A Novel Electrochemical Microfluidic Chip Combined with Multiple Biomarkers for Early Diagnosis of Gastric Cancer

[1]  Yan Deng,et al.  Genetic Variation of BCL2 (rs2279115), NEIL2 (rs804270), LTA (rs909253), PSCA (rs2294008) and PLCE1 (rs3765524, rs10509670) Genes and Their Correlation to Gastric Cancer Risk Based on Universal Tagged Arrays and Fe3O4 Magnetic Nanoparticles. , 2015, Journal of biomedical nanotechnology.

[2]  Chao Li,et al.  CD44v6 Monoclonal Antibody-Conjugated Gold Nanostars for Targeted Photoacoustic Imaging and Plasmonic Photothermal Therapy of Gastric Cancer Stem-like Cells , 2015, Theranostics.

[3]  Xiao Zhi,et al.  Circulating MiR-16-5p and MiR-19b-3p as Two Novel Potential Biomarkers to Indicate Progression of Gastric Cancer , 2015, Theranostics.

[4]  Fátima Carneiro,et al.  Unmet needs and challenges in gastric cancer: the way forward. , 2014, Cancer treatment reviews.

[5]  Y. Niv,et al.  Gastric mucin expression in first-degree relatives of gastric cancer patients , 2014, European journal of gastroenterology & hepatology.

[6]  Jun Zhang,et al.  Assessment of the Potential Diagnostic Value of Serum p53 Antibody for Cancer: A Meta-Analysis , 2014, PloS one.

[7]  C. Li,et al.  HAI-178 antibody-conjugated fluorescent magnetic nanoparticles for targeted imaging and simultaneous therapy of gastric cancer , 2014, Nanoscale Research Letters.

[8]  Xiao Zhi,et al.  A novel HBV genotypes detecting system combined with microfluidic chip, loop-mediated isothermal amplification and GMR sensors. , 2014, Biosensors & bioelectronics.

[9]  Saeid Nahavandi,et al.  Microfluidic platforms for biomarker analysis. , 2014, Lab on a chip.

[10]  Zhanfang Ma,et al.  A label-free immunosensor based on graphene nanocomposites for simultaneous multiplexed electrochemical determination of tumor markers. , 2014, Biosensors & bioelectronics.

[11]  M. Canbaz,et al.  Electrochemical biosensor based on self-assembled monolayers modified with gold nanoparticles for detection of HER-3. , 2014, Analytica chimica acta.

[12]  Chao Li,et al.  A CCD-based reader combined with CdS quantum dot-labeled lateral flow strips for ultrasensitive quantitative detection of CagA , 2014, Nanoscale Research Letters.

[13]  Xiao Zhi,et al.  Identification of Volatile Biomarkers of Gastric Cancer Cells and Ultrasensitive Electrochemical Detection based on Sensing Interface of Au-Ag Alloy coated MWCNTs , 2014, Theranostics.

[14]  Gui-ying Zhang,et al.  The value of serum pepsinogen levels for the diagnosis of gastric diseases in Chinese Han people in midsouth China , 2014, BMC Gastroenterology.

[15]  Cheng-Fu Yang,et al.  Prepare dispersed CIS nano-scale particles and spray coating CIS absorber layers using nano-scale precursors , 2014, Nanoscale Research Letters.

[16]  Zhanfang Ma,et al.  Electrochemical immunosensor for simultaneous detection of multiplex cancer biomarkers based on graphene nanocomposites. , 2013, Biosensors & bioelectronics.

[17]  Reinhard Niessner,et al.  Multiplexed electrochemical immunoassay of biomarkers using metal sulfide quantum dot nanolabels and trifunctionalized magnetic beads. , 2013, Biosensors & bioelectronics.

[18]  F. Başak,et al.  CEA and CA 19-9 are still valuable markers for the prognosis of colorectal and gastric cancer patients. , 2013, Asian Pacific journal of cancer prevention : APJCP.

[19]  Zhe Wang,et al.  Photosensitizer-conjugated silica-coated gold nanoclusters for fluorescence imaging-guided photodynamic therapy. , 2013, Biomaterials.

[20]  Jun Yu,et al.  Epigenetic-mediated tumor suppressor genes as diagnostic or prognostic biomarkers in gastric cancer , 2013, Expert review of molecular diagnostics.

[21]  Fei Kong,et al.  Serum pepsinogen II is a better diagnostic marker in gastric cancer. , 2012, World journal of gastroenterology.

[22]  Daxiang Cui,et al.  Folic acid-conjugated LaF3:Yb,Tm@SiO2 nanoprobes for targeting dual-modality imaging of upconversion luminescence and X-ray computed tomography. , 2012, The journal of physical chemistry. B.

[23]  P. Malfertheiner,et al.  Helicobacter pylori: clinical management , 2012, Current opinion in gastroenterology.

[24]  Daxiang Cui,et al.  HER2 monoclonal antibody conjugated RNase-A-associated CdTe quantum dots for targeted imaging and therapy of gastric cancer. , 2012, Biomaterials.

