The immunodepressive effect of infectious bursal disease virus in chickens.

SUMMARY Infectious bursal disease virus (IBVD) depressed the humoral antibody response of chickens to various vaccines. The virus had that effect whether injected at the same time as vaccination or 4 or 7 days before. The depression was slightly greater when injection was 7 days before, and was most pronounced in chickens inoculated with IBDV when 6 weeks old, slight in 4-week-olds, and absent in 2-week-olds. Protection against challenge by virulent ND virus 3 weeks after ND vaccination showed the marked differences between IBDV-inoculated and uninoculated chickens.

[1]  義孝 鈴木,et al.  Infectious bursal disease virus (IBDV)の分離とわが国におけるIBDV沈降抗体の分布について , 1973 .

[2]  K. Hirai,et al.  Immunodiffusion reaction to avian infectious bursal virus. , 1972, Avian diseases.

[3]  W. H. Allan,et al.  Immunosuppressive effect of the infectious bursal agent in the chicken. , 1972, Nature: New biology.

[4]  W. H. Allan,et al.  Immunosuppression by the infectious bursal agent in chickens immunised against Newcastle disease , 1972, Veterinary Record.

[5]  C. Morris,et al.  Depression of thymus-and bursa-dependent immune systems chicks with Marek's disease. , 1971, Avian diseases.

[6]  M. Kripke,et al.  Immunologic deficiency associated with mammary tumor virus (MTV) infection in mice: hemagglutinin response and allograft survival. , 1971, Journal of immunology.

[7]  B. R. Cho.  Experimental dual infections of chickens with infectious bursal and Marek's disease agents. I. Preliminary observation on the effect of infectious bursal agent on Marek's disease. , 1970, Avian diseases.

[8]  R. Gatti,et al.  The lymphoid system. , 1970, Annual review of physiology.

[9]  M. Salaman.  Immunodepression by viruses. , 1969, Antibiotica et chemotherapia. Fortschritte. Advances. Progres.

[10]  C. Mims,et al.  The immunodepressive action of lymphocytic choriomeningitis virus in mice. , 1968, Journal of immunology.

[11]  J. Osborn,et al.  Immunosuppression during acute murine cytomegalovirus infection. , 1968, Journal of immunology.

[12]  P. Biggs,et al.  Effect of lymphoid leukosis and Marek's disease on the immunological responsiveness of the chicken. , 1968, Journal of the National Cancer Institute.

[13]  Cheville Nf.  Studies on the pathogenesis of Gumboro disease in the bursa of Fabricius, spleen, and thymus of the chicken. , 1967 .

[14]  J. Osborn,et al.  Suppression of Interferon and Antibody and Multiplication of Newcastle Disease Virus in Gytomegalovirus Infected Mice.∗ , 1967, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[15]  Warner Nl.  The immunological role of the avian thymus and bursa of fabricius. , 1967 .

[16]  M. Weissenbacher,et al.  Inhibition of immune response in experimental hemorrhagic fever (Junin virus). , 1967 .

[17]  M. Cooper,et al.  Role of the thymus and other central lymphoid tissues in immunological disease. , 1967, Annual review of medicine.

[18]  T. Odaka,et al.  Inhibitory effect of Friend leukemia virus infection on the antibody formation to sheep erythrocytes in mice. , 1966, The Japanese journal of experimental medicine.

[19]  B. Siegel,et al.  Depressed antibody response in the mouse infected with Rauscher leukaemia virus. , 1966, Immunology.

[20]  N. Wedderburn,et al.  The immunodepressive effect of friend virus. , 1966 .

[21]  M. Cooper,et al.  THE FUNCTIONS OF THE THYMUS SYSTEM AND THE BURSA SYSTEM IN THE CHICKEN , 1966, The Journal of experimental medicine.

[22]  C. Helmboldt,et al.  Experimentally Induced Gumboro Disease (IBA) , 1964 .

[23]  Winterfield Rw,et al.  Etiology of an infectious nephritis-nephrosis syndrome of chickens. , 1962 .

[24]  A. Cosgrove.  An Apparently New Disease of Chickens: Avian Nephrosis , 1962 .

[25]  A. R. Winter,et al.  The Significance of the Bursa of Fabricius in Antibody Production in Chickens 1. Age of Chickens , 1957 .

[26]  B. Glick,et al.  The Bursa of Fabricius and Antibody Production , 1956 .

[27]  Hitchner Sb,et al.  A virus of low virulence for immunizing fowls against Newcastle disease; avian pneumoencephalitis. , 1948 .