Australia antigen and polyarteritis nodosa.

We have previously reported detection of Au-SH antigen in six of seven clinically and histologically characteristic cases of polyarteritis nodosa (PAN). 1 Independently, Gocke et al found this antigen in four of 11 cases. 2 In this communication, we shall review the clinical and serological findings on 15 patients with PAN in whom Au-SH antigen or antibody by agar gel diffusion (AGD), 3 immunoelectroosmophoresis (IEOP), 4 by passive hemagglutination (HA), and hemagglutination inhibition (HAI). 5 Results The Au-SH antigen was found in seven out of 15 cases of PAN in Lyon, France. Antigen was not detected in most cases if the disease had persisted for many years. A total of 14 cases of PAN with detectable Au-SH antigen and one case with Au-SH antibody were studied with the cooperation of several colleagues. Detailed serologic data on these cases are summarized in the Table. Antigen was detected during the first 3

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