Gastrointestinal and renal involvement in vasculitis: management strategies in Henoch-Schönlein purpura.

The joint pain, inflammation, and painful cutaneous edema of Henoch-Schölein purpura (HSP) are effectively treated with analgesics, nonsteroidal anti-inflammatory agents, and corticosteroids, but the optimal management of HSP-associated gastrointestinal and renal involvement has not yet been determined. The results of mostly anecdotal and uncontrolled studies favor a short course of oral corticosteroids for severe abdominal pain and aggressive immunosuppressive therapy for patients with progressive HSP nephritis.

[1]  P. Niaudet,et al.  Primary IgA nephropathies in children: prognosis and treatment. , 1993, Advances in nephrology from the Necker Hospital.

[2]  C. Glasier,et al.  Henoch-Schonlein syndrome in children: gastrointestinal manifestations. , 1981, AJR. American journal of roentgenology.

[3]  J. Cream,et al.  Schönlein-Henoch purpura in the adult. A study of 77 adults with anaphylactoid or Schönlein-Henoch purpura. , 1970, The Quarterly journal of medicine.