N-terminal entrance loop of yeast Yps1 and O-glycosylation of substrates are determinant factors controlling the shedding activity of this GPI-anchored endopeptidase

[1]  S. Strahl,et al.  Protein O-mannosylation: what we have learned from baker's yeast. , 2013, Biochimica et biophysica acta.

[2]  Chengchao Xu,et al.  Futile Protein Folding Cycles in the ER Are Terminated by the Unfolded Protein O-Mannosylation Pathway , 2013, Science.

[3]  S. Brunak,et al.  Precision mapping of the human O‐GalNAc glycoproteome through SimpleCell technology , 2013, The EMBO journal.

[4]  S. Brunak,et al.  A Systematic Study of Site-specific GalNAc-type O-Glycosylation Modulating Proprotein Convertase Processing* , 2011, The Journal of Biological Chemistry.

[5]  V. Goder,et al.  Protein O-mannosyltransferases participate in ER protein quality control , 2011, Journal of Cell Science.

[6]  L. Didone,et al.  Extracellular Secretion of Overexpressed Glycosylphosphatidylinositol-Linked Cell Wall Protein Utr2/Crh2p as a Novel Protein Quality Control Mechanism in Saccharomyces cerevisiae , 2010, Eukaryotic Cell.

[7]  I. Pichová,et al.  The crystal structure of the secreted aspartic protease 1 from Candida parapsilosis in complex with pepstatin A. , 2009, Journal of structural biology.

[8]  R. Yada,et al.  Multifunctional aspartic peptidase prosegments. , 2009, New biotechnology.

[9]  R. Huber,et al.  X‐ray structures of Sap1 and Sap5: Structural comparison of the secreted aspartic proteinases from Candida albicans , 2008, Proteins.

[10]  Isabelle Gagnon-Arsenault,et al.  Activation mechanism, functional role and shedding of glycosylphosphatidylinositol‐anchored Yps1p at the Saccharomyces cerevisiae cell surface , 2008, Molecular microbiology.

[11]  D. Krysan,et al.  Cleavage of the signaling mucin Msb2 by the aspartyl protease Yps1 is required for MAPK activation in yeast , 2008, The Journal of cell biology.

[12]  Y. Jigami,et al.  O-mannosylation is required for degradation of the endoplasmic reticulum-associated degradation substrate Gas1*p via the ubiquitin/proteasome pathway in Saccharomyces cerevisiae. , 2007, Journal of biochemistry.

[13]  R. Huber,et al.  The crystal structure of the secreted aspartic proteinase 3 from Candida albicans and its complex with pepstatin A , 2007, Proteins.

[14]  Isabelle Gagnon-Arsenault,et al.  Fungal yapsins and cell wall: a unique family of aspartic peptidases for a distinctive cellular function. , 2006, FEMS yeast research.

[15]  S. Strahl,et al.  Aberrant Processing of the WSC Family and Mid2p Cell Surface Sensors Results in Cell Death of Saccharomyces cerevisiae O-Mannosylation Mutants , 2004, Molecular and Cellular Biology.

[16]  Marc A. Martí-Renom,et al.  Tools for comparative protein structure modeling and analysis , 2003, Nucleic Acids Res..

[17]  Julie D Thompson,et al.  Multiple Sequence Alignment Using ClustalW and ClustalX , 2003, Current protocols in bioinformatics.

[18]  C. Abad-Zapatero,et al.  Candida proteases and their inhibition: prospects for antifungal therapy. , 2001, Current medicinal chemistry.

[19]  J. Sambrook,et al.  Molecular Cloning: A Laboratory Manual , 2001 .

[20]  Y. Bourbonnais,et al.  Production of full-length human pre-elafin, an elastase specific inhibitor, from yeast requires the absence of a functional yapsin 1 (Yps1p) endoprotease. , 2000, Protein expression and purification.

[21]  Y. Loh,et al.  In vivo processing of nonanchored Yapsin 1 (Yap3p). , 2000, Archives of biochemistry and biophysics.

[22]  Y. Loh,et al.  Activation and Processing of Non-anchored Yapsin 1 (Yap3p)* , 1998, The Journal of Biological Chemistry.

[23]  J. Symerský,et al.  High-resolution structure of the extracellular aspartic proteinase from Candida tropicalis yeast. , 1997, Biochemistry.

[24]  M. Gentzsch,et al.  Protein-O-glycosylation in yeast: protein-specific mannosyltransferases. , 1997, Glycobiology.

[25]  D. Y. Thomas,et al.  The Yeast Proprotein Convertase Encoded by YAP3 Is a Glycophosphatidylinositol-anchored Protein That Localizes to the Plasma Membrane (*) , 1995, The Journal of Biological Chemistry.

[26]  T. Blundell,et al.  Comparative protein modelling by satisfaction of spatial restraints. , 1993, Journal of molecular biology.

[27]  Y. Loh,et al.  Purified yeast aspartic protease 3 cleaves anglerfish pro‐somatostatin I and II at di‐ and monobasic sites to generate somatostatin‐14 and ‐28 , 1993, FEBS letters.

[28]  Y. Loh,et al.  Purification and characterization of a paired basic residue-specific yeast aspartic protease encoded by the YAP3 gene. Similarity to the mammalian pro-opiomelanocortin-converting enzyme. , 1993, The Journal of biological chemistry.

[29]  D. Y. Thomas,et al.  Isolation and characterization of S. cerevisiae mutants defective in somatostatin expression: cloning and functional role of a yeast gene encoding an aspartyl protease in precursor processing at monobasic cleavage sites. , 1993, The EMBO journal.

[30]  M. Dante,et al.  Multifunctional yeast high-copy-number shuttle vectors. , 1992, Gene.

[31]  M. Egel-Mitani,et al.  A novel aspartyl protease allowing KEX2‐independent MFα propheromone processing in yeast , 1990 .

[32]  J. Strathern,et al.  Methods in yeast genetics : a Cold Spring Harbor Laboratory course manual , 2005 .

[33]  D. Y. Thomas,et al.  Cleavage of prosomatostatins by the yeast Yap3 and Kex2 endoprotease. , 1994, Biochimie.

[34]  M. Egel-Mitani,et al.  A novel aspartyl protease allowing KEX2-independent MF alpha propheromone processing in yeast. , 1990, Yeast.

[35]  G. Fink,et al.  Laboratory course manual for methods in yeast genetics , 1986 .

[36]  Thomas A. Kunkel,et al.  Rapid and efficient site-specific mutagenesis without phenotypic selection. , 1985, Proceedings of the National Academy of Sciences of the United States of America.