[25]  Guangxia Shen,et al.  Light‐Triggered Theranostics Based on Photosensitizer‐Conjugated Carbon Dots for Simultaneous Enhanced‐Fluorescence Imaging and Photodynamic Therapy , 2012, Advanced materials.

[26]  H. Chung,et al.  Prognostic value of postoperative CA19-9 normalization in patients with advanced gastric cancer. , 2012, Hepato-gastroenterology.

[27]  D. Cui,et al.  Cell-penetrating magnetic nanoparticles for highly efficient delivery and intracellular imaging of siRNA. , 2012, Biomacromolecules.

[28]  Xin-en Huang,et al.  Comparison of serum tumor associated material (TAM) with conventional biomarkers in cancer patients. , 2012, Asian Pacific journal of cancer prevention : APJCP.

[29]  Chuanqing Zhou,et al.  RGD-conjugated gold nanorods induce radiosensitization in melanoma cancer cells by downregulating αvβ3 expression , 2012, International journal of nanomedicine.

[30]  Xiao Zhi,et al.  Quick genotyping detection of HBV by giant magnetoresistive biochip combined with PCR and line probe assay. , 2012, Lab on a chip.

[31]  T. Hibi,et al.  Fasting Gastric pH of Japanese Subjects Stratified by IgG Concentration Against Helicobacter pylori and Pepsinogen Status , 2011, Helicobacter.

[32]  Hengyi Xu,et al.  Antibody conjugated magnetic iron oxide nanoparticles for cancer cell separation in fresh whole blood. , 2011, Biomaterials.

[33]  Ding Li,et al.  A prototype of giant magnetoimpedance-based biosensing system for targeted detection of gastric cancer cells. , 2011, Biosensors & bioelectronics.

[34]  Ruo Yuan,et al.  A novel electrochemical immunoassay based on diazotization-coupled functionalized bioconjugates as trace labels for ultrasensitive detection of carcinoembryonic antigen. , 2011, Biosensors & bioelectronics.

[35]  C. Mathers,et al.  Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008 , 2010, International journal of cancer.

[36]  Sajjad Karim,et al.  Correlation of p53 over-expression and alteration in p53 gene detected by polymerase chain reaction-single strand conformation polymorphism in adenocarcinoma of gastric cancer patients from India. , 2009, World journal of gastroenterology.

[37]  Se Young Oh,et al.  Electrochemical detection of cardiac troponin I using a microchip with the surface-functionalized poly(dimethylsiloxane) channel. , 2007, Biosensors & bioelectronics.

[38]  H. B. Halsall,et al.  Microfluidic immunosensor systems. , 2005, Biosensors & bioelectronics.

[39]  Huajian Gao,et al.  A microarray-based gastric carcinoma prewarning system. , 2005, World journal of gastroenterology.

[40]  N. Duraker,et al.  The prognostic significance of gastric juice CA 19-9 and CEA levels in gastric carcinoma patients. , 2002, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.

[41]  M. Morris,et al.  A peptide carrier for the delivery of biologically active proteins into mammalian cells , 2001, Nature Biotechnology.

[42]  M A Fujino,et al.  Accuracy of screening for gastric cancer using serum pepsinogen concentrations , 1999, Gut.

[43]  K. Haruma,et al.  Correlation of ratio of serum pepsinogen I and II with prevalence of gastric cancer and adenoma in Japanese subjects , 1998, American Journal of Gastroenterology.

[44]  M. Imamura,et al.  Clinical significance of serum p53 antigen in patients with pancreatic carcinomas. , 1997, Gut.

[45]  S. Hirohashi,et al.  p53 Mutation in gastric cancer: A genetic model for carcinogenesis is common to gastric and colorectal cancer , 1993, International journal of cancer.

[46]  J. Chang-Claude,et al.  Polymorphisms of Helicobacter pylori signaling pathway genes and gastric cancer risk in the European prospective investigation into cancer‐eurgast cohort , 2014, International journal of cancer.

[47]  H. Shimada,et al.  Clinical significance of serum tumor markers for gastric cancer: a systematic review of literature by the Task Force of the Japanese Gastric Cancer Association , 2013, Gastric Cancer.

[48]  M. Sharafkhah,et al.  Serum gastrin and the pepsinogen I/II ratio as markers for diagnosis of premalignant gastric lesions. , 2013, Asian Pacific journal of cancer prevention : APJCP.

[49]  Alberto Escarpa,et al.  Electrochemical immunosensing on board microfluidic chip platforms , 2012 .

[50]  Kan Wang,et al.  BRCAA 1 monoclonal antibody conjugated fluorescent magnetic nanoparticles for in vivo targeted magnetofluorescent imaging of gastric cancer , 2011 .

[51]  B. Xiong,et al.  Investigation of serum tumor markers in the diagnosis of gastric cancer. , 2011, Hepato-gastroenterology.

[52]  Qing Chen,et al.  Serum p53 protein and anti-p53 antibodies are associated with increased cancer risk: a case–control study of 569 patients and 879 healthy controls , 2009, Molecular Biology Reports.

[53]  Abbreviations: BSA- Bovine Serum Albumin , 2022 .