Development of Vaginal Pseudoaneurysm 3 Years after Cesarean Section Possibly Induced by Anticoagulant and Antiplatelet Therapies

Pseudoaneurysms generally develop when an arterial puncture site is inadequately sealed. We encountered a case of vaginal pseudoaneurysm that developed 3 years after cesarean section in a 35-year-old gravida 7 para 4 woman who was prescribed with anticoagulant and antiplatelet drugs after surgeries for ventricular septal defect and aortic valve replacement. Pelvic computed tomography scan revealed a large mass, which showed a dappled contrast filling on the arterial phase, located in the posterior vaginal wall. The vaginal pseudoaneurysm was completely occluded by embolization of the left vaginal artery. Anticoagulation and antiplatelet therapies can be potential causes of spontaneous pseudoaneurysm rupture. Extrauterine pseudoaneurysm has a long period of time between cesarean section and pseudoaneurysm discovery. Considering that pseudoaneurysm shows different clinical features for each patient, we should always consider pseudoaneurysm when we assess a patient with postpartum hemorrhage.

[1]  S. Matsubara,et al.  Letter to ‘Uterine artery pseudoaneurysm bleeding one decade after caesarean section: A case report’: Pseudoaneurysm anywhere and anytime , 2017, The journal of obstetrics and gynaecology research.

[2]  L. Johannesson,et al.  Uterine artery pseudoaneurysm bleeding one decade after caesarean section: A case report , 2017, The journal of obstetrics and gynaecology research.

[3]  T. Kuwata,et al.  Uterine artery pseudoaneurysm: its occurrence after non-traumatic events, and possibility of "without embolization" strategy. , 2016, European journal of obstetrics, gynecology, and reproductive biology.

[4]  M. Shibuya,et al.  Rupture of pseudoaneurysm of the superficial femoral artery over four years after self-expandable nitinol stent implantation. , 2015, Journal of cardiology cases.

[5]  G. Bonatti,et al.  Anticoagulation Therapy for Postoperative Deep Vein Thrombosis Coupled with Pulmonary Embolism: A Potential Trigger for Delayed Popliteal Artery Injury Presentation after Total Knee Arthroplasty , 2013, Phlebology.

[6]  A. Dohan,et al.  Postpartum Hemorrhage Resulting from Pelvic Pseudoaneurysm: A Retrospective Analysis of 588 Consecutive Cases Treated by Arterial Embolization , 2013, CardioVascular and Interventional Radiology.

[7]  I. Konishi,et al.  Secondary postpartum hemorrhage due to uterine artery pseudoaneurysm rupture in von Willebrand disease , 2011, The journal of obstetrics and gynaecology research.

[8]  Y. Taketani,et al.  Uterine artery pseudoaneurysm after cesarean section: case report and literature review. , 2010, Journal of minimally invasive gynecology.

[9]  Mitsuaki Suzuki,et al.  Asymptomatic uterine artery pseudoaneurysm after cesarean section , 2010, The journal of obstetrics and gynaecology research.

[10]  I. Loftus,et al.  Post-traumatic pelvic pseudoaneurysm and arterio-venous fistula: combined endovascular and surgical approach. , 2008, European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.

[11]  B. Çil,et al.  Late Postpartum Hemorrhage Due to von Willebrand Disease Managed With Uterine Artery Embolization , 2008, Obstetrics and gynecology.

[12]  B. Rubin,et al.  Spontaneous closure of selected iatrogenic pseudoaneurysms and arteriovenous fistulae. , 1997, Journal of vascular surgery.

[13]  D. Baim,et al.  A prospective study of the clinical outcome of femoral pseudoaneurysms and arteriovenous fistulas induced by arterial puncture. , 1993, Journal of vascular surgery.