Addressing PXR liabilities of phthalazine-based hedgehog/smoothened antagonists using novel pyridopyridazines.
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R. Hungate | M. Rong | W. Zhong | Michael G. Johnson | Gary Lee | Q. Ye | D. McMinn | Guifen Xu | Matthew F Brown | M. Toteva | Jacob A. Kaizerman | Jessica Orf | D. Wickramasinghe | Tom Huang | J. Kaizerman | W. Aaron | Songzhu An | R. Austin | Angela Chong | Ben Jiang | Brian S. Lucas | M. Johnson | Michael G. Johnson