Novel approach to the synthesis of α-alkoxycarbonyl α-aminophosphonic esters based on a facile transformation of phosphoranes to phosphonic esters

Triethoxyphosphoranes 2, generated in situ from oxamates 1, reacted with bromotrimethylsilane to give α-aminophosphonic esters 3 which, in the case of example 13, have been used in a new synthesis of 1-β-methylcarbapenem 14.

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