Acute eosinophilic pneumonia following cigarette smoking: a case report including cigarette-smoking challenge test.

A 21-year-old woman presented with acute progressive dyspnea. Chest computed tomography (CT) revealed diffuse bilateral infiltrates. Based on the results of transbronchial lung biopsy (TBLB) and bronchoalveolar lavage fluid (BALF) and her clinical course, she was diagnosed as having acute eosinophilic pneumonia. We suspected that the disease was related to smoking because she had started smoking ten days before the onset of symptoms. Therefore, a cigarette-smoking challenge test was done with the patient's informed consent. After the challenge, eosinophilic pneumonia was documented by BALF and TBLB findings, which were similar to those detected on admission, without significant radiographic findings.

[1]  M. Fujimura,et al.  In vivo airway eosinophil accumulation induced by polymyxin‐B reduces bronchial responsiveness in guinea pigs , 2001, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[2]  J. Araya,et al.  [Acute eosinophilic pneumonia induced by cigarette smoking: positive lymphocyte stimulation test of a cigarette extract]. , 2000, Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society.

[3]  M. Nakajima,et al.  Acute eosinophilic pneumonia following cigarette smoking. , 2000, Internal medicine.

[4]  S. Miura,et al.  [Acute eosinophilic pneumonia induced by cigarette smoking--a challenge test utilizing another brand of cigarette]. , 2000, Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society.

[5]  K. Nakagome,et al.  [Acute eosinophilic pneumonia induced by cigarette smoking]. , 2000, Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society.

[6]  M. Fujimura,et al.  A case of cigarette smoking-induced acute eosinophilic pneumonia showing tolerance. , 2000, Chest.

[7]  T. Manabe,et al.  Acute eosinophilic pneumonia caused by cigarette smoking. , 2000, Internal medicine.

[8]  M. Fujimura,et al.  Acute eosinophilic pneumonia caused by cigarette smoking. , 2000, Internal medicine.

[9]  N. Miyashita,et al.  [Eosinophilia and cough induced by resumption of cigarette smoking in a beginning smoker recovering from acute respiratory failure]. , 1999, Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society.

[10]  S. Ito,et al.  [Positive response to smoking challenge test in a case of acute eosinophilic pneumonia]. , 1999, Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society.

[11]  M. Fujimura,et al.  Bronchoalveolar lavage cell findings in three types of eosinophilic pneumonia: acute, chronic and drug-induced eosinophilic pneumonia. , 1998, Respiratory medicine.

[12]  Busse,et al.  Mechanisms of acute eosinophilic inflammation in a case of acute eosinophilic pneumonia in a 14‐year‐old girl , 1998, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[13]  Y. Nakahara,et al.  [A clinical study of 5 cases of acute eosinophilic pneumonia--the relationship between beginning to smoke and acute eosinophilic pneumonia]. , 1997, Nihon Kyobu Shikkan Gakkai zasshi.

[14]  N. Miyashita,et al.  Acute Eosinophilic Pneumonia Induced by Cigarrette Smoke , 1997 .

[15]  N. Miyashita,et al.  [Acute eosinophilic pneumonia induced by cigarette smoke]. , 1997, Nihon Kyobu Shikkan Gakkai zasshi.

[16]  E. Pacht,et al.  Acute eosinophilic pneumonia as a reversible cause of noninfectious respiratory failure. , 1989, The New England journal of medicine.