Genome-wide association analysis identifies new candidate risk loci for familial intracranial aneurysm in the French-Canadian population

[1]  Jianguo Huang,et al.  The Emerging Role of Cables1 in Cancer and Other Diseases , 2017, Molecular Pharmacology.

[2]  Jingjin Liu,et al.  Cables1 Inhibits Proliferation and Induces Senescence by Angiotensin II via a p21-Dependent Pathway in Human Umbilical Vein Endothelial Cells , 2017, Journal of Vascular Research.

[3]  C. Chung,et al.  Enhanced Innate Inflammation Induced by Anti-BTLA Antibody in Dual Insult Model of Hemorrhagic Shock/Sepsis , 2016, Shock.

[4]  P. Visscher,et al.  Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index , 2015, Nature Genetics.

[5]  S. Shirasawa,et al.  Upregulation of ATG3 contributes to autophagy induced by the detachment of intestinal epithelial cells from the extracellular matrix, but promotes autophagy-independent apoptosis of the attached cells , 2015, Autophagy.

[6]  Daniel L. Koller,et al.  Genome-Wide Association Study of Intracranial Aneurysm Identifies a New Association on Chromosome 7 , 2014 .

[7]  Carson C Chow,et al.  Second-generation PLINK: rising to the challenge of larger and richer datasets , 2014, GigaScience.

[8]  Andrew D. Johnson,et al.  Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia. , 2014, American journal of human genetics.

[9]  T. Graham,et al.  Impairment of autophagy in endothelial cells prevents shear-stress-induced increases in nitric oxide bioavailability. , 2014, Canadian journal of physiology and pharmacology.

[10]  K. Huebner,et al.  Replicative Stress and the FHIT Gene: Roles in Tumor Suppression, Genome Stability and Prevention of Carcinogenesis , 2014, Cancers.

[11]  S. Kitsiou‐Tzeli,et al.  Microduplication 3q13.2q13.31 identified in a male with dysmorphic features and multiple congenital anomalies , 2014, American journal of medical genetics. Part A.

[12]  T. Lehtimäki,et al.  High Risk Population Isolate Reveals Low Frequency Variants Predisposing to Intracranial Aneurysms , 2014, PLoS genetics.

[13]  C. Ware,et al.  BTLA Interaction with HVEM Expressed on CD8+ T Cells Promotes Survival and Memory Generation in Response to a Bacterial Infection , 2013, PloS one.

[14]  M. Mendelsohn,et al.  Steroid-sensitive Gene 1 Is a Novel Cyclic GMP-dependent Protein Kinase I Substrate in Vascular Smooth Muscle Cells* , 2013, The Journal of Biological Chemistry.

[15]  Lisa J. Martin,et al.  Rank-based genome-wide analysis reveals the association of Ryanodine receptor-2 gene variants with childhood asthma among human populations , 2013, Human Genomics.

[16]  W. Koch,et al.  The role of oxidative stress in cerebral aneurysm formation and rupture. , 2013, Current neurovascular research.

[17]  G. Chiappetta,et al.  Tumor suppressor role of the CL2/DRO1/CCDC80 gene in thyroid carcinogenesis. , 2013, The Journal of clinical endocrinology and metabolism.

[18]  K. Sekiguchi,et al.  Equarin is involved in cell adhesion by means of heparan sulfate proteoglycan during lens development , 2013, Developmental dynamics : an official publication of the American Association of Anatomists.

[19]  Daniel L. Koller,et al.  Genome-Wide Association Study of Intracranial Aneurysms Confirms Role of Anril and SOX17 in Disease Risk , 2012, Stroke.

[20]  L. Gunhaga,et al.  A balance of FGF and BMP signals regulates cell cycle exit and Equarin expression in lens cells , 2012, Molecular biology of the cell.

[21]  Steven A. Bailey,et al.  Loss of coiled-coil domain containing 80 negatively modulates glucose homeostasis in diet-induced obese mice. , 2012, Endocrinology.

[22]  Yusuke Nakamura,et al.  Genome-wide association study for intracranial aneurysm in the Japanese population identifies three candidate susceptible loci and a functional genetic variant at EDNRA. , 2012, Human molecular genetics.

[23]  D. Gaudet,et al.  Genetic mapping of habitual substance use, obesity-related traits, responses to mental and physical stress, and heart rate and blood pressure measurements reveals shared genes that are overrepresented in the neural synapse , 2012, Hypertension Research.

[24]  Bo Peng,et al.  Integrated annotation and analysis of genetic variants from next-generation sequencing studies with variant tools , 2012, Bioinform..

[25]  O. Delaneau,et al.  A linear complexity phasing method for thousands of genomes , 2011, Nature Methods.

[26]  Xihong Lin,et al.  Rare-variant association testing for sequencing data with the sequence kernel association test. , 2011, American journal of human genetics.

[27]  P. Visscher,et al.  GCTA: a tool for genome-wide complex trait analysis. , 2011, American journal of human genetics.

[28]  Insuk Lee,et al.  Characterising and Predicting Haploinsufficiency in the Human Genome , 2010, PLoS genetics.

[29]  M. DePristo,et al.  The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data. , 2010, Genome research.

[30]  Michael Boehnke,et al.  LocusZoom: regional visualization of genome-wide association scan results , 2010, Bioinform..

[31]  Katsuhito Yasuno,et al.  Genome-wide association study to identify genetic variants present in Japanese patients harboring intracranial aneurysms , 2010, Journal of Human Genetics.

[32]  P. Visscher,et al.  Common SNPs explain a large proportion of heritability for human height , 2011 .

[33]  Alejandro F. Frangi,et al.  Genome-wide association study of intracranial aneurysm identifies three new risk loci , 2010, Nature genetics.

[34]  Murim Choi,et al.  Susceptibility loci for intracranial aneurysm in European and Japanese populations , 2008, Nature Genetics.

[35]  G. Rinkel,et al.  Natural history, epidemiology and screening of unruptured intracranial aneurysms. , 2008, Journal of neuroradiology. Journal de neuroradiologie.

[36]  A. Hofman,et al.  Incidental findings on brain MRI in the general population. , 2007, The New England journal of medicine.

[37]  P. Donnelly,et al.  A new multipoint method for genome-wide association studies by imputation of genotypes , 2007, Nature Genetics.

[38]  D. Reich,et al.  Principal components analysis corrects for stratification in genome-wide association studies , 2006, Nature Genetics.

[39]  A. Lanfranco,et al.  B and T Lymphocyte Attenuator-Mediated Signal Transduction Provides a Potent Inhibitory Signal to Primary Human CD4 T Cells That Can Be Initiated by Multiple Phosphotyrosine Motifs1 , 2006, The Journal of Immunology.

[40]  D. Nichols,et al.  Unruptured intracranial aneurysms: natural history, clinical outcome, and risks of surgical and endovascular treatment , 2003, The Lancet.

[41]  L. D. Barnes,et al.  Fhit, a putative tumor suppressor in humans, is a dinucleoside 5',5"'-P1,P3-triphosphate hydrolase. , 1996, Biochemistry.

[42]  L. Pérusse,et al.  Epidemiological Study of Ruptured Intracranial Aneurysms in the Saguenay-Lac-Saint-Jean region (Quebec, Canada) , 1996, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

[43]  F. Halal,et al.  Intracranial aneurysms: a report of a large pedigree. , 1983, American journal of medical genetics.

[44]  Shamil R Sunyaev,et al.  Pooled association tests for rare variants in exon-resequencing studies. , 2010, American journal of human genetics.

[45]  Xin Xu,et al.  Implementing a unified approach to family‐based tests of association , 2000, Genetic epidemiology.