity in arm function differs based on motor severity after stroke , 2017, NeuroImage: Clinical.

[23]  S. Cramer,et al.  Proof-of-Concept Randomized Trial of the Monoclonal Antibody GSK249320 Versus Placebo in Stroke Patients , 2017, Stroke.

[24]  Brent J. Liu,et al.  Stroke Lesions in a Large Upper Limb Rehabilitation Trial Cohort Rarely Match Lesions in Common Preclinical Models , 2017, Neurorehabilitation and neural repair.

[25]  M. A. MacIver,et al.  Neuroscience Needs Behavior: Correcting a Reductionist Bias , 2017, Neuron.

[26]  J. Eng,et al.  Guidelines for Adult Stroke Rehabilitation and Recovery: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association , 2016, Stroke.

[27]  Lisa Cloonan,et al.  Role of Acute Lesion Topography in Initial Ischemic Stroke Severity and Long-Term Functional Outcomes , 2015, Stroke.

[28]  A. Demchuk,et al.  Thrombectomy within 8 hours after symptom onset in ischemic stroke. , 2015, The New England journal of medicine.

[29]  H. Diener,et al.  Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. , 2015, The New England journal of medicine.

[30]  M. Krause,et al.  Endovascular therapy for ischemic stroke with perfusion-imaging selection. , 2015, The New England journal of medicine.

[31]  Eric E. Smith,et al.  Randomized assessment of rapid endovascular treatment of ischemic stroke. , 2015, The New England journal of medicine.

[32]  Hester F. Lingsma,et al.  A randomized trial of intraarterial treatment for acute ischemic stroke. , 2015, The New England journal of medicine.

[33]  Steven C Cramer,et al.  Stem cells as an emerging paradigm in stroke 3: enhancing the development of clinical trials. , 2014, Stroke.

[34]  C. Lang,et al.  Assessment of upper extremity impairment, function, and activity after stroke: foundations for clinical decision making. , 2013, Journal of hand therapy : official journal of the American Society of Hand Therapists.

[35]  Pamela W Duncan,et al.  Promoting neuroplasticity and recovery after stroke: future directions for rehabilitation clinical trials. , 2013, Current opinion in neurology.

[36]  A. Hillis,et al.  Reperfusion of specific cortical areas is associated with improvement in distinct forms of hemispatial neglect , 2012, Cortex.

[37]  S. Warach,et al.  Standardizing the Structure of Stroke Clinical and Epidemiologic Research Data: The National Institute of Neurological Disorders and Stroke (NINDS) Stroke Common Data Element (CDE) Project , 2012, Stroke.

[38]  Jeffrey L Saver,et al.  Optimal End Points for Acute Stroke Therapy Trials: Best Ways to Measure Treatment Effects of Drugs and Devices , 2011, Stroke.

[39]  Gordon N Dutton,et al.  Visual neglect following stroke: current concepts and future focus. , 2011, Survey of ophthalmology.

[40]  L. Krupp,et al.  A phase 3 trial of extended release oral dalfampridine in multiple sclerosis , 2010, Annals of neurology.

[41]  Karla J. Ryckborst,et al.  The Beta-hCG+Erythropoietin in Acute Stroke (BETAS) Study: A 3-Center, Single-Dose, Open-Label, Noncontrolled, Phase IIa Safety Trial , 2010, Stroke.

[42]  K. Traynor.  Dalfampridine approved for MS. , 2010, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[43]  M. L. Lauzon,et al.  Atlas-Based Topographical Scoring for Magnetic Resonance Imaging of Acute Stroke , 2010, Stroke.

[44]  P. Schellinger,et al.  Strengthening the link: the critical role of children in the stroke chain of recovery. , 2008, Stroke.

[45]  Lauren L. Cloutman,et al.  Site of the ischemic penumbra as a predictor of potential for recovery of functions , 2008, Neurology.

[46]  E. Lo,et al.  A new penumbra: transitioning from injury into repair after stroke , 2008, Nature Medicine.

[47]  S. Cramer,et al.  The case for modality-specific outcome measures in clinical trials of stroke recovery-promoting agents. , 2007, Stroke.

[48]  Peter B Barker,et al.  Restoring Cerebral Blood Flow Reveals Neural Regions Critical for Naming , 2006, The Journal of Neuroscience.

[49]  G. Donnan,et al.  1,026 Experimental treatments in acute stroke , 2006, Annals of neurology.

[50]  Christopher J Weir,et al.  Comparison of stratification and adaptive methods for treatment allocation in an acute stroke clinical trial. , 2004, Statistics in medicine.

[51]  R. Katz.  FDA: Evidentiary standards for drug development and approval , 2004, NeuroRX.

[52]  Argye E. Hillis,et al.  Variability in subcortical aphasia is due to variable sites of cortical hypoperfusion , 2004, Brain and Language.

[53]  Steven C Cramer,et al.  Improved understanding of cortical injury by incorporating measures of functional anatomy. , 2003, Brain : a journal of neurology.

[54]  R. Zorowitz,et al.  Medical complications after stroke. , 1999, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.

[55]  W. Koroshetz,et al.  Infarct volume as a surrogate or auxiliary outcome measure in ischemic stroke clinical trials. The RANTTAS Investigators. , 1999, Stroke.

[56]  T. Walley,et al.  Outcomes , 1995, Too Many Lawyers?.

[57]  R D Luce,et al.  Measurement Scales on the Continuum , 1987, Science.

[58]  S S Stevens,et al.  On the Theory of Scales of Measurement. , 1946, Science.

[59]  S. Jasko,et al.  Therapy , 1881, The American journal of dental science.

[60]  Akshay S. Desai,et al.  2017 Cardiovascular and Stroke Endpoint Definitions for Clinical Trials. , 2018, Journal of the American College of Cardiology.

[61]  A. Jones,et al.  211 Anterior cruciate ligament injury severity and long-term functional outcomes , 2018 .

[62]  J. Broderick,et al.  Evolution of the Modified Rankin Scale and Its Use in Future Stroke Trials. , 2017, Stroke.

[63]  C. Colby.  Neural Basis of Cognition , 2016 .

[64]  F. Sallustio,et al.  Thrombectomy within 8 hours after symptom onset in ischemic stroke , 2015 .

[65]  J. Olver,et al.  Navigating the poststroke continuum of care. , 2013, Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association.

[66]  A. Minagar.  A Phase 3 Trial of Extended Release Oral Dalfampridine in Multiple Sclerosis , 2011 .

[67]  Myrna F. Schwartz,et al.  The Philadelphia Naming Test: Scoring and Rationale , 1996 .