Energy Dissipation in Ex Vivo Porcine Liver During Electrosurgery

This paper explores energy dissipation in ex vivo liver tissue during radiofrequency current excitation with application in electrosurgery. Tissue surface temperature for monopolar electrode configuration is measured using infrared thermometry. The experimental results are fitted to a finite-element model for transient heat transfer taking into account energy storage and conduction in order to extract information about “apparent” specific heat, which encompasses storage and phase change. The average apparent specific heat determined for low temperatures is in agreement with published data. However, at temperatures approaching the boiling point of water, apparent specific heat increases by a factor of five, indicating that vaporization plays an important role in the energy dissipation through latent heat loss.

[1]  Suvranu De,et al.  Common uses and cited complications of energy in surgery , 2013, Surgical Endoscopy.

[2]  T E Cooper,et al.  Correlation of thermal properties of some human tissue with water content. , 1971, Aerospace medicine.

[3]  I. Chang,et al.  Considerations for Thermal Injury Analysis for RF Ablation Devices , 2010, The open biomedical engineering journal.

[4]  O. Minet,et al.  Determination of the specific heat capacity of healthy and tumorous human tissue , 1995 .

[5]  Albert J. Shih,et al.  Electrosurgical Vessel Sealing Tissue Temperature: Experimental Measurement and Finite Element Modeling , 2013, IEEE Transactions on Biomedical Engineering.

[6]  John C. Bischof,et al.  Thermal Processing of Biological Tissue at High Temperatures: Impact of Protein Denaturation and Water Loss on the Thermal Properties of Human and Porcine Liver in the Range 25–80 °C , 2013 .

[7]  H. F. Bowman,et al.  The simultaneous measurement of thermal conductivity, thermal diffusivity, and perfusion in small volumes of tissue. , 1984, Journal of biomechanical engineering.

[8]  John G. Webster,et al.  Measurement and Analysis of Tissue Temperature During Microwave Liver Ablation , 2007, IEEE Transactions on Biomedical Engineering.

[9]  Thomas Stein,et al.  Determination of the temperature-dependent electric conductivity of liver tissue ex vivo and in vivo: Importance for therapy planning for the radiofrequency ablation of liver tumours , 2010, International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group.

[10]  P. Nordal,et al.  New developments in photothermal radiometry , 1985 .

[11]  J. Leonetti,et al.  Thermoprotective Mechanisms of Irrigation During Bipolar Cautery , 1997, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[12]  F. Duck.  Physical properties of tissue , 1990 .

[13]  Cooper Te,et al.  Correlation of thermal properties of some human tissue with water content. , 1971 .

[14]  Nader N Massarweh,et al.  Electrosurgery: history, principles, and current and future uses. , 2006, Journal of the American College of Surgeons.

[15]  E. Arens,et al.  Convective and radiative heat transfer coefficients for individual human body segments , 1997, International journal of biometeorology.

[16]  Isaac Chang,et al.  Finite Element Analysis of Hepatic Radiofrequency Ablation Probes using Temperature-Dependent Electrical Conductivity , 2003, Biomedical engineering online.

[17]  Albert J. Shih,et al.  Monopolar Electrosurgical Thermal Management for Minimizing Tissue Damage , 2012, IEEE Transactions on Biomedical Engineering.

[18]  G Benzing,et al.  Measurement of the ohmic electrode-tissue contact resistance and the voltage applied to myocardium. , 1980, Journal of biomedical engineering.

[19]  Enrique J Berjano,et al.  Theoretical modeling for radiofrequency ablation: state-of-the-art and challenges for the future , 2006, Biomedical engineering online.

[20]  Dieter Haemmerich,et al.  In vitro measurements of temperature-dependent specific heat of liver tissue. , 2006, Medical engineering & physics.

[21]  John G. Webster,et al.  Expanding the Bioheat Equation to Include Tissue Internal Water Evaporation During Heating , 2007, IEEE Transactions on Biomedical Engineering.

[22]  John E. Bertie,et al.  Infrared Intensities of Liquids XX: The Intensity of the OH Stretching Band of Liquid Water Revisited, and the Best Current Values of the Optical Constants of H2O(l) at 25°C between 15,000 and 1 cm−1 , 1996 .

[23]  R L Mahajan,et al.  Temperature dependence of thermal conductivity of biological tissues , 2003, Physiological measurement.