A novel microfluidic platform for high-resolution imaging of a three-dimensional cell culture under a controlled hypoxic environment.
暂无分享,去创建一个
Kenichi Funamoto | Roger D Kamm | Choong Kim | R. Kamm | I. Zervantonakis | Yuchun Liu | Choong Kim | Kenichi Funamoto | Christopher J Ochs | Yuchun Liu | Ioannis K Zervantonakis | C. J. Ochs
[1] Ulrike Haessler,et al. Migration dynamics of breast cancer cells in a tunable 3D interstitial flow chamber. , 2012, Integrative biology : quantitative biosciences from nano to macro.
[2] Patrick Ymele-Leki,et al. Fluorescent microparticles for sensing cell microenvironment oxygen levels within 3D scaffolds. , 2009, Biomaterials.
[3] S. A. Stern,et al. Diffusion of Gases in Silicone Polymers: Molecular Dynamics Simulations , 1998 .
[4] Chien-Chung Peng,et al. Generation of oxygen gradients in microfluidic devices for cell culture using spatially confined chemical reactions. , 2011, Lab on a chip.
[5] Alan Wells,et al. 2D protrusion but not motility predicts growth factor–induced cancer cell migration in 3D collagen , 2012, The Journal of cell biology.
[6] Roger D Kamm,et al. A microfluidic platform for studying the effects of small temperature gradients in an incubator environment. , 2008, Biomicrofluidics.
[7] P. Walczak,et al. Hypoxia increases breast cancer cell-induced lymphatic endothelial cell migration. , 2008, Neoplasia.
[8] Andrew Burgess,et al. Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance , 2010, Proceedings of the National Academy of Sciences.
[9] Lionel Flamant,et al. Anti-apoptotic role of HIF-1 and AP-1 in paclitaxel exposed breast cancer cells under hypoxia , 2010, Molecular Cancer.
[10] R. Misra,et al. Biomaterials , 2008 .
[11] Hanry Yu,et al. A practical guide to microfluidic perfusion culture of adherent mammalian cells. , 2007, Lab on a chip.
[12] Shuichi Takayama,et al. Quantitative measurement and control of oxygen levels in microfluidic poly(dimethylsiloxane) bioreactors during cell culture , 2007, Biomedical microdevices.
[13] David T. Eddington,et al. Modulating Temporal and Spatial Oxygenation over Adherent Cellular Cultures , 2009, PloS one.
[14] A. Elias,et al. Finite element analysis of oxygen transport in microfluidic cell culture devices with varying channel architectures, perfusion rates, and materials , 2011 .
[15] Roger D. Kamm,et al. Microfluidic Platforms for Studies of Angiogenesis, Cell Migration, and Cell–Cell Interactions , 2010, Annals of Biomedical Engineering.
[16] Leonard I Zon,et al. Cell stem cell. , 2007, Cell stem cell.
[17] Roger D Kamm,et al. Microfluidic devices for studying heterotypic cell-cell interactions and tissue specimen cultures under controlled microenvironments. , 2011, Biomicrofluidics.
[18] Y. Sakai,et al. Low O2 metabolism of HepG2 cells cultured at high density in a 3D microstructured scaffold , 2009, Biomedical microdevices.
[19] W. Koros,et al. Gas transport in polymers based on bisphenol‐A , 1988 .
[20] Dr. Andreas von Deimling. Neoplasia , 1997, Laboratory investigation; a journal of technical methods and pathology.
[21] R. Hill,et al. Graded hypoxia modulates the invasive potential of HT1080 fibrosarcoma and MDA MB231 carcinoma cells , 2008, Clinical & Experimental Metastasis.
[22] Todd Thorsen,et al. Development of an integrated microfluidic platform for dynamic oxygen sensing and delivery in a flowing medium. , 2005, Lab on a chip.
[23] R. Kamm,et al. Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function , 2012, Proceedings of the National Academy of Sciences.
[24] Matthew H. M. Lim,et al. Perfused multiwell plate for 3D liver tissue engineering. , 2010, Lab on a chip.
[25] D. Eddington,et al. Oxygen sensitive microwells. , 2010, Lab on a chip.
[26] Richard P. Hill,et al. The hypoxic tumour microenvironment and metastatic progression , 2004, Clinical & Experimental Metastasis.
[27] O. Geschke,et al. Microfluidic dissolved oxygen gradient generator biochip as a useful tool in bacterial biofilm studies. , 2010, Lab on a chip.
[28] P. Vaupel,et al. Tumor hypoxia: definitions and current clinical, biologic, and molecular aspects. , 2001, Journal of the National Cancer Institute.
