Concordant Regulation of Translation and mRNA Abundance for Hundreds of Targets of a Human microRNA
暂无分享,去创建一个
David G Hendrickson | P. Brown | J. Myers | J. Ferrell | D. Herschlag | Heather L McCullough | Daniel J Hogan | Daniel J. Hogan | Heather L Mccullough
[1] G. Hannon,et al. Control of translation and mRNA degradation by miRNAs and siRNAs. , 2006, Genes & development.
[2] D. Bartel. MicroRNAs Genomics, Biogenesis, Mechanism, and Function , 2004, Cell.
[3] Colin N. Dewey,et al. Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures , 2007, Nature.
[4] M. Wormington. Unmasking the role of the 3' UTR in the cytoplasmic polyadenylation and translational regulation of maternal mRNAs. , 1994, BioEssays : news and reviews in molecular, cellular and developmental biology.
[5] V. Ambros,et al. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14 , 1993, Cell.
[6] S. Peltz,et al. Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells. , 1996, Annual review of biochemistry.
[7] Yi Wen Kong,et al. How do microRNAs regulate gene expression? , 2008, Biochemical Society transactions.
[8] G. Meister,et al. Identification of Human microRNA Targets From Isolated Argonaute Protein Complexes , 2007, RNA biology.
[9] B. Cullen,et al. Sequence requirements for micro RNA processing and function in human cells. , 2003, RNA.
[10] John G Doench,et al. Comparison of siRNA-induced off-target RNA and protein effects. , 2007, RNA.
[11] H. Ruohola-Baker,et al. Stem cell division is regulated by the microRNA pathway , 2005, Nature.
[12] K. Lindblad-Toh,et al. Systematic discovery of regulatory motifs in human promoters and 3′ UTRs by comparison of several mammals , 2005, Nature.
[13] R. Contreras,et al. The 3' untranslated region of the human interferon-beta mRNA has an inhibitory effect on translation. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[14] Roy Parker,et al. Computational analysis of miRNA-mediated repression of translation: implications for models of translation initiation inhibition. , 2008, RNA.
[15] Daniel Herschlag,et al. Systematic Identification of mRNAs Recruited to Argonaute 2 by Specific microRNAs and Corresponding Changes in Transcript Abundance , 2008, PloS one.
[16] G. Shaw,et al. Translational blockade imposed by cytokine-derived UA-rich sequences. , 1989, Science.
[17] G. Galili,et al. Translational regulation of human beta interferon mRNA: association of the 3' AU-rich sequence with the poly(A) tail reduces translation efficiency in vitro , 1993, Molecular and cellular biology.
[18] E. Moss,et al. Two genetic circuits repress the Caenorhabditis elegans heterochronic gene lin-28 after translation initiation. , 2002, Developmental biology.
[19] Robert B. Russell,et al. Principles of MicroRNATarget Recognition , 2005 .
[20] K. Gunsalus,et al. Combinatorial microRNA target predictions , 2005, Nature Genetics.
[21] T. Rana,et al. Translation Repression in Human Cells by MicroRNA-Induced Gene Silencing Requires RCK/p54 , 2006, PLoS biology.
[22] M. Coutts,et al. Nuclease activity associated with mammalian mRNA in its native state: possible basis for selectivity in mRNA decay , 1990, Molecular and cellular biology.
[23] C. Burge,et al. Most mammalian mRNAs are conserved targets of microRNAs. , 2008, Genome research.
[24] A. Pasquinelli,et al. Uncoupling of lin-14 mRNA and protein repression by nutrient deprivation in Caenorhabditis elegans. , 2009, RNA.
[25] V. Ambros,et al. An Extensive Class of Small RNAs in Caenorhabditis elegans , 2001, Science.
[26] Peer Bork,et al. Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing. , 2007, Genes & development.
[27] T. Nilsen,et al. Mechanisms of microRNA‐mediated gene regulation , 2007, Trends in genetics : TIG.
[28] R. Russell,et al. Principles of MicroRNA–Target Recognition , 2005, PLoS biology.
[29] E. Miska,et al. MicroRNA functions in animal development and human disease , 2005, Development.
