Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

[1]  N. Buckley,et al.  Paracetamol (acetaminophen) poisoning. , 2004, Clinical evidence.

[2]  S. Müller,et al.  The double life of HMGB1 chromatin protein: architectural factor and extracellular signal , 2001 .

[3]  V. Fadok,et al.  Differential Effects of Apoptotic Versus Lysed Cells on Macrophage Production of Cytokines: Role of Proteases1 , 2001, The Journal of Immunology.

[4]  R. Scott,et al.  Phagocytosis and clearance of apoptotic cells is mediated by MER , 2001, Nature.

[5]  S. Müller,et al.  The High Mobility Group (Hmg) Boxes of the Nuclear Protein Hmg1 Induce Chemotaxis and Cytoskeleton Reorganization in Rat Smooth Muscle Cells , 2001, The Journal of cell biology.

[6]  M. Bustin Revised nomenclature for high mobility group (HMG) chromosomal proteins. , 2001, Trends in biochemical sciences.

[7]  Tom Misteli,et al.  Dynamic binding of histone H1 to chromatin in living cells , 2000, Nature.

[8]  K. Tracey,et al.  High Mobility Group 1 Protein (Hmg-1) Stimulates Proinflammatory Cytokine Synthesis in Human Monocytes , 2000, The Journal of experimental medicine.

[9]  M. Beltrame,et al.  Upwardly mobile proteins , 2000, EMBO reports.

[10]  A. Lentsch,et al.  Regulation of liver inflammatory injury by signal transducer and activator of transcription-6. , 2000, The American journal of pathology.

[11]  T. Misteli,et al.  High mobility of proteins in the mammalian cell nucleus , 2000, Nature.

[12]  A. Farhood,et al.  The hepatic inflammatory response after acetaminophen overdose: role of neutrophils. , 2000, Toxicological sciences : an official journal of the Society of Toxicology.

[13]  Michael Bustin,et al.  Regulation of DNA-Dependent Activities by the Functional Motifs of the High-Mobility-Group Chromosomal Proteins , 1999, Molecular and Cellular Biology.

[14]  K. Tracey,et al.  HMG-1 as a late mediator of endotoxin lethality in mice. , 1999, Science.

[15]  A. Aguzzi,et al.  The lack of chromosomal protein Hmg1 does not disrupt cell growth but causes lethal hypoglycaemia in newborn mice , 1999, Nature Genetics.

[16]  R. Voll,et al.  Impaired phagocytosis of apoptotic cell material by monocyte-derived macrophages from patients with systemic lupus erythematosus. , 1998, Arthritis and rheumatism.

[17]  J. Savill,et al.  Apoptosis: The importance of being eaten , 1998, Cell Death and Differentiation.

[18]  S. Nagata,et al.  A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD , 1998, Nature.

[19]  G. Längst,et al.  High Mobility Group 1 Protein Is Not Stably Associated with the Chromosomes of Somatic Cells , 1997, The Journal of cell biology.

[20]  M. Helmer-Citterich,et al.  HMG1 interacts with HOX proteins and enhances their DNA binding and transcriptional activation. , 1996, The EMBO journal.

[21]  A. Wolffe,et al.  Differential association of HMG1 and linker histones B4 and H1 with dinucleosomal DNA: structural transitions and transcriptional repression. , 1996, The EMBO journal.

[22]  A. Wolffe,et al.  Evidence for a shared structural role for HMG1 and linker histones B4 and H1 in organizing chromatin. , 1996, The EMBO journal.

[23]  J. Chen,et al.  The Receptor for Advanced Glycation End Products (RAGE) Is a Cellular Binding Site for Amphoterin , 1995, The Journal of Biological Chemistry.

[24]  P. T. Speakman,et al.  Trypsin Inhibition by Phenylmethylsulphonylfluoride with Reduced Wool as Substrate , 1966, Nature.