[29] Alfredo Quiñones-Hinojosa,et al. Oxygen in stem cell biology: a critical component of the stem cell niche. , 2010, Cell stem cell.
[30] David T Eddington,et al. Oxygen gradients for open well cellular cultures via microfluidic substrates. , 2010, Lab on a chip.
[31] C. Tanford. Macromolecules , 1994, Nature.
[32] C. White,et al. Limitations to oxygen diffusion and equilibration in in vitro cell exposure systems in hyperoxia and hypoxia. , 2001, American journal of physiology. Lung cellular and molecular physiology.
[33] T. Moriya,et al. Effects of Oxygen Concentration on the Proliferation and Differentiation of Mouse Neural Stem Cells In Vitro , 2008, Cellular and Molecular Neurobiology.
[34] Paolo A Netti,et al. Oxygen consumption of chondrocytes in agarose and collagen gels: a comparative analysis. , 2008, Biomaterials.
[35] Mark E. Polinkovsky,et al. Fine temporal control of the medium gas content and acidity and on-chip generation of series of oxygen concentrations for cell cultures. , 2009, Lab on a chip.
[36] R. Hill,et al. Acute (cyclic) hypoxia enhances spontaneous metastasis of KHT murine tumors. , 2001, Cancer research.
[37] Farshid Guilak,et al. An In Vitro System to Evaluate the Effects of Ischemia on Survival of Cells Used for Cell Therapy , 2007, Annals of Biomedical Engineering.
[38] M. Russo,et al. Role of hypoxia and autophagy in MDA‐MB‐231 invasiveness , 2010, Journal of cellular physiology.
[39] Raymond H. W. Lam,et al. Culturing Aerobic and Anaerobic Bacteria and Mammalian Cells with a Microfluidic Differential Oxygenator , 2009, Analytical chemistry.
[40] L. Griffith,et al. Transport‐mediated angiogenesis in 3D epithelial coculture , 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[41] R. Blasberg,et al. Real-Time Imaging of HIF-1α Stabilization and Degradation , 2009, PloS one.
[42] Roger D Kamm,et al. A high-throughput microfluidic assay to study neurite response to growth factor gradients. , 2011, Lab on a chip.
[43] Gordana Vunjak-Novakovic,et al. Perfusion improves tissue architecture of engineered cardiac muscle. , 2002, Tissue engineering.
[44] Vernella Vickerman,et al. Design, fabrication and implementation of a novel multi-parameter control microfluidic platform for three-dimensional cell culture and real-time imaging. , 2008, Lab on a chip.
[45] H. Redmond,et al. Hypoxia increases the metastatic ability of breast cancer cells via upregulation of CXCR4 , 2010, BMC Cancer.
[46] Nadine Kabbani,et al. Enhanced Proliferation, Survival, and Dopaminergic Differentiation of CNS Precursors in Lowered Oxygen , 2000, The Journal of Neuroscience.
[47] Tharathorn Rimchala,et al. Surface‐Treatment‐Induced Three‐Dimensional Capillary Morphogenesis in a Microfluidic Platform , 2009, Advanced materials.
[48] R. Motzer,et al. High-dose chemotherapy and stem cell transplantation for advanced testicular cancer , 2011, Expert review of anticancer therapy.
[49] P Vaupel,et al. Oxygenation of human tumors: evaluation of tissue oxygen distribution in breast cancers by computerized O2 tension measurements. , 1991, Cancer research.
[50] William J. Polacheck,et al. Interstitial flow influences direction of tumor cell migration through competing mechanisms , 2011, Proceedings of the National Academy of Sciences.
[51] Mark E. Polinkovsky,et al. Generation of oxygen gradients with arbitrary shapes in a microfluidic device. , 2010, Lab on a chip.
[52] Ali Borhan,et al. Three-Dimensional Simulations of Reactive Gas Uptake in Single Airway Bifurcations , 2007, Annals of Biomedical Engineering.
[53] J. Bussink,et al. Optical Sensor-Based Oxygen Tension Measurements Correspond with Hypoxia Marker Binding in Three Human Tumor Xenograft Lines , 2000, Radiation research.
[54] Tim David,et al. Patterning, integration and characterisation of polymer optical oxygen sensors for microfluidic devices. , 2008, Lab on a chip.
[55] 宁北芳,et al. 疟原虫var基因转换速率变化导致抗原变异[英]/Paul H, Robert P, Christodoulou Z, et al//Proc Natl Acad Sci U S A , 2005 .