Molecular Basis for Differential Anion Binding and Proton Coupling in the Cl(-)/H(+) Exchanger ClC-ec1.
暂无分享,去创建一个
Emad Tajkhorshid | Wei Han | Merritt Maduke | E. Tajkhorshid | W. Han | M. Maduke | Tao Jiang | T. Jiang | Wei Han
[1] Ludmila Kolmakova-Partensky,et al. Design, function, and structure of a monomeric CLC transporter , 2010, Nature.
[2] G. Voth,et al. Storage of an excess proton in the hydrogen-bonded network of the d-pathway of cytochrome C oxidase: identification of a protonated water cluster. , 2007, Journal of the American Chemical Society.
[3] Carole Williams,et al. Separate Ion Pathways in a Cl−/H+ Exchanger , 2005, The Journal of general physiology.
[4] Christopher Miller,et al. Secondary active transport mediated by a prokaryotic homologue of ClC Cl- channels , 2004, Nature.
[5] H. Jayaram,et al. Structure of a slow CLC Cl⁻/H+ antiporter from a cyanobacterium. , 2011, Biochemistry.
[6] T. Jentsch,et al. Voltage-dependent electrogenic chloride/proton exchange by endosomal CLC proteins , 2005, Nature.
[7] Hoover,et al. Canonical dynamics: Equilibrium phase-space distributions. , 1985, Physical review. A, General physics.
[8] David L Bostick,et al. Exterior site occupancy infers chloride-induced proton gating in a prokaryotic homolog of the ClC chloride channel. , 2004, Biophysical journal.
[9] Youn Jo Ko,et al. Chloride ion conduction without water coordination in the pore of ClC protein , 2009, J. Comput. Chem..
[10] B. Wallace,et al. The pore dimensions of gramicidin A. , 1993, Biophysical journal.
[11] Laxmikant V. Kalé,et al. Scalable molecular dynamics with NAMD , 2005, J. Comput. Chem..
[12] Alexander D. MacKerell,et al. Update of the CHARMM all-atom additive force field for lipids: validation on six lipid types. , 2010, The journal of physical chemistry. B.
[13] E. Tajkhorshid,et al. Water access points and hydration pathways in CLC H+/Cl− transporters , 2013, Proceedings of the National Academy of Sciences.
[14] Berrin Tansel,et al. Significance of hydrated radius and hydration shells on ionic permeability during nanofiltration in dead end and cross flow modes , 2006 .
[15] Michael Pusch,et al. Chloride/proton antiporter activity of mammalian CLC proteins ClC-4 and ClC-5 , 2005, Nature.
[16] Klaus Schulten,et al. Mechanism of anionic conduction across ClC. , 2004, Biophysical journal.
[17] T. Jentsch,et al. Residues Important for Nitrate/Proton Coupling in Plant and Mammalian CLC Transporters* , 2009, Journal of Biological Chemistry.
[18] W. L. Jorgensen,et al. Comparison of simple potential functions for simulating liquid water , 1983 .
[19] T. Jentsch. CLC Chloride Channels and Transporters: From Genes to Protein Structure, Pathology and Physiology , 2008 .
[20] Roderick MacKinnon,et al. Gating the Selectivity Filter in ClC Chloride Channels , 2003, Science.
[21] T. Jentsch,et al. Determinants of Anion-Proton Coupling in Mammalian Endosomal CLC Proteins* , 2008, Journal of Biological Chemistry.
[22] A. George,et al. Mechanism of Ion Permeation in Skeletal Muscle Chloride Channels , 1997, The Journal of general physiology.
[23] Stephan Irle,et al. Molecular Simulation of Water and Hydration Effects in Different Environments: Challenges and Developments for DFTB Based Models , 2014, The journal of physical chemistry. B.
[24] T. Jentsch,et al. ClC‐7 is a slowly voltage‐gated 2Cl−/1H+‐exchanger and requires Ostm1 for transport activity , 2011, The EMBO journal.
[25] Thomas L Beck,et al. Proton pathways and H+/Cl− stoichiometry in bacterial chloride transporters , 2007, Proteins.
[26] M. Klein,et al. Exploring the gating mechanism in the ClC chloride channel via metadynamics. , 2006, Journal of molecular biology.
[27] Frederick Dechow,et al. Separation and Purification Techniques in Biotechnology , 1990 .
[28] Carole Williams,et al. Synergism between halide binding and proton transport in a CLC-type exchanger. , 2006, Journal of molecular biology.
[29] Simon Bernèche,et al. Synergistic substrate binding determines the stoichiometry of transport of a prokaryotic H+:Cl− exchanger , 2012, Nature Structural &Molecular Biology.
[30] Merritt Maduke,et al. High-Level Expression, Functional Reconstitution, and Quaternary Structure of a Prokaryotic Clc-Type Chloride Channel , 1999, The Journal of general physiology.
[31] R. Stockbridge,et al. F−/Cl− selectivity in CLCF-type F−/H+ antiporters , 2014, The Journal of general physiology.
[32] T. Jentsch,et al. Permeation and Block of the Skeletal Muscle Chloride Channel, ClC-1, by Foreign Anions , 1998, The Journal of general physiology.
[33] Mary Hongying Cheng,et al. Molecular dynamics investigation of Cl- and water transport through a eukaryotic CLC transporter. , 2012, Biophysical journal.
