Continuous separation of lipid particles from erythrocytes by means of laminar flow and acoustic standing wave forces.

Improved continuous acoustic particle separation (separation efficiency close to 100%) and separation of erythrocytes (red blood cells) from lipid microemboli in whole blood is reported.

[1]  W D White,et al.  Defining neuropsychological dysfunction after coronary artery bypass grafting. , 1996, The Annals of thoracic surgery.

[2]  K. Yosioka,et al.  Acoustic radiation pressure on a compressible sphere , 1955 .

[3]  Louis Vessot King,et al.  On the Acoustic Radiation Pressure on Spheres , 1934 .

[4]  Donald L. Feke,et al.  Methodology for fractionating suspended particles using ultrasonic standing wave and divided flow fields , 1995 .

[5]  Shin-ichiro Umemura,et al.  Concentration and Fractionation of Small Particles in Liquid by Ultrasound , 1995 .

[6]  C. Holm,et al.  Hormone-sensitive lipase and neutral cholesteryl ester lipase. , 1999, Methods in molecular biology.

[7]  M. A. Bell,et al.  Brain microemboli during cardiac surgery or aortography , 1990, Annals of neurology.

[8]  Jeremy J. Hawkes,et al.  Force field particle filter, combining ultrasound standing waves and laminar flow , 2001 .

[9]  F W Kremkau,et al.  Physical principles of ultrasound. , 1975, Seminars in roentgenology.

[10]  C. Maggi,et al.  A distribution study with (14)C-otilonium bromide in the rat: evidence for selective tropism for large intestine after oral administration. , 2000, Drug metabolism and disposition: the biological fate of chemicals.

[11]  Neil M. White,et al.  A silicon microfluidic ultrasonic separator , 2003 .

[12]  Thomas Laurell,et al.  Acoustic control of suspended particles in micro fluidic chips. , 2004, Lab on a chip.

[13]  D. Spain,et al.  Does Cell-Saver Blood Administration and Free Hemoglobin Load Cause Renal Dysfunction? , 2001, The American surgeon.

[14]  L. Gor’kov,et al.  On the forces acting on a small particle in an acoustical field in an ideal fluid , 1962 .