[30] Roy Parker,et al. Mutations in Translation Initiation Factors Lead to Increased Rates of Deadenylation and Decapping of mRNAs inSaccharomyces cerevisiae , 1999, Molecular and Cellular Biology.
[31] P. Bork,et al. mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes. , 2006, Genes & development.
[32] Eric J Wagner,et al. Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. , 2002, Molecular cell.
[33] R. Bachvarova. A maternal tail of poly(a): The long and the short of it , 1992, Cell.
[34] M. Wormington. Poly(A) and translation: development control. , 1993, Current opinion in cell biology.
[35] Shengyun Fang,et al. Mdm2 Is a RING Finger-dependent Ubiquitin Protein Ligase for Itself and p53* , 2000, The Journal of Biological Chemistry.
[36] N. Caruccio,et al. Purification of a human polyribosome-associated 3' to 5' exoribonuclease. , 1994, The Journal of biological chemistry.
[37] F. Slack,et al. Temporal pattern formation by heterochronic genes. , 1997, Annual review of genetics.
[38] Roy Parker,et al. General Translational Repression by Activators of mRNA Decapping , 2005, Cell.
[39] Megan F. Cole,et al. Connecting microRNA Genes to the Core Transcriptional Regulatory Circuitry of Embryonic Stem Cells , 2008, Cell.
[40] Anton J. Enright,et al. MicroRNA targets in Drosophila , 2003, Genome Biology.
[41] H. Yasuda,et al. N-Terminally extended human ubiquitin-conjugating enzymes (E2s) mediate the ubiquitination of RING-finger proteins, ARA54 and RNF8. , 2001, European journal of biochemistry.
[42] M. Kozak,et al. Faulty old ideas about translational regulation paved the way for current confusion about how microRNAs function. , 2008, Gene.
[43] J. Castle,et al. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs , 2005, Nature.
[44] Nicholas T. Ingolia,et al. Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling , 2009, Science.
[45] D. Gallie. The cap and poly(A) tail function synergistically to regulate mRNA translational efficiency. , 1991, Genes & development.
[46] Min Han,et al. The developmental timing regulator AIN-1 interacts with miRISCs and may target the argonaute protein ALG-1 to cytoplasmic P bodies in C. elegans. , 2005, Molecular cell.
[47] R Parker,et al. Turnover mechanisms of the stable yeast PGK1 mRNA , 1995, Molecular and cellular biology.
[48] P. Brown,et al. Transcriptional Program Induced by Wnt Protein in Human Fibroblasts Suggests Mechanisms for Cell Cooperativity in Defining Tissue Microenvironments , 2007, PloS one.
[49] Christina Backes,et al. GeneTrail—advanced gene set enrichment analysis , 2007, Nucleic Acids Res..
[50] Anton J. Enright,et al. Zebrafish MiR-430 Promotes Deadenylation and Clearance of Maternal mRNAs , 2006, Science.
[51] Zhenyu Xuan,et al. A biochemical approach to identifying microRNA targets , 2007, Proceedings of the National Academy of Sciences.
[52] David I. K. Martin,et al. MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly(A) tail function. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[53] Kaleb M. Pauley,et al. Detection of the argonaute protein Ago2 and microRNAs in the RNA induced silencing complex (RISC) using a monoclonal antibody. , 2006, Journal of immunological methods.
[54] T. Tuschl,et al. The Human DiGeorge Syndrome Critical Region Gene 8 and Its D. melanogaster Homolog Are Required for miRNA Biogenesis , 2004, Current Biology.
[55] M. Kiriakidou,et al. An mRNA m7G Cap Binding-like Motif within Human Ago2 Represses Translation , 2007, Cell.
[56] Matthias W. Hentze,et al. Drosophila miR2 induces pseudo-polysomes and inhibits translation initiation , 2007, Nature.
[57] P. Walter,et al. Ribosome pausing and stacking during translation of a eukaryotic mRNA. , 1988, The EMBO journal.
[58] Takayuki Murata,et al. MicroRNA Inhibition of Translation Initiation in Vitro by Targeting the Cap-Binding Complex eIF4F , 2007, Science.