[34] Emad Tajkhorshid,et al. Revealing an outward-facing open conformational state in a CLC Cl–/H+ exchange transporter , 2016, eLife.
[35] S. Nosé. A unified formulation of the constant temperature molecular dynamics methods , 1984 .
[36] V. Stein,et al. Molecular structure and physiological function of chloride channels. , 2002, Physiological reviews.
[37] Secondary water pore formation for proton transport in a ClC exchanger revealed by an atomistic molecular-dynamics simulation. , 2010, Biophysical journal.
[38] Alexander D. MacKerell,et al. Extending the treatment of backbone energetics in protein force fields: Limitations of gas‐phase quantum mechanics in reproducing protein conformational distributions in molecular dynamics simulations , 2004, J. Comput. Chem..
[39] C. Fahlke,et al. Channel-like slippage modes in the human anion/proton exchanger ClC-4 , 2009, The Journal of general physiology.
[40] Ben Corry,et al. The importance of dehydration in determining ion transport in narrow pores. , 2012, Small.
[41] R. Dutzler,et al. X-ray structure of a ClC chloride channel at 3.0 Å reveals the molecular basis of anion selectivity , 2002, Nature.
[42] U. Ludewig,et al. Analysis of a protein region involved in permeation and gating of the voltage‐gated Torpedo chloride channel ClC‐0. , 1997, The Journal of physiology.
[43] A. George,et al. Pore-forming segments in voltage-gated chloride channels , 1997, Nature.
[44] Liang Feng,et al. Structure of a Eukaryotic CLC Transporter Defines an Intermediate State in the Transport Cycle , 2010, Science.
[45] R. Latorre,et al. Anion permeation in human ClC-4 channels. , 2003, Biophysical journal.
[46] D. Monachello,et al. The nitrate/proton antiporter AtCLCa mediates nitrate accumulation in plant vacuoles , 2006, Nature.
[47] G. Voth,et al. Proton transport pathway in the ClC Cl-/H+ antiporter. , 2009, Biophysical journal.
[48] Tobias Stauber,et al. Cell biology and physiology of CLC chloride channels and transporters. , 2012, Comprehensive Physiology.
[49] K. Kawamura,et al. Effective ionic radii of nitrite and thiocyanate estimated in terms of the Boettcher equation and the Lorentz-Lorenz equation , 1982 .
[50] T. Darden,et al. Particle mesh Ewald: An N⋅log(N) method for Ewald sums in large systems , 1993 .
[51] Christopher Miller,et al. Uncoupling of a CLC Cl-/H+ exchange transporter by polyatomic anions. , 2006, Journal of molecular biology.
[52] K. Gerwert,et al. Proton transfer via a transient linear water-molecule chain in a membrane protein , 2011, Proceedings of the National Academy of Sciences.
[53] Z. Weinberg,et al. Fluoride resistance and transport by riboswitch-controlled CLC antiporters , 2012, Proceedings of the National Academy of Sciences.
[54] S. De Stefano,et al. Extracellular Determinants of Anion Discrimination of the Cl−/H+ Antiporter Protein CLC-5* , 2011, The Journal of Biological Chemistry.
[55] Zasha Weinberg,et al. Widespread Genetic Switches and Toxicity Resistance Proteins for Fluoride , 2012, Science.
[56] C. Fahlke,et al. Anion- and proton-dependent gating of ClC-4 anion/proton transporter under uncoupling conditions. , 2011, Biophysical journal.
[57] R. Stockbridge,et al. Fluoride-dependent interruption of the transport cycle of a CLC Cl−/H+ antiporter , 2013, Nature chemical biology.
[58] C. Wraight,et al. Chance and design--proton transfer in water, channels and bioenergetic proteins. , 2006, Biochimica et biophysica acta.
[59] Gregory A Voth,et al. Computer simulation of explicit proton translocation in cytochrome c oxidase: the D-pathway. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[60] Benoît Roux,et al. Electrostatics of ion stabilization in a ClC chloride channel homologue from Escherichia coli. , 2004, Journal of molecular biology.
[61] Chen Xu,et al. Uncoupling and Turnover in a Cl−/H+ Exchange Transporter , 2007, The Journal of general physiology.
[62] L. M. Espinoza-Fonseca,et al. Microsecond Molecular Simulations Reveal a Transient Proton Pathway in the Calcium Pump. , 2015, Journal of the American Chemical Society.
[63] J Hermans,et al. Hydrophilicity of cavities in proteins , 1996, Proteins.
[64] Anders S. Christensen,et al. DFTB3 Parametrization for Copper: The Importance of Orbital Angular Momentum Dependence of Hubbard Parameters , 2015, Journal of chemical theory and computation.
[65] Klaus Gerwert,et al. Proton binding within a membrane protein by a protonated water cluster. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[66] J. Houtman,et al. Basis of substrate binding and conservation of selectivity in the CLC family of channels and transporters , 2009, Nature Structural &Molecular Biology.
[67] B. Wallace,et al. HOLE: a program for the analysis of the pore dimensions of ion channel structural models. , 1996, Journal of molecular graphics.
[68] Christopher Miller,et al. Intracellular Proton-Transfer Mutants in a CLC Cl−/H+ Exchanger , 2009, The Journal of general physiology.
[69] M. Pusch,et al. Conversion of the 2 Cl−/1 H+ antiporter ClC‐5 in a NO3−/H+ antiporter by a single point mutation , 2009, The EMBO journal.