Introduction to Clinical Research Informatics

This chapter provides essential definitions and overviews important ­constructs and methods within the emerging subdomain of clinical research ­informatics. The chapter also highlights theoretical and practical contributions from other disciplines. This chapter sets the tone and scope for the text, highlights ­important themes, and describes the content and organization of chapters.

[1]  H. Atkins.  The Three Pillars of Clinical Research* , 1958 .

[2]  J W Bellville,et al.  The use of computers in clinical trials. , 1967, British journal of anaesthesia.

[3]  William W. Stead,et al.  Features of TMR for a Successful Clinical and Research Database , 1982 .

[4]  Blois Ms.  Medical records and clinical databases: what is the difference? , 1984 .

[5]  E. Mansour,et al.  Barriers to clinical trials: Part III: Knowledge and attitudes of health care providers , 1994, Cancer.

[6]  E H Shortliffe,et al.  Computer-based screening of patients with HIV/AIDS for clinical-trial eligibility. , 1995, The Online journal of current clinical trials.

[7]  W M Tierney,et al.  Application of Information Technology: Pilot Study of a Point-of-use Decision Support Tool for Cancer Clinical Trials Eligibility , 1999, J. Am. Medical Informatics Assoc..

[8]  E. Shortliffe,et al.  Biomedical informatics : computer applications in health care and biomedicine , 2001 .

[9]  Lawrence M. Fagan,et al.  Medical informatics: computer applications in health care and biomedicine (Health informatics) , 2003 .

[10]  Dan Mayer,et al.  Essential Evidence-Based Medicine , 2004 .

[11]  A. Bacchieri,et al.  Fundamentals of clinical research , 2007 .

[12]  Philip R. O. Payne,et al.  Clinical research informatics: challenges, opportunities and definition for an emerging domain. , 2009, Journal of the American Medical Informatics Association : JAMIA.

[13]  Charles P. Friedman,et al.  Viewpoint Paper: A "Fundamental Theorem" of Biomedical Informatics , 2009, J. Am. Medical Informatics Assoc..

[14]  A. Bacchieri,et al.  Fundamentals of Clinical Research: Bridging Medicine, Statistics and Operations , 2014 .

[15]  William K. Barnett,et al.  The Emerging Role of the Chief Research Informatics Officer in Academic Health Centers , 2017, Applied Clinical Informatics.