L-arginine metabolism in myeloid cells controls T-lymphocyte functions.

[1]  U. Grohmann,et al.  Tolerance, DCs and tryptophan: much ado about IDO. , 2003, Trends in immunology.

[2]  M. Colombo,et al.  IL-4-Induced Arginase 1 Suppresses Alloreactive T Cells in Tumor-Bearing Mice1 , 2003, The Journal of Immunology.

[3]  A. Gobert,et al.  Arginases in parasitic diseases. , 2003, Trends in parasitology.

[4]  S. Gordon Alternative activation of macrophages , 2003, Nature Reviews Immunology.

[5]  James Leiper,et al.  Blocking NO synthesis: how, where and why? , 2002, Nature Reviews Drug Discovery.

[6]  P. Allavena,et al.  Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. , 2002, Trends in immunology.

[7]  U. Grohmann,et al.  CTLA-4–Ig regulates tryptophan catabolism in vivo , 2002, Nature Immunology.

[8]  M. Fresno,et al.  Immunosuppression during acute Trypanosoma cruzi infection: involvement of Ly6G (Gr1(+))CD11b(+ )immature myeloid suppressor cells. , 2002, International immunology.

[9]  J. Ochoa,et al.  Regulation of T Cell Receptor CD3ζ Chain Expression byl-Arginine* , 2002, The Journal of Biological Chemistry.

[10]  D. Gabrilovich,et al.  Immature myeloid cells and cancer-associated immune suppression , 2002, Cancer Immunology, Immunotherapy.

[11]  A. Visintin,et al.  Myeloid Suppressor Lines Inhibit T Cell Responses by an NO-Dependent Mechanism1 , 2002, The Journal of Immunology.

[12]  Michel C. Nussenzweig,et al.  Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[13]  D. Keskin,et al.  Functional expression of indoleamine 2,3-dioxygenase by murine CD8α+ dendritic cells , 2002 .

[14]  A. Frey,et al.  Tumor-Infiltrating Macrophages Induce Apoptosis in Activated CD8+ T Cells by a Mechanism Requiring Cell Contact and Mediated by Both the Cell-Associated Form of TNF and Nitric Oxide1 , 2001, The Journal of Immunology.

[15]  A. Frey,et al.  CD8+ Tumor-Infiltrating T Cells Are Deficient in Perforin-Mediated Cytolytic Activity Due to Defective Microtubule-Organizing Center Mobilization and Lytic Granule Exocytosis , 2001, The Journal of Immunology.

[16]  V. Bronte,et al.  Tumor-induced immune dysfunctions caused by myeloid suppressor cells. , 2001, Journal of immunotherapy.

[17]  M. Miyagi,et al.  Proteomic method identifies proteins nitrated in vivo during inflammatory challenge , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[18]  Christian Bogdan,et al.  Nitric oxide and the immune response , 2001, Nature Immunology.

[19]  K. Racké,et al.  Concomitant down-regulation of L-arginine transport and nitric oxide (NO) synthesis in rat alveolar macrophages by the polyamine spermine. , 2001, Pulmonary pharmacology & therapeutics.

[20]  D. Ash,et al.  Classical and slow-binding inhibitors of human type II arginase. , 2001, Biochemistry.

[21]  P. Kearney,et al.  Effects of L-arginine on the proliferation of T lymphocyte subpopulations. , 2001, JPEN. Journal of parenteral and enteral nutrition.

[22]  H. Young,et al.  Immortalized Myeloid Suppressor Cells Trigger Apoptosis in Antigen-Activated T Lymphocytes1 , 2000, The Journal of Immunology.

[23]  R. Ronca,et al.  Identification of a CD11b(+)/Gr-1(+)/CD31(+) myeloid progenitor capable of activating or suppressing CD8(+) T cells. , 2000, Blood.

[24]  Shu-Hsia Chen,et al.  Gr-1+ Myeloid Cells Derived from Tumor-Bearing Mice Inhibit Primary T Cell Activation Induced Through CD3/CD28 Costimulation1 , 2000, The Journal of Immunology.

