Crystal structure of the human sterol transporter ABCG5/ABCG8

[1]  F. Theodoulou,et al.  ABC transporter research: going strong 40 years on , 2015, Biochemical Society transactions.

[2]  David E. Kim,et al.  Large-scale determination of previously unsolved protein structures using evolutionary information , 2015, eLife.

[3]  D. Y. Lin,et al.  Crystal structures of a polypeptide processing and secretion transporter , 2015, Nature.

[4]  Jonathan C. Cohen,et al.  Relative roles of ABCG5/ABCG8 in liver and intestine , 2015, Journal of Lipid Research.

[5]  G. Murshudov,et al.  Conformation-independent structural comparison of macromolecules with ProSMART , 2014, Acta crystallographica. Section D, Biological crystallography.

[6]  D. Baker,et al.  Robust and accurate prediction of residue–residue interactions across protein interfaces using evolutionary information , 2014, eLife.

[7]  Benjamin D. Madej,et al.  Lipid14: The Amber Lipid Force Field , 2014, Journal of chemical theory and computation.

[8]  Kazutaka Katoh,et al.  MAFFT: iterative refinement and additional methods. , 2014, Methods in molecular biology.

[9]  Nick V Grishin,et al.  PROMALS3D: multiple protein sequence alignment enhanced with evolutionary and three-dimensional structural information. , 2014, Methods in molecular biology.

[10]  Faqi Wang,et al.  Characterization of the Role of a Highly Conserved Sequence in ATP Binding Cassette Transporter G (ABCG) Family in ABCG1 Stability, Oligomerization, and Trafficking , 2013, Biochemistry.

[11]  D. Baker,et al.  Assessing the utility of coevolution-based residue–residue contact predictions in a sequence- and structure-rich era , 2013, Proceedings of the National Academy of Sciences.

[12]  E. Pardon,et al.  Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain , 2013, Proceedings of the National Academy of Sciences.

[13]  Shanshuang Chen,et al.  Carbon catabolite repression of the maltose transporter revealed by X-ray crystallography , 2013, Nature.

[14]  Z. Dauter,et al.  Identification of patterns in diffraction intensities affected by radiation exposure. , 2013, Journal of synchrotron radiation.

[15]  M. Hohl,et al.  Crystal structure of a heterodimeric ABC transporter in its inward-facing conformation , 2012, Nature Structural &Molecular Biology.

[16]  Jue Chen,et al.  Crystal Structure of the Maltose Transporter in a Pretranslocation Intermediate State , 2011, Science.

[17]  Michael Lappe,et al.  CMView: Interactive contact map visualization and analysis , 2011, Bioinform..

[18]  Randy J. Read,et al.  Overview of the CCP4 suite and current developments , 2011, Acta crystallographica. Section D, Biological crystallography.

[19]  Jonathan C. Cohen,et al.  Sequences in the Nonconsensus Nucleotide-binding Domain of ABCG5/ABCG8 Required for Sterol Transport* , 2011, The Journal of Biological Chemistry.

[20]  Brandy J. Johnson,et al.  Bile acids stimulate ATP hydrolysis in the purified cholesterol transporter ABCG5/G8. , 2010, Biochemistry.

[21]  Zbyszek Otwinowski,et al.  Diffraction data analysis in the presence of radiation damage , 2010, Acta crystallographica. Section D, Biological crystallography.

[22]  P. Emsley,et al.  Features and development of Coot , 2010, Acta crystallographica. Section D, Biological crystallography.

[23]  George M. Sheldrick,et al.  Experimental phasing with SHELXC/D/E: combining chain tracing with density modification , 2010, Acta crystallographica. Section D, Biological crystallography.

[24]  I. Bahar,et al.  Normal mode analysis of biomolecular structures: functional mechanisms of membrane proteins. , 2010, Chemical reviews.

[25]  Milton H. Saier,et al.  Membrane Porters of ATP-Binding Cassette Transport Systems Are Polyphyletic , 2009, Journal of Membrane Biology.

[26]  Lauren Wickstrom,et al.  Evaluating the performance of the ff99SB force field based on NMR scalar coupling data. , 2009, Biophysical journal.

[27]  M. Caffrey Crystallizing membrane proteins for structure determination: use of lipidic mesophases. , 2009, Annual review of biophysics.

[28]  Narayanan Eswar,et al.  Protein structure modeling with MODELLER. , 2008, Methods in molecular biology.

[29]  R. Stevens,et al.  GPCR Engineering Yields High-Resolution Structural Insights into β2-Adrenergic Receptor Function , 2007, Science.

[30]  K. Locher,et al.  Asymmetry in the Structure of the ABC Transporter-Binding Protein Complex BtuCD-BtuF , 2007, Science.

[31]  R. Dawson,et al.  Structure and mechanism of ABC transporter proteins. , 2007, Current opinion in structural biology.

[32]  Yenphuong T. Trinh,et al.  Expression of 25 human ABC transporters in the yeast Pichia pastoris and characterization of the purified ABCC3 ATPase activity. , 2007, Biochemistry.

[33]  Jack Snoeyink,et al.  Nucleic Acids Research Advance Access published April 22, 2007 MolProbity: all-atom contacts and structure validation for proteins and nucleic acids , 2007 .

[34]  K. Locher,et al.  Structure of an ABC transporter in complex with its binding protein , 2007, Nature.

[35]  Ian T. Paulsen,et al.  TransportDB: a comprehensive database resource for cytoplasmic membrane transport systems and outer membrane channels , 2006, Nucleic Acids Res..

[36]  Zbyszek Otwinowski,et al.  The many faces of radiation-induced changes. , 2007, Journal of synchrotron radiation.

