Three-dimensional black-blood MR imaging of carotid arteries with segmented steady-state free precession: initial experience.

This HIPAA-compliant study had institutional review board approval. Informed consent was obtained. The purpose was to prospectively evaluate a segmented three-dimensional (3D) double inversion recovery (DIR)-prepared steady-state free precession (SSFP) magnetic resonance (MR) imaging sequence for fast high-spatial-resolution black-blood carotid arterial wall imaging. Carotid wall-lumen contrast-to-noise ratio (CNR) obtained with this sequence was compared with those obtained with two-dimensional (2D) single- and multisection black-blood fast spin-echo (SE) sequences. MR imaging of both carotid artery bifurcations over 3 cm of transverse coverage was performed in eight volunteers (seven men, one woman; age range, 26-56 years) with no known history of carotid artery disease. Adjusted for section thickness and imaging time per section, higher effective mean CNR was achieved with segmented 3D DIR-prepared SSFP than with single-section 2D DIR-prepared fast SE or multisection 2D saturation-band fast SE (P < .05). Segmented 3D DIR-prepared SSFP enables black-blood carotid arterial wall MR imaging with contiguous thin-section coverage and greater imaging speed and effective CNR than conventional 2D fast SE techniques.

[1]  D. Holdsworth,et al.  Characterization of common carotid artery blood-flow waveforms in normal human subjects , 1999, Physiological measurement.

[2]  M. Bronskill,et al.  T1, T2 relaxation and magnetization transfer in tissue at 3T , 2005, Magnetic resonance in medicine.

[3]  D Chien,et al.  Fast selective black blood MR imaging. , 1991, Radiology.

[4]  C Yuan,et al.  Characterization of atherosclerotic plaques at the carotid bifurcation: correlation of high-resolution MR imaging with histologic analysis--preliminary study. , 1997, Radiographics : a review publication of the Radiological Society of North America, Inc.

[5]  Gerhard Laub,et al.  TrueFISP--technical considerations and cardiovascular applications. , 2003, European journal of radiology.

[6]  Bob S. Hu,et al.  High‐resolution three‐dimensional in vivo imaging of atherosclerotic plaque , 1999, Magnetic resonance in medicine.

[7]  Chun Yuan,et al.  In vivo accuracy of multisequence MR imaging for identifying unstable fibrous caps in advanced human carotid plaques , 2003, Journal of magnetic resonance imaging : JMRI.

[8]  Jürgen Hennig,et al.  Comparison of different flip angle variation functions for improved signal behavior in SSFP sequences , 2004 .

[9]  Chun Yuan,et al.  Classification of Human Carotid Atherosclerotic Lesions With In Vivo Multicontrast Magnetic Resonance Imaging , 2002, Circulation.

[10]  Richard Lorne Ehman,et al.  Spatial presaturation: a method for suppressing flow artifacts and improving depiction of vascular anatomy in MR imaging. , 1987 .

[11]  J C Gore,et al.  The Loss of Small Objects in Variable TE Imaging: Implications for FSE, RARE, and EPI , 1992, Magnetic resonance in medicine.

[12]  Hee Kwon Song,et al.  Multislice double inversion pulse sequence for efficient black‐blood MRI , 2002, Magnetic resonance in medicine.

[13]  Dennis L Parker,et al.  Improved efficiency in double‐inversion fast spin‐echo imaging , 2002, Magnetic resonance in medicine.

[14]  V. Fuster,et al.  Magnetic resonance images lipid, fibrous, calcified, hemorrhagic, and thrombotic components of human atherosclerosis in vivo. , 1996, Circulation.

[15]  J Listerud,et al.  First principles of fast spin echo. , 1992, Magnetic resonance quarterly.

[16]  Z. Fayad,et al.  Comparison of gated and nongated fast multislice black‐blood carotid imaging using rapid extended coverage and inflow/outflow saturation techniques , 2005, Journal of magnetic resonance imaging : JMRI.

[17]  C. Hardy,et al.  A review of 1H nuclear magnetic resonance relaxation in pathology: are T1 and T2 diagnostic? , 1987, Medical physics.

[18]  D A Steinman,et al.  On the nature and reduction of plaque‐mimicking flow artifacts in black blood MRI of the carotid bifurcation , 1998, Magnetic resonance in medicine.

[19]  Jennifer Keegan,et al.  Volume‐selective 3D turbo spin echo imaging for vascular wall imaging and distensibility measurement , 2003, Journal of magnetic resonance imaging : JMRI.

[20]  W J Rogers,et al.  Characterization of signal properties in atherosclerotic plaque components by intravascular MRI. , 2000, Arteriosclerosis, thrombosis, and vascular biology.

[21]  Chun Yuan,et al.  In vivo accuracy of multispectral magnetic resonance imaging for identifying lipid-rich necrotic cores and intraplaque hemorrhage in advanced human carotid plaques. , 2002 .

[22]  William Insull,et al.  Bilateral Symmetry of Human Carotid Artery Atherosclerosis , 2002, Stroke.

[23]  S. Glagov,et al.  Juxtalumenal location of plaque necrosis and neoformation in symptomatic carotid stenosis. , 1997, Journal of vascular surgery.

[24]  C Yuan,et al.  Phased‐Array Magnetic Resonance Imaging of the Carotid Artery Bifurcation: Preliminary Results in Healthy Volunteers and a Patient with Aherosclerotic Disease , 1995, Journal of magnetic resonance imaging : JMRI.

[25]  C Yuan,et al.  Comparison of carotid vessel wall area measurements using three different contrast-weighted black blood MR imaging techniques. , 2001, Magnetic resonance imaging.

[26]  Zahi A Fayad,et al.  Rapid extended coverage simultaneous multisection black-blood vessel wall MR imaging. , 2004, Radiology.

[27]  J. Pauly,et al.  Characterization and reduction of the transient response in steady‐state MR imaging , 2001, Magnetic resonance in medicine.