Folate levels modulate oncogene-induced replication stress and tumorigenicity
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B. Kerem | R. Karni | A. Bester | D. Shewach | Noa Lamm | M. Im | Karin Maoz
[1] Raquel Herrador,et al. Rad51-mediated replication fork reversal is a global response to genotoxic treatments in human cells , 2015, The Journal of cell biology.
[2] J. Diffley,et al. DNA Replication and Oncogene-Induced Replicative Stress , 2014, Current Biology.
[3] T. Helleday,et al. Increased replication initiation and conflicts with transcription underlie Cyclin E-induced replication stress , 2013, Oncogene.
[4] Yehuda G Assaraf,et al. Antifolates in cancer therapy: structure, activity and mechanisms of drug resistance. , 2012, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.
[5] C. Swanton,et al. Cancer chromosomal instability: therapeutic and diagnostic challenges , 2012, EMBO reports.
[6] B. Kerem,et al. The complex basis underlying common fragile site instability in cancer. , 2012, Trends in genetics : TIG.
[7] Michael Fenech,et al. Folate (vitamin B9) and vitamin B12 and their function in the maintenance of nuclear and mitochondrial genome integrity. , 2012, Mutation research.
[8] A. Antony,et al. Influence of Physiologic Folate Deficiency on Human Papillomavirus Type 16 (HPV16)-harboring Human Keratinocytes in Vitro and in Vivo* , 2012, The Journal of Biological Chemistry.
[9] B. Kerem,et al. Nucleotide Deficiency Promotes Genomic Instability in Early Stages of Cancer Development , 2011, Cell.
[10] A. Barabasi,et al. Interactome Networks and Human Disease , 2011, Cell.
[11] D. Hanahan,et al. Hallmarks of Cancer: The Next Generation , 2011, Cell.
[12] S. Duthie. Folate and cancer: how DNA damage, repair and methylation impact on colon carcinogenesis , 2011, Journal of Inherited Metabolic Disease.
[13] T. Halazonetis,et al. Genomic instability — an evolving hallmark of cancer , 2010, Nature Reviews Molecular Cell Biology.
[14] T. Helleday,et al. Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair , 2010, Molecular cell.
[15] R. Weinshilboum,et al. Methotrexate/6-mercaptopurine maintenance therapy influences the risk of a second malignant neoplasm after childhood acute lymphoblastic leukemia: results from the NOPHO ALL-92 study. , 2009, Blood.
[16] M. Debatisse,et al. Replication fork movement sets chromatin loop size and origin choice in mammalian cells , 2008, Nature.
[17] M. Moyer,et al. The response of human colonocytes to folate deficiency in vitro: functional and proteomic analyses. , 2008, Journal of proteome research.
[18] Robert A. Weinberg,et al. Ras oncogenes: split personalities , 2008, Nature Reviews Molecular Cell Biology.
[19] A. Papavassiliou,et al. Oncogene-induced replication stress preferentially targets common fragile sites in preneoplastic lesions. A genome-wide study , 2008, Oncogene.
[20] Jiri Bartek,et al. An Oncogene-Induced DNA Damage Model for Cancer Development , 2008, Science.
[21] Xin Quan Ge,et al. Dormant origins licensed by excess Mcm2-7 are required for human cells to survive replicative stress. , 2007, Genes & development.
[22] D. Gillespie,et al. Chk1 regulates the density of active replication origins during the vertebrate S phase , 2007, The EMBO journal.
[23] B. Robinson,et al. Mismatched nucleotides as the lesions responsible for radiosensitization with gemcitabine: a new paradigm for antimetabolite radiosensitizers , 2007, Molecular Cancer Therapeutics.
[24] Y. Assaraf. Molecular basis of antifolate resistance , 2007, Cancer and Metastasis Reviews.
[25] J. Weissenbach,et al. DNA replication origin interference increases the spacing between initiation events in human cells. , 2006, Molecular biology of the cell.
[26] Aaron Bensimon,et al. Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication , 2006, Nature.
[27] Aphrothiti J Fikaris,et al. Ras induces chromosome instability and abrogation of the DNA damage response. , 2006, Cancer research.
[28] X. Castellsagué,et al. The role of diet and nutrition in cervical carcinogenesis: A review of recent evidence , 2005, International journal of cancer.
[29] M. Fenech,et al. Folic acid deficiency increases chromosomal instability, chromosome 21 aneuploidy and sensitivity to radiation-induced micronuclei. , 2005, Mutation research.
[30] B. Clurman,et al. Cyclin E in normal and neoplastic cell cycles , 2005, Oncogene.
[31] T. Ørntoft,et al. DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis , 2005, Nature.
[32] Dimitris Kletsas,et al. Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions , 2005, Nature.
[33] Jiri Bartek,et al. Cell-cycle checkpoints and cancer , 2004, Nature.
[34] Bruce Stillman,et al. Deregulation of cyclin E in human cells interferes with prereplication complex assembly , 2004, The Journal of cell biology.