[25]  Kristi Kincaid,et al.  M-1/M-2 Macrophages and the Th1/Th2 Paradigm1 , 2000, The Journal of Immunology.

[26]  M. Howard,et al.  Early myeloid cells are high producers of nitric oxide upon CD40 plus IFN‐γ stimulation through a mechanism dependent on endogenous TNF‐α and IL‐1α , 2000 .

[27]  D. Munn,et al.  Tryptophan catabolism and T-cell tolerance: immunosuppression by starvation? , 1999, Immunology today.

[28]  R. Kiessling,et al.  Tumor-induced immune dysfunction , 1999, Cancer Immunology, Immunotherapy.

[29]  T. Gotoh,et al.  Regulation of the genes for arginase isoforms and related enzymes in mouse macrophages by lipopolysaccharide. , 1999, American journal of physiology. Endocrinology and metabolism.

[30]  P. Hwu,et al.  Unopposed production of granulocyte-macrophage colony-stimulating factor by tumors inhibits CD8+ T cell responses by dysregulating antigen-presenting cell maturation. , 1999, Journal of immunology.

[31]  R. Radi,et al.  Peroxynitrite inhibits T lymphocyte activation and proliferation by promoting impairment of tyrosine phosphorylation and peroxynitrite-driven apoptotic death. , 1999, Journal of immunology.

[32]  J. Albina,et al.  Regulation of arginase isoforms I and II by IL-4 in cultured murine peritoneal macrophages. , 1999, The American journal of physiology.

[33]  S. Rosenberg,et al.  Apoptotic death of CD8+ T lymphocytes after immunization: induction of a suppressive population of Mac-1+/Gr-1+ cells. , 1998, Journal of immunology.

[34]  Guoyao Wu,et al.  Arginine metabolism: nitric oxide and beyond. , 1998, The Biochemical journal.

[35]  G. Trinchieri,et al.  Immune Suppression by Recombinant Interleukin (rIL)-12 Involves Interferon γ Induction of Nitric Oxide Synthase 2 (iNOS) Activity: Inhibitors of NO Generation Reveal the Extent of rIL-12 Vaccine Adjuvant Effect , 1998, The Journal of experimental medicine.

[36]  S. Morris,et al.  Differential regulation of arginases and inducible nitric oxide synthase in murine macrophage cells. , 1998, American journal of physiology. Endocrinology and metabolism.

[37]  J. Zweier,et al.  Inducible Nitric-oxide Synthase Generates Superoxide from the Reductase Domain* , 1998, The Journal of Biological Chemistry.

[38]  P. Holt,et al.  Macrophage-derived nitric oxide regulates T cell activation via reversible disruption of the Jak3/STAT5 signaling pathway. , 1998, Journal of immunology.

[39]  M. Munder,et al.  Alternative metabolic states in murine macrophages reflected by the nitric oxide synthase/arginase balance: competitive regulation by CD4+ T cells correlates with Th1/Th2 phenotype. , 1998, Journal of immunology.

[40]  W. Farrar,et al.  Nitric oxide and thiol redox regulation of Janus kinase activity. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[41]  J. Zweier,et al.  Superoxide and peroxynitrite generation from inducible nitric oxide synthase in macrophages. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[42]  M. Takiguchi,et al.  Coinduction of Nitric-oxide Synthase and Arginase I in Cultured Rat Peritoneal Macrophages and Rat Tissues in Vivo by Lipopolysaccharide* , 1997, The Journal of Biological Chemistry.

[43]  M. Caldwell,et al.  Differential regulation of macrophage arginine metabolism: a proposed role in wound healing. , 1997, The American journal of physiology.

[44]  M. Goligorsky,et al.  Decreased L-arginine during peritonitis in ESRD patients on peritoneal dialysis. , 1997, Advances in peritoneal dialysis. Conference on Peritoneal Dialysis.

[45]  J. Kung,et al.  Suppression of in vitro cytotoxic response by macrophages due to induced arginase , 1977, The Journal of experimental medicine.