Majority of symptoms in esophageal reflux PPI non‐responders are not related to reflux

Genesis of persistent gastro‐esophageal reflux symptoms despite proton pump inhibitor (PPI) therapy is not fully understood. We aimed at determining reflux patterns on 24‐h pH‐impedance monitoring performed on PPI and correlating impedance patterns and symptom occurrence in PPI non‐responders.

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