A Real-Time Medical Ultrasound Simulator Based on a Generative Adversarial Network Model

This paper presents an artificial intelligence-based ultrasound simulator suitable for medical simulation and clinical training. Particularly, we propose a machine learning approach to realistically simulate ultrasound images based on generative adversarial networks (GANs). Using B-mode ultrasound images simulated by a known ultrasound simulator, Field II, an "image-to-image" ultrasound simulator was trained. Then, through evaluations, we found that the GAN-based simulator can generate B-mode images following Rayleigh scattering. Our preliminary study demonstrated that ultrasound B-mode images from anatomies inferred from magnetic resonance imaging (MRI) data were feasible. While some image blurring was observed, ultrasound B- mode images obtained were both visually and quantitatively comparable to those obtained using the Field II simulator. It is also important to note that the GAN-based ultrasound simulator was computationally efficient and could achieve a frame rate of 15 frames/second using a regular laptop computer. In the future, the proposed GAN-based simulator will be used to synthesize more realistic looking ultrasound images with artifacts such as shadowing.