Reverse engineering the genotype–phenotype map with natural genetic variation
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[1] Yan Cui,et al. Inferring gene transcriptional modulatory relations: a genetical genomics approach. , 2005, Human molecular genetics.
[2] Rachel B. Brem,et al. Integrating large-scale functional genomic data to dissect the complexity of yeast regulatory networks , 2008, Nature Genetics.
[3] Alberto de la Fuente,et al. Discovery of meaningful associations in genomic data using partial correlation coefficients , 2004, Bioinform..
[4] Olga G. Troyanskaya,et al. Nearest Neighbor Networks: clustering expression data based on gene neighborhoods , 2007, BMC Bioinformatics.
[5] Elias Chaibub Neto,et al. Genetic Networks of Liver Metabolism Revealed by Integration of Metabolic and Transcriptional Profiling , 2008, PLoS genetics.
[6] Rory A. Fisher,et al. The Arrangement of Field Experiments , 1992 .
[7] G. Churchill,et al. Evidence of a Large-Scale Functional Organization of Mammalian Chromosomes , 2005, PLoS biology.
[8] Nengjun Yi,et al. The Collaborative Cross, a community resource for the genetic analysis of complex traits , 2004, Nature Genetics.
[9] L. Kruglyak,et al. Genetics of global gene expression , 2006, Nature Reviews Genetics.
[10] John D. Storey,et al. Mapping the Genetic Architecture of Gene Expression in Human Liver , 2008, PLoS biology.
[11] E. Schadt,et al. Genetic and Genomic Analysis of a Fat Mass Trait with Complex Inheritance Reveals Marked Sex Specificity , 2006, PLoS genetics.
[12] T. Ohta. Origin of the neutral and nearly neutral theories of evolution , 2003, Journal of Biosciences.
[13] Yonina C. Eldar,et al. eQED: an efficient method for interpreting eQTL associations using protein networks , 2008, Molecular systems biology.
[14] L. Kruglyak,et al. Genetic Dissection of Transcriptional Regulation in Budding Yeast , 2002, Science.
[15] Ritsert C. Jansen,et al. Studying complex biological systems using multifactorial perturbation , 2003, Nature Reviews Genetics.
[16] N. Bing,et al. Genetical Genomics Analysis of a Yeast Segregant Population for Transcription Network Inference , 2005, Genetics.
[17] J. Akey,et al. The Evolution of Gene Expression QTL in Saccharomyces cerevisiae , 2007, PloS one.
[18] J. Zhu,et al. An integrative genomics approach to the reconstruction of gene networks in segregating populations , 2004, Cytogenetic and Genome Research.
[19] L. Almasy,et al. Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes , 2007, Nature Genetics.
[20] Gary A. Churchill,et al. The Genetics of Gene Expression , 2006, Mammalian Genome.
[21] Robert W. Williams,et al. Methodological aspects of the genetic dissection of gene expression , 2005, Bioinform..
[22] Rachel B. Brem,et al. Trans-acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors , 2003, Nature Genetics.
[23] G. Churchill,et al. Applying Gene Expression, Proteomics and Single-Nucleotide Polymorphism Analysis for Complex Trait Gene Identification , 2008, Genetics.
[24] N. Barton,et al. Multifactorial genetics: Understanding quantitative genetic variation , 2002, Nature Reviews Genetics.
[25] S. Horvath,et al. Variations in DNA elucidate molecular networks that cause disease , 2008, Nature.
[26] S. Horvath,et al. Evidence for anti-Burkitt tumour globulins in Burkitt tumour patients and healthy individuals. , 1967, British Journal of Cancer.
[27] E. Plahte,et al. Gene regulatory networks generating the phenomena of additivity, dominance and epistasis. , 2000, Genetics.
[28] Stig W Omholt,et al. Statistical Epistasis Is a Generic Feature of Gene Regulatory Networks , 2007, Genetics.
[29] R. Doerge,et al. Global eQTL Mapping Reveals the Complex Genetic Architecture of Transcript-Level Variation in Arabidopsis , 2007, Genetics.
[30] A. G. de la Fuente,et al. Gene Network Inference via Structural Equation Modeling in Genetical Genomics Experiments , 2008, Genetics.
[31] J. Stamatoyannopoulos,et al. The genomics of gene expression. , 2004, Genomics.
[32] H. Stefánsson,et al. Genetics of gene expression and its effect on disease , 2008, Nature.
[33] C. Molony,et al. Genetic analysis of genome-wide variation in human gene expression , 2004, Nature.
[34] Amy K. Schmid,et al. A Predictive Model for Transcriptional Control of Physiology in a Free Living Cell , 2007, Cell.
[35] J. Lamb,et al. Elucidating the murine brain transcriptional network in a segregating mouse population to identify core functional modules for obesity and diabetes , 2006, Journal of neurochemistry.
[36] Eric E Schadt,et al. Cis-acting expression quantitative trait loci in mice. , 2005, Genome research.
