Introduction to Fourier Transform Infrared Spectroscopy and Applications in the Pharmaceutical Sciences

The applications of infrared spectroscopy to pharmaceutical sciences is small compared to the applications of infrared spectroscopy to the fields of chemistry, biology, and biochemistry. This is unfortunate because modern routine infrared spectrometers are excellent research tools that provide very high signal-to-noise, high resolution, and extensive data-manipulation computer software packages. This review summarizes basic principles of infrared spectrometers and the use of Fourier self-deconvolution.

[1]  Gary Horlick,et al.  Introduction to Fourier Transform Spectroscopy , 1968 .

[2]  H. Mantsch,et al.  Polymorphic phase behaviour of phospholipid membranes studied by infrared spectroscopy. , 1984, Biochimica et biophysica acta.

[3]  H. Mantsch,et al.  High-pressure infrared spectroscopic evidence of water binding sites in 1,2-diacyl phospholipids , 1988 .

[4]  H. Mantsch,et al.  Fourier transform methods for spectral resolution enhancement , 1988 .

[5]  R. Guy,et al.  Percutaneous Penetration Enhancement in Vivo Measured by Attenuated Total Reflectance Infrared Spectroscopy , 1990, Pharmaceutical Research.

[6]  C. Pidgeon,et al.  Fourier transform infrared assay of liposomal lipids. , 1989, Analytical biochemistry.

[7]  Russell O. Potts,et al.  Macro- and molecular physical-chemical considerations in understanding drug transport in the stratum corneum , 1985 .

[8]  P. Griffiths.  Fourier Transform Infrared Spectrometry , 2007 .

[9]  H. Mantsch,et al.  New insight into protein secondary structure from resolution-enhanced infrared spectra. , 1988, Biochimica et biophysica acta.

[10]  W. F. Maddams,et al.  The Scope and Limitations of Curve Fitting , 1980 .

[11]  J S Hyde,et al.  Microimmiscibility and three-dimensional dynamic structures of phosphatidylcholine-cholesterol membranes: translational diffusion of a copper complex in the membrane. , 1990, Biochemistry.

[12]  Forensic Science Applications of Diffuse Reflectance Infrared Fourier Transform Spectroscopy (DRIFTS): II. Direct Analysis of Some Tablets, Capsule Powders, and Powders , 1986 .

[13]  Douglas J. Moffatt,et al.  Fourier Self-Deconvolution: A Method for Resolving Intrinsically Overlapped Bands , 1981 .

[14]  R. Jones,et al.  The control ot errors in infrared spectrophotometry—I the reduction of finite slit distortion by the method of ``pseudo-deconvolution'' , 1967 .

[15]  H. Susi,et al.  Examination of the secondary structure of proteins by deconvolved FTIR spectra , 1986, Biopolymers.

[16]  C. Pidgeon,et al.  Formation of the antiplanar-antiplanar phosphate conformation of dilauroylphosphatidylcholine bilayers. , 1990, Biochimica et biophysica acta.

[17]  J. Koenig,et al.  Objective Criteria for Absorbance Subtraction , 1984 .

[18]  P. Griffiths,et al.  Introduction to spectral deconvolution , 1986 .

[19]  H. Mantsch,et al.  Fourier transforms in the computation of self-deconvoluted and first-order derivative spectra of overlapped band contours , 1981 .

[20]  C. Pidgeon,et al.  Fourier transform infrared assay of membrane lipids immobilized to silica: leaching and stability of immobilized artificial membrane-bonded phases. , 1989, Analytical biochemistry.

[21]  R. Guy,et al.  Mechanism of percutaneous penetration enhancement : effect of n-alkanols on the permeability barrier of hairless mouse skin , 1990 .

[22]  R. Jakobsen,et al.  An Algorithm for the Reproducible Spectral Subtraction of Water from the FT-IR Spectra of Proteins in Dilute Solutions and Adsorbed Monolayers , 1986 .

[23]  J. Kauppinen.  Chapter 4 – Fourier Self-Deconvolution in Spectroscopy , 1983 .

[24]  H. Mantsch,et al.  Resolution enhancement of infrared spectra of biological systems , 1986 .

[25]  R. Bracewell.  The Fourier Transform and Its Applications , 1966 .

[26]  W. F. Maddams,et al.  The Use of Fourier Deconvolution in Infrared Spectroscopy. Part I: Studies with Synthetic Single-Peak Systems , 1987 .

[27]  H. Mantsch,et al.  Noise in Fourier self-deconvolution. , 1981, Applied optics.

[28]  R. Lewis,et al.  Subgel phases of n-saturated diacylphosphatidylcholines: a Fourier-transform infrared spectroscopic study. , 1990, Biochemistry.

[29]  R. Bracewell.  The Fourier transform. , 1989, Scientific American.

[30]  E. M. Suzuki,et al.  Forensic Science Applications of Diffuse Reflectance Infrared Fourier Transform Spectroscopy (DRIFTS): I. Principles, Sampling Methods, and Advantages , 1986 .

[31]  P. Haris,et al.  Fourier transform infrared spectroscopic studies of lipids, polypeptides and proteins , 1989 .