Experimental Methods in Testing of Tissues and Implants*

Three experimental tasks are of primary interest in biomechanics: determination of the mechanical properties of biomaterials, including tissues and artificial materials; validation of the mechanical reliability of implantable devices; assessment of the compatibility of the mechanical properties of such devices with the surrounding biological environment. Due to the complexity of the in vivo conditions, most of these studies are performed on in vitro models. This contribution presents a review of some methods that are currently utilised at the Laboratory of Biological Structure Mechanics at the Politecnico of Milan.

[1]  D L Butler,et al.  Comparison of material properties in fascicle-bone units from human patellar tendon and knee ligaments. , 1986, Journal of biomechanics.

[2]  Michael S. Sacks,et al.  Orthotropic Mechanical Properties of Chemically Treated Bovine Pericardium , 1998, Annals of Biomedical Engineering.

[3]  T D Brown,et al.  Techniques for mechanical stimulation of cells in vitro: a review. , 2000, Journal of biomechanics.

[4]  C. Frank,et al.  Water content alters viscoelastic behaviour of the normal adolescent rabbit medial collateral ligament. , 1992, Journal of biomechanics.

[5]  R. Haut,et al.  The effects of test environment and cyclic stretching on the failure properties of human patellar tendons , 1990, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[6]  L Cristofolini,et al.  A critical analysis of stress shielding evaluation of hip prostheses. , 1997, Critical reviews in biomedical engineering.

[7]  An in vitro methodology for evaluating the mechanical properties of aortic vascular prostheses. , 2002, Artificial organs.

[8]  J. Barbenel,et al.  Mechanics of native bovine pericardium. II. A structure based model for the anisotropic mechanical behaviour of the tissue. , 1994, Biomaterials.

[9]  Y. Fung,et al.  Biomechanics: Mechanical Properties of Living Tissues , 1981 .

[10]  M. Sato [Mechanical properties of living tissues]. , 1986, Iyo denshi to seitai kogaku. Japanese journal of medical electronics and biological engineering.

[11]  E. Schneider,et al.  Long-term in vivo alterations of polyester vascular grafts in humans. , 1997, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

[12]  V. Quaglini,et al.  A single integral finite strain characterization of soft connective tissues and parameter identification , 2000 .

[13]  R Pietrabissa,et al.  An in vitro study on compensation of mismatch of screw versus cement-retained implant supported fixed prostheses. , 2000, Clinical oral implants research.

[14]  Roberto Contro,et al.  Lumbar dura mater biomechanics: experimental characterization and scanning electron microscopy observations. , 1999, Anesthesia and analgesia.

[15]  Tomaso Villa,et al.  THE BIOMECHANICS OF INTRAMEDULLARY NAILING: A PROTOCOL FOR LABORATORY TESTING , 2002 .

[16]  S. Woo,et al.  Effects of postmortem storage by freezing on ligament tensile behavior. , 1986, Journal of biomechanics.