Surgical margin determination in head and neck oncology: Current clinical practice. The results of an International American Head and Neck Society Member Survey

Our aim was to investigate the ways in which surgeons who perform head and neck ablative procedures on a regular basis define margins, how they use frozen sections to evaluate margins, and the effect of chemoradiation on determining tumor margins.

[1]  J G Batsakis,et al.  Surgical excision margins: a pathologist's perspective. , 1999, Advances in anatomic pathology.

[2]  R H Hruban,et al.  Molecular assessment of histopathological staging in squamous-cell carcinoma of the head and neck. , 1995, The New England journal of medicine.

[3]  H. Biller,et al.  Reliability of frozen section diagnosis in head and neck neoplasms , 1984, The Laryngoscope.

[4]  P. Slootweg,et al.  Treatment failure and margin status in head and neck cancer. A critical view on the potential value of molecular pathology. , 2002, Oral oncology.

[5]  S. Monfardini,et al.  A pathologic assessment of tumor residue and stromal changes after intraarterial chemotherapy for head and neck carcinomas. A study on serial sections of the whole surgical specimen , 1989 .

[6]  R. Gandour-Edwards,et al.  Accuracy of intraoperative frozen section diagnosis in head and neck surgery: Experience at a university medical center , 1993, Head & neck.

[7]  R A Robinson,et al.  Quantification of surgical margin shrinkage in the oral cavity , 1997, Head & neck.

[8]  A. De Benedetti,et al.  Detection of the proto-oncogene eIF4E in larynx and hypopharynx cancers. , 1999, Archives of otolaryngology--head & neck surgery.

[9]  K I Bland,et al.  The prognostic and therapeutic value of frozen section determinations in the surgical treatment of squamous carcinoma of the head and neck. , 1978, American journal of surgery.

[10]  J. Batsakis,et al.  Microscopic cut-through of cancer in the surgical treatment of squamous carcinoma of the tongue. Prognostic and therapeutic implications. , 1986, American journal of surgery.

[11]  S. Bogart Histologic tumor regression grades in squamous cell carcinoma of the head and neck after preoperative radiochemotherapy , 1989 .

[12]  C. Kerawala,et al.  Relocating the site of frozen sections—Is there room for improvement? , 2001, Head & neck.

[13]  E. Strong,et al.  The significance of "positive" margins in surgically resected epidermoid carcinomas. , 1978, Head & neck surgery.

[14]  J. Holzner,et al.  Histologic tumor regression grades in squamous cell carcinoma of the head and neck after preoperative radiochemotherapy , 1989, Cancer.

[15]  C. O'brien,et al.  Influence of condition of surgical margins on local recurrence and disease-specific survival in oral and oropharyngeal cancer. , 2003, The British journal of oral & maxillofacial surgery.

[16]  R. Spiro,et al.  Pattern of invasion and margin assessment in patients with oral tongue cancer , 1999, Head & neck.

[17]  R. Ord,et al.  Accuracy of frozen sections in assessing margins in oral cancer resection. , 1997, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[18]  E. Strong,et al.  Significance of positive margins in oral cavity squamous carcinoma. , 1990, American journal of surgery.