Validating administrative data for the detection of adverse events in older hospitalized patients

Older hospitalized patients are at risk of experiencing adverse events including, but not limited to, hospital-acquired pressure ulcers, fall-related injuries, and adverse drug events. A significant challenge in monitoring and managing adverse events is lack of readily accessible information on their occurrence. Purpose The objective of this retrospective cross-sectional study was to validate diagnostic codes for pressure ulcers, fall-related injuries, and adverse drug events found in routinely collected administrative hospitalization data. Methods All patients 65 years of age or older discharged between April 1, 2009 and March 31, 2011 from a provincial academic health sciences center in Canada were eligible for inclusion in the validation study. For each of the three types of adverse events, a random sample of 50 patients whose records were positive and 50 patients whose records were not positive for an adverse event was sought for review in the validation study (n=300 records in total). A structured health record review was performed independently by two health care providers with experience in geriatrics, both of whom were unaware of the patient’s status with respect to adverse event coding. A physician reviewed 40 records (20 reviewed by each health care provider) to establish interrater agreement. Results A total of 39 pressure ulcers, 56 fall-related injuries, and 69 adverse drug events were identified through health record review. Of these, 34 pressure ulcers, 54 fall-related injuries, and 47 adverse drug events were also identified in administrative data. Overall, the diagnostic codes for adverse events had a sensitivity and specificity exceeding 0.67 (95% confidence interval [CI]: 0.56–0.99) and 0.89 (95% CI: 0.72–0.99), respectively. Conclusion It is feasible and valid to identify pressure ulcers, fall-related injuries, and adverse drug events in older hospitalized patients using routinely collected administrative hospitalization data. The information is relatively inexpensive and easy to access with no impact on clinical staff.

[1]  E. Peterson,et al.  Falls, aging, and disability. , 2010, Physical medicine and rehabilitation clinics of North America.

[2]  N. MacKinnon,et al.  Demystifying medication safety: making sense of the terminology. , 2006, Research in social & administrative pharmacy : RSAP.

[3]  M. Beers,et al.  Clinical pharmacology in an aging population , 1998, Clinical pharmacology and therapeutics.

[4]  P. Kolh,et al.  Validation of Hospital Administrative Dataset for adverse event screening , 2010, Quality and Safety in Health Care.

[5]  S. Sheps,et al.  The Canadian Adverse Events Study: the incidence of adverse events among hospital patients in Canada , 2004, Canadian Medical Association Journal.

[6]  P. Rochon,et al.  Preventing Pressure Ulcers: A Systematic Review , 2007 .

[7]  Vicki L Burt,et al.  Prescription drug use continues to increase: U.S. prescription drug data for 2007-2008. , 2010, NCHS data brief.

[8]  Andrew Worster,et al.  Advanced statistics: understanding medical record review (MRR) studies. , 2004, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

[9]  R J Lilford,et al.  Organizing patient safety research to identify risks and hazards , 2003, Quality & safety in health care.

[10]  P. Mobily,et al.  Iatrogenesis in the elderly. Factors of immobility. , 1991, Journal of gerontological nursing.

[11]  W. Baine,et al.  The Agency for Healthcare Research and Quality , 2006, Italian Journal of Public Health.

[12]  Jürgen Stausberg,et al.  ICD-10 codes used to identify adverse drug events in administrative data: a systematic review , 2013, J. Am. Medical Informatics Assoc..

[13]  P. Barach,et al.  Reporting and preventing medical mishaps: lessons from non-medical near miss reporting systems , 2000, BMJ : British Medical Journal.

[14]  C. Vincent,et al.  What is known about adverse events in older medical hospital inpatients? A systematic review of the literature. , 2013, International journal for quality in health care : journal of the International Society for Quality in Health Care.

[15]  K. Buckwalter,et al.  Iatrogenesis in the elderly. Drug-related problems. , 1991, Journal of gerontological nursing.

