Quantum dots with silica shells

The present paper introduces to the problems related with the application of silica shells to luminescent semiconductor nanocrystals, especially for bioanalytical applications. Two examples for the preparation of silica shells are presented: First, preparation of a very thin silica layer with simultaneous functionalisation and biological application. Second, a new preparation method for silica shells based on a sol-gel approach. In summary, it is shown, that --- despite of all problems --- high-quality silica coated nanocrystals can be prepared and are well suited for bioanalytical applications.

[1]  Horst Weller,et al.  Ligand design and bioconjugation of colloidal gold nanoparticles. , 2002, Angewandte Chemie.

[2]  Thomas Nann,et al.  Single quantum dots in spherical silica particles. , 2004, Angewandte Chemie.

[3]  Horst Weller,et al.  Biofunctionalization of Silica-Coated CdTe and Gold Nanocrystals , 2002 .

[4]  P. Mulvaney,et al.  Synthesis of Tunable, Highly Luminescent QD‐Glasses Through Sol‐Gel Processing , 2001 .

[5]  A. Alivisatos,et al.  Light-emitting diodes made from cadmium selenide nanocrystals and a semiconducting polymer , 1994, Nature.

[6]  D. Balding,et al.  HLA Sequence Polymorphism and the Origin of Humans , 2006 .

[7]  P. Guyot-Sionnest,et al.  Synthesis and Characterization of Strongly Luminescing ZnS-Capped CdSe Nanocrystals , 1996 .

[8]  S. Nie,et al.  Quantum dot bioconjugates for ultrasensitive nonisotopic detection. , 1998, Science.

[9]  T. Nann,et al.  Monodisperse CdSe nanorods at low temperatures. , 2002, Chemistry.

[10]  Andreas Kornowski,et al.  Highly Luminescent Monodisperse CdSe and CdSe/ZnS Nanocrystals Synthesized in a Hexadecylamine-Trioctylphosphine Oxide-Trioctylphospine Mixture. , 2001, Nano letters.

[11]  Alexander Eychmüller,et al.  Strongly Photoluminescent CdTe Nanocrystals by Proper Surface Modification , 1998 .

[12]  H. Weller,et al.  Study of conduction mechanism and electroluminescence in CdSe/ZnS quantum dot composites , 2003 .

[13]  Alf Mews,et al.  Electroluminescence from isolated CdSe∕ZnS quantum dots in multilayered light-emitting diodes , 2004 .

[14]  Paul Mulvaney,et al.  Silica encapsulation of quantum dots and metal clusters , 2000 .

[15]  Charles F. Zukoski,et al.  Preparation of monodisperse silica particles: control of size and mass fraction , 1988 .

[16]  M. Bawendi,et al.  Synthesis and characterization of nearly monodisperse CdE (E = sulfur, selenium, tellurium) semiconductor nanocrystallites , 1993 .

[17]  Paul Mulvaney,et al.  Synthesis of Nanosized Gold−Silica Core−Shell Particles , 1996 .

[18]  Peter Reiss,et al.  Highly Luminescent CdSe/ZnSe Core/Shell Nanocrystals of Low Size Dispersion , 2002 .

[19]  J. Matthew Mauro,et al.  Self-Assembly of CdSe−ZnS Quantum Dot Bioconjugates Using an Engineered Recombinant Protein , 2000 .

[20]  Christina Graf,et al.  A General Method To Coat Colloidal Particles with Silica , 2003 .

[21]  T. Nann,et al.  Visualizing the self-assembly of tubulin with luminescent nanorods. , 2003, Journal of nanoscience and nanotechnology.

[22]  A. Malko,et al.  Optical gain and stimulated emission in nanocrystal quantum dots. , 2000, Science.

[23]  W. Stöber,et al.  Controlled growth of monodisperse silica spheres in the micron size range , 1968 .

[24]  Shimon Weiss,et al.  Synthesis and Properties of Biocompatible Water-Soluble Silica-Coated CdSe/ZnS Semiconductor Quantum Dots† , 2001 .

[25]  Alexander Eychmüller,et al.  Chemistry and photophysics of thiol-stabilized II-VI semiconductor nanocrystals , 2000 .