Sinusoidal Stimulation of Myocardial Tissue:

Sinusoidal Stimulation of Cardiac Cells. Introduction: Cardiac tissue subjected to sinasoidal stimulus Is characterized by action potentials (APs) that have extended plateau phases, sustained for the duration of the stimulus. Extended action potential durations (APDs) are beneficial because they disrupt wandering wavelets in the fibrillating heart. To investigate the mechanisms by which periodic stimulus affects cardiac tissue, particularly the development of sustained depolarization, computer simulations of single cardiac cells exposed to alternating current (AC) are performed.

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