Genetic contributions to transdiagnostic symptom dimensions in patients with major depressive disorder, bipolar disorder, and schizophrenia spectrum disorders

[1]  Michael F. Green,et al.  Mapping genomic loci implicates genes and synaptic biology in schizophrenia , 2022, Nature.

[2]  Dan J Stein,et al.  Genome-wide association study of over 40,000 bipolar disorder cases provides new insights into the underlying biology , 2021, Nature Genetics.

[3]  T. Andlauer,et al.  The genetic basis of major depression , 2021, Psychological Medicine.

[4]  Till F. M. Andlauer,et al.  Identification of transdiagnostic psychiatric disorder subtypes using unsupervised learning , 2021, Neuropsychopharmacology.

[5]  Till F. M. Andlauer,et al.  Clinical and genetic differences between bipolar disorder type 1 and 2 in multiplex families , 2021, Translational Psychiatry.

[6]  E. Fried,et al.  Reviewing the genetics of heterogeneity in depression: operationalizations, manifestations and etiologies , 2020, Human molecular genetics.

[7]  Y. Jossin Reelin Functions, Mechanisms of Action and Signaling Pathways During Brain Development and Maturation , 2020, Biomolecules.

[8]  E. Vassos,et al.  Polygenic risk scores: from research tools to clinical instruments , 2020, Genome Medicine.

[9]  Till F. M. Andlauer,et al.  Polygenic scores for psychiatric disease: from research tool to clinical application , 2020, Medizinische Genetik.

[10]  Matthias J. Müller,et al.  Factor analyses of multidimensional symptoms in a large group of patients with major depressive disorder, bipolar disorder, schizoaffective disorder and schizophrenia , 2020, Schizophrenia Research.

[11]  Xihong Lin,et al.  Operating characteristics of the rank‐based inverse normal transformation for quantitative trait analysis in genome‐wide association studies , 2019, Biometrics.

[12]  H. Stefánsson,et al.  Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression , 2019, Molecular Psychiatry.

[13]  Thomas W. Mühleisen,et al.  Genetic factors influencing a neurobiological substrate for psychiatric disorders , 2019, bioRxiv.

[14]  M. Rietschel,et al.  Associations of schizophrenia risk genes ZNF804A and CACNA1C with schizotypy and modulation of attention in healthy subjects , 2019, Schizophrenia Research.

[15]  D. Geschwind,et al.  Defining the Genetic, Genomic, Cellular, and Diagnostic Architectures of Psychiatric Disorders , 2019, Cell.

[16]  M. Nöthen,et al.  Durchbrüche im Verständnis der molekularen Ursachen psychiatrischer Störungen , 2019, Der Nervenarzt.

[17]  Hunna J. Watson,et al.  Genome wide meta-analysis identifies genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders , 2019, bioRxiv.

[18]  O. Andreassen,et al.  A global overview of pleiotropy and genetic architecture in complex traits , 2019, Nature Genetics.

[19]  S. Cichon,et al.  Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders , 2018, bioRxiv.

[20]  Ariana E. Anderson,et al.  Bifactor Modeling of the Positive and Negative Syndrome Scale: Generalized Psychosis Spans Schizoaffective, Bipolar, and Schizophrenia Diagnoses , 2018, Schizophrenia bulletin.

[21]  T. Ha,et al.  Psychopathologic structure of bipolar disorders: exploring dimensional phenotypes, their relationships, and their associations with bipolar I and II disorders , 2018, Psychological Medicine.

[22]  R. Ophoff,et al.  The characteristics of psychotic features in bipolar disorder , 2018, Psychological Medicine.

[23]  Tilo Kircher,et al.  Neurobiology of the major psychoses: a translational perspective on brain structure and function—the FOR2107 consortium , 2018, European Archives of Psychiatry and Clinical Neuroscience.

[24]  Yang Ni,et al.  Polygenic prediction via Bayesian regression and continuous shrinkage priors , 2018, Nature Communications.

[25]  Till F. M. Andlauer,et al.  A longitudinal approach to biological psychiatric research: The PsyCourse study , 2018, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[26]  Tianxi Cai,et al.  Genome-wide Association Study of Dimensional Psychopathology Using Electronic Health Records , 2018, Biological Psychiatry.

[27]  D. Watson,et al.  HIERARCHICAL TAXONOMY OF PSYCHOPATHOLOGY 1 Running Head: HIERARCHICAL TAXONOMY OF PSYCHOPATHOLOGY A Hierarchical Taxonomy of Psychopathology Can Transform Mental Health Research , 2018 .

[28]  M. Owen,et al.  Examining cognition across the bipolar/schizophrenia diagnostic spectrum. , 2018, Journal of psychiatry & neuroscience : JPN.

[29]  Warren W. Kretzschmar,et al.  Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression , 2017, Nature Genetics.

[30]  D. Posthuma,et al.  Functional mapping and annotation of genetic associations with FUMA , 2017, Nature Communications.

[31]  John P. Rice,et al.  Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes 1 2 Primary , 2018 .