[37] J. Castle,et al. An integrative genomics approach to infer causal associations between gene expression and disease , 2005, Nature Genetics.
[38] Rachel B. Brem,et al. The landscape of genetic complexity across 5,700 gene expression traits in yeast. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[39] Keith Shockley,et al. Structural Model Analysis of Multiple Quantitative Traits , 2006, PLoS genetics.
[40] Paul M. Magwene,et al. Estimating genomic coexpression networks using first-order conditional independence , 2004, Genome Biology.
[41] J. Nap,et al. Genetical genomics : the added value from segregation , 2001 .
[42] Susan Oyama. The Ontogeny of Information: Developmental Systems and Evolution , 2000 .
[43] David R Goodlett,et al. Genetic basis of proteome variation in yeast , 2007, Nature Genetics.
[44] John D. Storey,et al. Multiple Locus Linkage Analysis of Genomewide Expression in Yeast , 2005, PLoS biology.
[45] Jingyuan Fu,et al. Mapping Determinants of Gene Expression Plasticity by Genetical Genomics in C. elegans , 2006, PLoS genetics.
[46] Andrew I Su,et al. Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics' , 2005, Nature Genetics.
[47] D. Nott,et al. Genetic dissection of gene regulation in multiple mouse tissues , 2006, Mammalian Genome.
[48] L. Kruglyak,et al. Gene–Environment Interaction in Yeast Gene Expression , 2008, PLoS biology.
[49] Michal Linial,et al. Using Bayesian Networks to Analyze Expression Data , 2000, J. Comput. Biol..
[50] C. Kendziorski,et al. Statistical Methods for Expression Quantitative Trait Loci (eQTL) Mapping , 2006, Biometrics.
[51] Eric E. Schadt,et al. Moving toward a system genetics view of disease , 2007, Mammalian Genome.
[52] Rudi Alberts,et al. A Statistical Multiprobe Model for Analyzing cis and trans Genes in Genetical Genomics Experiments With Short-Oligonucleotide Arrays , 2005, Genetics.
[53] John D. Storey,et al. Harnessing naturally randomized transcription to infer regulatory relationships among genes , 2007, Genome Biology.
[54] Jun Zhu,et al. Increasing the Power to Detect Causal Associations by Combining Genotypic and Expression Data in Segregating Populations , 2007, PLoS Comput. Biol..
[55] M. Lynch,et al. Genetics and Analysis of Quantitative Traits , 1996 .
[56] David Kulp,et al. Causal Inference of Regulator-Target Pairs by Gene Mapping of Expression Phenotypes , 2005, Systems Biology and Regulatory Genomics.
[57] M. McCarthy,et al. Genome-wide association studies for complex traits: consensus, uncertainty and challenges , 2008, Nature Reviews Genetics.
[58] R. Stoughton,et al. Genetics of gene expression surveyed in maize, mouse and man , 2003, Nature.
[59] Leonid Kruglyak,et al. Local Regulatory Variation in Saccharomyces cerevisiae , 2005, PLoS genetics.
[60] M. Pérez-Enciso. In Silico Study of Transcriptome Genetic Variation in Outbred Populations , 2004, Genetics.
[61] John D. Storey,et al. Genetic interactions between polymorphisms that affect gene expression in yeast , 2005, Nature.
[62] Li Wang,et al. An integrative approach for causal gene identification and gene regulatory pathway inference , 2006, ISMB.
[63] E. Petretto,et al. Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease , 2005, Nature Genetics.
[64] L. Liang,et al. A genome-wide association study of global gene expression , 2007, Nature Genetics.
[65] D. Pe’er,et al. Identifying regulatory mechanisms using individual variation reveals key role for chromatin modification , 2006, Proceedings of the National Academy of Sciences.
[66] Shizhong Xu,et al. Mapping Quantitative Trait Loci for Expression Abundance , 2007, Genetics.
[67] C. Aquadro,et al. Levels of naturally occurring DNA polymorphism correlate with recombination rates in D. melanogaster , 1992, Nature.
[68] R. A. Fisher,et al. The Genetical Theory of Natural Selection , 1931 .
[69] Daniel J. Kliebenstein,et al. Linking Metabolic QTLs with Network and cis-eQTLs Controlling Biosynthetic Pathways , 2007, PLoS genetics.
[70] Paul Schliekelman,et al. Statistical Power of Expression Quantitative Trait Loci for Mapping of Complex Trait Loci in Natural Populations , 2008, Genetics.
[71] B. Charlesworth,et al. The effect of deleterious mutations on neutral molecular variation. , 1993, Genetics.
[72] A. Clark,et al. Regulatory changes underlying expression differences within and between Drosophila species , 2008, Nature Genetics.
[73] R. Kulathinal,et al. Fine-scale mapping of recombination rate in Drosophila refines its correlation to diversity and divergence , 2008, Proceedings of the National Academy of Sciences.