[35] Young-In Kim. Role of folate in colon cancer development and progression. , 2003, The Journal of nutrition.
[36] Aaron Bensimon,et al. Dynamics of DNA Replication in Mammalian Somatic Cells Nucleotide Pool Modulates Origin Choice and Interorigin Spacing , 2003, Cell.
[37] L. Bailey,et al. Relationship of folate to colorectal and cervical cancer: review and recommendations for practitioners. , 2002, Journal of the American Dietetic Association.
[38] B. Ames,et al. Are vitamin and mineral deficiencies a major cancer risk? , 2002, Nature Reviews Cancer.
[39] Sang-Woon Choi,et al. Folate status: effects on pathways of colorectal carcinogenesis. , 2002, The Journal of nutrition.
[40] M. Gammon,et al. Nutrient intake and risk of subtypes of esophageal and gastric cancer. , 2001, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
[41] S. Blum,et al. Folate Deficiency In Vitro Induces Uracil Misincorporation and DNA Hypomethylation and Inhibits DNA Excision Repair in Immortalized Normal Human Colon Epithelial Cells , 2000, Nutrition and cancer.
[42] S. Duthie,et al. DNA stability and genomic methylation status in colonocyte isolated from methyl-donor-deficient rats , 2000, European journal of nutrition.
[43] A. Miller,et al. Dietary folate consumption and breast cancer risk. , 2000, Journal of the National Cancer Institute.
[44] I. Pogribny,et al. Uracil misincorporation, DNA strand breaks, and gene amplification are associated with tumorigenic cell transformation in folate deficient/repleted Chinese hamster ovary cells. , 1999, Cancer letters.
[45] Y. Kim,et al. Folate and cancer prevention: a new medical application of folate beyond hyperhomocysteinemia and neural tube defects. , 1999, Nutrition reviews.
[46] S. Reed,et al. Deregulated cyclin E induces chromosome instability , 1999, Nature.
[47] G A Colditz,et al. A prospective study of folate intake and the risk of breast cancer. , 1999, JAMA.
[48] Y. Kim,et al. Folate and carcinogenesis: evidence, mechanisms, and implications. , 1999, The Journal of nutritional biochemistry.
[49] K. Kinzler,et al. Genetic instabilities in human cancers , 1998, Nature.
[50] S. Duthie,et al. DNA instability (strand breakage, uracil misincorporation, and defective repair) is increased by folic acid depletion in human lymphocytes in vitro , 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[51] C. Harley,et al. Extension of life-span by introduction of telomerase into normal human cells. , 1998, Science.
[52] I. Pogribny,et al. Presence and consequence of uracil in preneoplastic DNA from folate/methyl-deficient rats. , 1997, Carcinogenesis.
[53] P. McMillan,et al. Uracil misincorporation in human DNA detected using single cell gel electrophoresis. , 1997, Carcinogenesis.
[54] B. P. Eynon,et al. 'Spontaneous' genetic damage in man: evaluation of interindividual variability, relationship among markers of damage, and influence of nutritional status. , 1997, Mutation research.
[55] B. Ames,et al. Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[56] I. Rosenberg,et al. Folate synthesized by bacteria in the human upper small intestine is assimilated by the host. , 1996, Gastroenterology.
[57] E. Rimm,et al. Alcohol, low-methionine--low-folate diets, and risk of colon cancer in men. , 1995, Journal of the National Cancer Institute.
[58] A. Giaccia,et al. The human Ha-ras oncogene induces genomic instability in murine fibroblasts within one cell cycle. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[59] S. J. James,et al. Diet-induced DNA damage and altered nucleotide metabolism in lymphocytes from methyl-donor-deficient rats. , 1989, Carcinogenesis.
[60] S. Mannava,et al. Depletion of deoxyribonucleotide pools is an endogenous source of DNA damage in cells undergoing oncogene-induced senescence. , 2013, The American journal of pathology.
[61] J. Herrick,et al. Introduction to molecular combing: genomics, DNA replication, and cancer. , 2009, Methods in molecular biology.
[62] C. Coopersmith,et al. Epithelial cells , 1991 .
[63] W. R. Kiser,et al. Folate deficiency. , 1999, Southern medical journal.
[64] B. Shane. Folylpolyglutamate synthesis and role in the regulation of one-carbon metabolism. , 1989, Vitamins and hormones.
[65] J. Reidy,et al. Increased chromosome fragility as a consequence of blood folate levels, smoking status, and coffee consumption , 1989, Environmental and molecular mutagenesis.
[66] J. Cruz. Precancerous lesions. , 1989, Medical Section proceedings : the ... annual Meeting of the Medical Section of the American Council of Life Insurance. American Council of Life Insurance. Medical Section. Meeting.
[67] I. Eto,et al. Role of vitamin B12 and folate deficiencies in carcinogenesis. , 1986, Advances in experimental medicine and biology.
[68] the original work is properly cited. , 2022 .