[59] C. Burge,et al. Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA Targets , 2005, Cell.
[60] Roy Parker,et al. Decapping and Decay of Messenger RNA Occur in Cytoplasmic Processing Bodies , 2003 .
[61] Richard J Jackson,et al. MicroRNAs repress translation of m7Gppp-capped target mRNAs in vitro by inhibiting initiation and promoting deadenylation. , 2007, Genes & development.
[62] Yudong D. He,et al. Effects of atmospheric ozone on microarray data quality. , 2003, Analytical chemistry.
[63] Yvonne Tay,et al. MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation , 2008, Nature.
[64] J. Steitz,et al. Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5′ UTR as in the 3′ UTR , 2007, Proceedings of the National Academy of Sciences.
[65] Yang Yu,et al. Evidence that microRNAs are associated with translating messenger RNAs in human cells , 2006, Nature Structural &Molecular Biology.
[66] R. Hegde,et al. The concept of translocational regulation , 2008, The Journal of cell biology.
[67] Gregory J. Hannon,et al. MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies , 2005, Nature Cell Biology.
[68] Joel D. Richter,et al. Cytoplasmic Polyadenylation in Development and Beyond , 1999, Microbiology and Molecular Biology Reviews.
[69] J. Yates,et al. A role for the P-body component GW182 in microRNA function , 2005, Nature Cell Biology.
[70] M. Gorospe,et al. Global mRNA Stabilization Preferentially Linked to Translational Repression during the Endoplasmic Reticulum Stress Response , 2004, Molecular and Cellular Biology.
[71] W. Filipowicz,et al. Relief of microRNA-Mediated Translational Repression in Human Cells Subjected to Stress , 2006, Cell.
[72] Gavin Sherlock,et al. The Stanford Microarray Database: implementation of new analysis tools and open source release of software , 2002, Nucleic Acids Res..
[73] V. Kruys,et al. Identification of a translation inhibitory element (TIE) in the 3' untranslated region of the human interferon-beta mRNA. , 1988, Gene.
[74] Daniel Herschlag,et al. Dissecting eukaryotic translation and its control by ribosome density mapping , 2005, Nucleic acids research.
[75] D. Botstein,et al. Cluster analysis and display of genome-wide expression patterns. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[76] J. Belasco,et al. Importance of Translation and Nonnucleolytic Ago Proteins for On-Target RNA Interference , 2008, Current Biology.
[77] H. Grosshans,et al. Repression of C. elegans microRNA targets at the initiation level of translation requires GW182 proteins , 2009, The EMBO journal.
[78] B. Reinhart,et al. The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans , 2000, Nature.
[79] John D. Storey,et al. Genome-wide analysis of mRNA translation profiles in Saccharomyces cerevisiae , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[80] W. Filipowicz,et al. Inhibition of Translational Initiation by Let-7 MicroRNA in Human Cells , 2005, Science.
[81] E. Karsenti,et al. Fertilization of Xenopus eggs imposes a complete translational arrest of mRNAs containing 3'UUAUUUAU elements , 1994, FEBS letters.
[82] V. Ambros,et al. The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation. , 1999, Developmental biology.
[83] C. Novina,et al. MicroRNA-repressed mRNAs contain 40S but not 60S components , 2008, Proceedings of the National Academy of Sciences.
[84] C. Burge,et al. The Widespread Impact of Mammalian MicroRNAs on mRNA Repression and Evolution , 2005, Science.
[85] Shigeyuki Yokoyama,et al. Let-7 microRNA-mediated mRNA deadenylation and translational repression in a mammalian cell-free system. , 2007, Genes & development.
[86] G. Ruvkun,et al. Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans , 1993, Cell.
[87] W. J. Lucas,et al. Visualizing mRNA expression in plant protoplasts: factors influencing efficient mRNA uptake and translation. , 1989, The Plant cell.
[88] Joshua J. Forman,et al. A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence , 2008, Proceedings of the National Academy of Sciences.
[89] R. Plasterk,et al. The diverse functions of microRNAs in animal development and disease. , 2006, Developmental cell.
