Vibration analysis of the reactor assembly components of 500 MWe Prototype Fast Breeder Reactor (PFBR) is presented. The vibration response of primary pump as well as dynamic forces developed at its supports are predicted numerically. The stiffness properties of hydrostatic bearing are determined by formulating and solving governing fluid and structural mechanics equations. The dynamic forces exerted by pump are used as input data for the dynamic response of reactor assembly components, mainly inner vessel, thermal baffle and control plug. Dynamic response of reactor assembly components is also predicted for the pressure fluctuations caused by sodium free level oscillations. Thermal baffle (weir shell) which is subjected to fluid forces developed at the associated sodium free levels is analysed by formulating and solving a set of non-linear equations for fluids, structures and fluid structure interaction (FSI). The control rod drive mechanism is analysed for response under flow induced forces on the parts subjected to cross flow in the zone just above the core top, taking into account FSI between sheaths of control & safety rod and absorber pin bundle. Based on the analysis results, it is concluded that the reactor assembly internals are free from any risk of mechanical as well as flow induced vibrations.