[37]  P. Kollman,et al.  Automatic atom type and bond type perception in molecular mechanical calculations. , 2006, Journal of molecular graphics & modelling.

[38]  Kevin Cowtan,et al.  The Buccaneer software for automated model building. 1. Tracing protein chains. , 2006, Acta crystallographica. Section D, Biological crystallography.

[39]  Wladek Minor,et al.  HKL-3000: the integration of data reduction and structure solution--from diffraction images to an initial model in minutes. , 2006, Acta crystallographica. Section D, Biological crystallography.

[40]  Lynne A. Goodwin,et al.  Pathogenomic Sequence Analysis of Bacillus cereus and Bacillus thuringiensis Isolates Closely Related to Bacillus anthracis , 2006, Journal of bacteriology.

[41]  Jonathan C. Cohen,et al.  Functional Asymmetry of Nucleotide-binding Domains in ABCG5 and ABCG8* , 2006, Journal of Biological Chemistry.

[42]  Holger Gohlke,et al.  The Amber biomolecular simulation programs , 2005, J. Comput. Chem..

[43]  J. Bowie,et al.  Crystallization of bacteriorhodopsin from bicelle formulations at room temperature , 2005, Protein science : a publication of the Protein Society.

[44]  Lars Malmström,et al.  Prediction of CASP6 structures using automated robetta protocols , 2005, Proteins.

[45]  Andrei N. Lupas,et al.  CLANS: a Java application for visualizing protein families based on pairwise similarity , 2004, Bioinform..

[46]  Marian Anghel,et al.  Synchronization of trajectories in canonical molecular-dynamics simulations: observation, explanation, and exploitation. , 2004, The Journal of chemical physics.

[47]  I. Bataronov,et al.  Processing of X-Ray Diffraction Data in Structure Investigations of Amorphous Metal Oxides , 2004 .

[48]  Celeste Sagui,et al.  Towards an accurate representation of electrostatics in classical force fields: efficient implementation of multipolar interactions in biomolecular simulations. , 2004, The Journal of chemical physics.

[49]  Jonathan C. Cohen,et al.  ABCG5 and ABCG8 Are Obligate Heterodimers for Protein Trafficking and Biliary Cholesterol Excretion* , 2003, Journal of Biological Chemistry.

[50]  Wladek Minor,et al.  Measurement errors and their consequences in protein crystallography. , 2003, Acta crystallographica. Section D, Biological crystallography.

[51]  Z. Otwinowski,et al.  research papers Acta Crystallographica Section A Foundations of , 2003 .

[52]  Jonathan C. Cohen,et al.  Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[53]  Runying Tian,et al.  Genome sequence of Streptococcus mutans UA159, a cariogenic dental pathogen , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[54]  Jonathan C. Cohen,et al.  Coexpression of ATP-binding cassette proteins ABCG5 and ABCG8 permits their transport to the apical surface , 2002 .

[55]  A. Pandya,et al.  Two genes that map to the STSL locus cause sitosterolemia: genomic structure and spectrum of mutations involving sterolin-1 and sterolin-2, encoded by ABCG5 and ABCG8, respectively. , 2001, American journal of human genetics.

[56]  Jimin Pei,et al.  AL2CO: calculation of positional conservation in a protein sequence alignment , 2001, Bioinform..

[57]  A. Rzhetsky,et al.  The human ATP-binding cassette (ABC) transporter superfamily. , 2001, Genome research.

[58]  Anand K. Srivastava,et al.  Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption , 2001, Nature Genetics.

[59]  N. Grishin,et al.  Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters. , 2000, Science.

[60]  G. Cox,et al.  Mutations in the white gene of Drosophila melanogaster affecting ABC transporters that determine eye colouration. , 1999, Biochimica et biophysica acta.

[61]  K Cowtan,et al.  Miscellaneous algorithms for density modification. , 1998, Acta crystallographica. Section D, Biological crystallography.

[62]  B. Goldman,et al.  Transmembrane heme delivery systems. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[63]  G. Murshudov,et al.  Refinement of macromolecular structures by the maximum-likelihood method. , 1997, Acta crystallographica. Section D, Biological crystallography.

[64]  Z. Otwinowski,et al.  [20] Processing of X-ray diffraction data collected in oscillation mode. , 1997, Methods in enzymology.

[65]  K Cowtan,et al.  Combining constraints for electron-density modification. , 1997, Methods in enzymology.

[66]  D. Karamata,et al.  The tagGH operon of Bacillus subtilis 168 encodes a two‐component ABC transporter involved in the metabolism of two wall teichoic acids , 1995, Molecular microbiology.

[67]  G. Cox,et al.  Mutational analysis of the traffic ATPase (ABC) transporters involved in uptake of eye pigment precursors in Drosophila melanogaster. Implications for structure-function relationships. , 1994, The Journal of biological chemistry.

[68]  P. Kollman,et al.  A well-behaved electrostatic potential-based method using charge restraints for deriving atomic char , 1993 .

[69]  I. J. Evans,et al.  The nodI gene product of Rhizobium leguminosarum is closely related to ATP-binding bacterial transport proteins; nucleotide sequence analysis of the nodI and nodJ genes. , 1986, Gene.

[70]  X. Xie,et al.  Inhibition of clathrin-coated vesicle acidification by duramycin. , 1984, The Journal of biological chemistry.

[71]  W. L. Jorgensen,et al.  Comparison of simple potential functions for simulating liquid water , 1983 .

[72]  G. Ciccotti,et al.  Numerical Integration of the Cartesian Equations of Motion of a System with Constraints: Molecular Dynamics of n-Alkanes , 1977 .

[73]  Thomas Hunt Morgan,et al.  Sex-linked inheritance in Drosophila , 1916 .