[90] Ligang Wu,et al. MicroRNAs direct rapid deadenylation of mRNA. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[91] S. Holm. A Simple Sequentially Rejective Multiple Test Procedure , 1979 .
[92] Ligang Wu,et al. Micro-RNA Regulation of the Mammalian lin-28 Gene during Neuronal Differentiation of Embryonal Carcinoma Cells , 2005, Molecular and Cellular Biology.
[93] David P. Bartel,et al. Early origins and evolution of microRNAs and Piwi-interacting RNAs in animals , 2008, Nature.
[94] G. Galili,et al. Translational regulation of human beta interferon mRNA: association of the 3' AU-rich sequence with the poly(A) tail reduces translation efficiency in vitro , 1993 .
[95] Yili Yang,et al. Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli. , 2000, Science.
[96] W. Filipowicz,et al. Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? , 2008, Nature Reviews Genetics.
[97] N. Rajewsky,et al. Widespread changes in protein synthesis induced by microRNAs , 2008, Nature.
[98] V. Ambros. The functions of animal microRNAs , 2004, Nature.
[99] John G Doench,et al. Recapitulation of short RNA-directed translational gene silencing in vitro. , 2006, Molecular cell.
[100] H. Horvitz,et al. MicroRNA expression profiles classify human cancers , 2005, Nature.
[101] C. Burge,et al. Prediction of Mammalian MicroRNA Targets , 2003, Cell.
[102] Alok J. Saldanha,et al. Java Treeview - extensible visualization of microarray data , 2004, Bioinform..
[103] Phillip A Sharp,et al. siRNAs can function as miRNAs , 2003 .
[104] L. Lim,et al. MicroRNA targeting specificity in mammals: determinants beyond seed pairing. , 2007, Molecular cell.
[105] John G Doench,et al. Specificity of microRNA target selection in translational repression. , 2004, Genes & development.
[106] H. Horvitz,et al. The let-7 MicroRNA family members mir-48, mir-84, and mir-241 function together to regulate developmental timing in Caenorhabditis elegans. , 2005, Developmental cell.
[107] Mihaela Zavolan,et al. Effects of Dicer and Argonaute down-regulation on mRNA levels in human HEK293 cells , 2006, Nucleic acids research.
[108] A. Pasquinelli,et al. Regulation by let-7 and lin-4 miRNAs Results in Target mRNA Degradation , 2005, Cell.
[109] Jerry Pelletier,et al. Short RNAs repress translation after initiation in mammalian cells. , 2006, Molecular cell.
[110] Isabelle Behm-Ansmant,et al. A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing. , 2005, RNA.
[111] Ligang Wu,et al. Let me count the ways: mechanisms of gene regulation by miRNAs and siRNAs. , 2008, Molecular cell.
[112] D. Bartel,et al. The impact of microRNAs on protein output , 2008, Nature.
[113] J. Armstrong,et al. The effect of capping and polyadenylation on the stability, movement and translation of synthetic messenger RNAs in Xenopus oocytes. , 1985, Nucleic acids research.
[114] B. Cullen,et al. MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[115] Yi Wen Kong,et al. The mechanism of micro-RNA-mediated translation repression is determined by the promoter of the target gene , 2008, Proceedings of the National Academy of Sciences.
[116] L. Lim,et al. Transcripts Targeted by the MicroRNA-16 Family Cooperatively Regulate Cell Cycle Progression , 2007, Molecular and Cellular Biology.
[117] A. van Hoof,et al. Messenger RNA regulation: to translate or to degrade , 2008, The EMBO journal.
[118] B. Chatterjee,et al. Translation and stability of rat liver messenger RNA for alpha 2 mu-globulin in Xenopus oocyte. The role of terminal poly(A). , 1979, The Journal of biological chemistry.
[119] J. Richter,et al. Human let-7a miRNA blocks protein production on actively translating polyribosomes , 2006, Nature Structural &Molecular Biology.
[120] George Easow,et al. Isolation of microRNA targets by miRNP immunopurification. , 2007, RNA.
[121] Elisa Izaurralde,et al. Deadenylation is a widespread effect of miRNA regulation. , 2008, RNA.