[32]  Russell T. Shinohara,et al.  Common and Dissociable Regional Cerebral Blood Flow Differences Associate with Dimensions of Psychopathology Across Categorical Diagnoses , 2017, Molecular Psychiatry.

[33]  P. Visscher,et al.  10 Years of GWAS Discovery: Biology, Function, and Translation. , 2017, American journal of human genetics.

[34]  R. Baldessarini,et al.  Depression and Mania in Bipolar Disorder , 2017, Current neuropharmacology.

[35]  J. Villén,et al.  Altered CSNK1E, FABP4 and NEFH protein levels in the dorsolateral prefrontal cortex in schizophrenia , 2016, Schizophrenia Research.

[36]  K. Nakajima,et al.  Reelin and Neuropsychiatric Disorders , 2016, Front. Cell. Neurosci..

[37]  M. Birchwood,et al.  Depression and Schizophrenia: Cause, Consequence, or Trans-diagnostic Issue? , 2016, Schizophrenia bulletin.

[38]  Gabor T. Marth,et al.  A global reference for human genetic variation , 2015, Nature.

[39]  Susan L. Rossell,et al.  Auditory verbal hallucinations in bipolar disorder (BD) and major depressive disorder (MDD): A systematic review. , 2015, Journal of affective disorders.

[40]  Joris M. Mooij,et al.  MAGMA: Generalized Gene-Set Analysis of GWAS Data , 2015, PLoS Comput. Biol..

[41]  Carson C Chow,et al.  Second-generation PLINK: rising to the challenge of larger and richer datasets , 2014, GigaScience.

[42]  Daniel H. Mathalon,et al.  Converting positive and negative symptom scores between PANSS and SAPS/SANS , 2014, Schizophrenia Research.

[43]  J. Flint,et al.  The structure of the symptoms of major depression: exploratory and confirmatory factor analysis in depressed Han Chinese women , 2013, Psychological Medicine.

[44]  J. Sweeney,et al.  Phenomenology of first-episode psychosis in schizophrenia, bipolar disorder, and unipolar depression: a comparative analysis. , 2012, Clinical schizophrenia & related psychoses.

[45]  A. Mackinnon,et al.  Depressive symptoms in first episode schizophrenia spectrum disorder , 2012, Schizophrenia Research.

[46]  O. Delaneau,et al.  A linear complexity phasing method for thousands of genomes , 2011, Nature Methods.

[47]  Godfrey Pearlson,et al.  A dimensional approach to the psychosis spectrum between bipolar disorder and schizophrenia: The Schizo-Bipolar Scale , 2011, Schizophrenia Research.

[48]  A. Lussier,et al.  Reelin as a putative vulnerability factor for depression: Examining the depressogenic effects of repeated corticosterone in heterozygous reeler mice , 2011, Neuropharmacology.

[49]  Gail M. Williams,et al.  Psychotic-like experiences in major depression and anxiety disorders: a population-based survey in young adults. , 2011, Schizophrenia bulletin.

[50]  Michael Boehnke,et al.  LocusZoom: regional visualization of genome-wide association scan results , 2010, Bioinform..

[51]  Yun Li,et al.  METAL: fast and efficient meta-analysis of genomewide association scans , 2010, Bioinform..

[52]  Peter Kraft,et al.  Replication in genome-wide association studies. , 2009, Statistical science : a review journal of the Institute of Mathematical Statistics.

[53]  P. Donnelly,et al.  A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies , 2009, PLoS genetics.

[54]  M. Fava,et al.  An Evaluation of the Quick Inventory of Depressive Symptomatology and the Hamilton Rating Scale for Depression: A Sequenced Treatment Alternatives to Relieve Depression Trial Report , 2006, Biological Psychiatry.

[55]  F. Benazzi The relationship of major depressive disorder to bipolar disorder: Continuous or discontinuous? , 2005, Current psychiatry reports.

[56]  R. Emsley,et al.  The factor structure for the Positive and Negative Syndrome Scale (PANSS) in recent-onset psychosis , 2003, Schizophrenia Research.

[57]  S. Fatemi,et al.  Altered levels of Reelin and its isoforms in schizophrenia and mood disorders , 2001, Neuroreport.

[58]  S. Fatemi,et al.  Hippocampal CA4 Reelin-positive neurons , 2000, Molecular Psychiatry.

[59]  N Risch,et al.  The Future of Genetic Studies of Complex Human Diseases , 1996, Science.

[60]  M. Browne,et al.  Alternative Ways of Assessing Model Fit , 1992 .

[61]  P. Bentler,et al.  Comparative fit indexes in structural models. , 1990, Psychological bulletin.

[62]  A. Rush,et al.  The inventory for depressive symptomatology (IDS): Preliminary findings , 1986, Psychiatry Research.

[63]  Y. Benjamini,et al.  Controlling the false discovery rate: a practical and powerful approach to multiple testing , 1995 .

[64]  S. Kay,et al.  The positive and negative syndrome scale (PANSS) for schizophrenia. , 1987, Schizophrenia bulletin.