[16]  R. Thomson,et al.  What can we learn about patient safety from information sources within an acute hospital: a step on the ladder of integrated risk management? , 2008, Quality & Safety in Health Care.

[17]  Claudia R Campbell,et al.  A comparison of hospital adverse events identified by three widely used detection methods. , 2009, International journal for quality in health care : journal of the International Society for Quality in Health Care.

[18]  Christianna S. Williams,et al.  The effect of falls and fall injuries on functioning in community-dwelling older persons. , 1998, The journals of gerontology. Series A, Biological sciences and medical sciences.

[19]  T. Brennan,et al.  Incidence and types of adverse events and negligent care in Utah and Colorado. , 2000, Medical care.

[20]  L. Kelley,et al.  Iatrogenesis in the elderly. Impaired skin integrity. , 1991, Journal of gerontological nursing.

[21]  Christianna S. Williams,et al.  Falls, injuries due to falls, and the risk of admission to a nursing home. , 1997, The New England journal of medicine.

[22]  A. Lalonde Canadian Institute for Health Information. , 1994, Canadian journal of medical technology.

[23]  T. Brennan,et al.  The nature of adverse events in hospitalized patients. Results of the Harvard Medical Practice Study II. , 1991, The New England journal of medicine.

[24]  Hude Quan,et al.  Validity of AHRQ patient safety indicators derived from ICD-10 hospital discharge abstract data (chart review study) , 2013, BMJ Open.

[25]  L. Leape,et al.  THE NATURE AND EXTENT OF MEDICAL INJURY IN OLDER PATIENTS , 2000 .

[26]  Anna Ehrenberg,et al.  Accuracy, completeness and comprehensiveness of information on pressure ulcers recorded in the patient record. , 2013, Scandinavian journal of caring sciences.

[27]  John R. Meurer,et al.  Medical Injury Identification Using Hospital Discharge Data , 2005 .

[28]  Wu Xu,et al.  Using ICD-9-CM Codes in Hospital Claims Data to Detect Adverse Events in Patient Safety Surveillance , 2008 .

[29]  J. Posnett,et al.  The cost of pressure ulcers in the UK. , 2004, Age and ageing.

[30]  Dan Osterweil,et al.  Iatrogenic Illness in Hospitalized Elderly People , 1992, Journal of the American Geriatrics Society.

[31]  D. Berlowitz,et al.  Geriatric Syndromes as Outcome Measures of Hospital Care: Can Administrative Data Be Used? , 1999, Journal of the American Geriatrics Society.

[32]  E. Lesaffre,et al.  Adverse outcomes in Belgian acute hospitals: retrospective analysis of the national hospital discharge dataset. , 2006, International journal for quality in health care : journal of the International Society for Quality in Health Care.

[33]  D. Bates,et al.  Relationship between medication errors and adverse drug events , 1995, Journal of General Internal Medicine.

[34]  Jürgen Stausberg,et al.  Evaluating adverse drug event reporting in administrative data from emergency departments: a validation study , 2013, BMC Health Services Research.

[35]  Jürgen Stausberg,et al.  Drug-related admissions and hospital-acquired adverse drug events in Germany: a longitudinal analysis from 2003 to 2007 of ICD-10-coded routine data , 2011, BMC health services research.

[36]  M. Creditor Hazards of Hospitalization of the Elderly , 1993, Annals of Internal Medicine.

[37]  G. Kovacs,et al.  The association between a prolonged stay in the emergency department and adverse events in older patients admitted to hospital: a retrospective cohort study , 2011, Quality and Safety in Health Care.

[38]  J. Gerberding,et al.  Fatalities and injuries from falls among older adults--United States, 1993-2003 and 2001-2005. , 2006, MMWR. Morbidity and mortality weekly report.

[39]  J. Morse Enhancing the safety of hospitalization by reducing patient falls. , 2002, American journal of infection control.

[40]  Melissa J. Krauss,et al.  Characteristics and circumstances of falls in a hospital setting , 2004, Journal of General Internal Medicine.