Paracrine signal emanating from stressed cardiomyocytes aggravates inflammatory microenvironment in diabetic cardiomyopathy

[1]  K. Tracey,et al.  Post-Translational Modification of HMGB1 Disulfide Bonds in Stimulating and Inhibiting Inflammation , 2021, Cells.

[2]  André F. Rendeiro,et al.  Hyperglycemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis , 2021, Circulation.

[3]  B. Joddar,et al.  Cardioprotective Effect of Glycyrrhizin on Myocardial Remodeling in Diabetic Rats , 2021, Biomolecules.

[4]  Juhong Yang,et al.  Vildagliptin Attenuates Myocardial Dysfunction and Restores Autophagy via miR-21/SPRY1/ERK in Diabetic Mice Heart , 2021, Frontiers in Pharmacology.

[5]  Kristin M. French,et al.  Xbp1s-FoxO1 axis governs lipid accumulation and contractile performance in heart failure with preserved ejection fraction , 2021, Nature Communications.

[6]  Jun Ren,et al.  Endoplasmic reticulum stress and unfolded protein response in cardiovascular diseases , 2021, Nature Reviews Cardiology.

[7]  T. Madhusudhan,et al.  The MEK inhibitor U0126 ameliorates diabetic cardiomyopathy by restricting XBP1's phosphorylation dependent SUMOylation , 2021, International journal of biological sciences.

[8]  A. Tomilin,et al.  Functional Diversity of Non-Histone Chromosomal Protein HmgB1 , 2020, International journal of molecular sciences.

[9]  J. Ge,et al.  Cardiomyocyte-restricted high-mobility group box 1 (HMGB1) deletion leads to small heart and glycolipid metabolic disorder through GR/PGC-1α signalling , 2020, Cell death discovery.

[10]  Sandeep R. Das,et al.  2020 Expert Consensus Decision Pathway on Novel Therapies for Cardiovascular Risk Reduction in Patients With Type 2 Diabetes: A Report of the American College of Cardiology Solution Set Oversight Committee. , 2020, Journal of the American College of Cardiology.

[11]  Aleksandra Stojanovic,et al.  Dipeptidyl peptidase-4 inhibitors as new tools for cardioprotection , 2020, Heart Failure Reviews.

[12]  Young Hun Kim,et al.  Immunological Significance of HMGB1 Post-Translational Modification and Redox Biology , 2020, Frontiers in Immunology.

[13]  E. Cartwright,et al.  Targeting mir128-3p alleviates myocardial insulin resistance and prevents ischemia-induced heart failure , 2020, eLife.

[14]  L. Cai,et al.  Mechanisms of diabetic cardiomyopathy and potential therapeutic strategies: preclinical and clinical evidence , 2020, Nature Reviews Cardiology.

[15]  D. Grimm,et al.  Bioactive Candy: Effects of Licorice on the Cardiovascular System , 2019, Foods.

[16]  Steven P Jones,et al.  A Physiological Biomimetic Culture System for Pig and Human Heart Slices. , 2019, Circulation research.

[17]  J. Ge,et al.  HMGB1 enhances mechanical stress-induced cardiomyocyte hypertrophy in vitro via the RAGE/ERK1/2 signaling pathway , 2019, International journal of molecular medicine.

[18]  Kavita Sharma,et al.  Nitrosative stress drives heart failure with preserved ejection fraction , 2019, Nature.

[19]  Yanyan Qi,et al.  Vildagliptin inhibits high free fatty acid (FFA)-induced NLRP3 inflammasome activation in endothelial cells , 2019, Artificial cells, nanomedicine, and biotechnology.

[20]  E. Cartwright,et al.  Pak2 as a Novel Therapeutic Target for Cardioprotective Endoplasmic Reticulum Stress Response , 2019, Circulation research.

[21]  D. Tilley,et al.  The Role of Leukocytes in Diabetic Cardiomyopathy , 2018, Front. Physiol..

[22]  X. Palomer,et al.  Emerging Actors in Diabetic Cardiomyopathy: Heartbreaker Biomarkers or Therapeutic Targets? , 2018, Trends in pharmacological sciences.

[23]  S. Kheirouri,et al.  Changes of Insulin Resistance and Adipokines Following Supplementation with Glycyrrhiza Glabra L. Extract in Combination with a Low-Calorie Diet in Overweight and Obese Subjects: a Randomized Double Blind Clinical Trial , 2018, Advanced pharmaceutical bulletin.

[24]  M. Lindsey,et al.  Cardiac macrophage biology in the steady-state heart, the aging heart, and following myocardial infarction , 2017, Translational research : the journal of laboratory and clinical medicine.

[25]  L. Nedosugova,et al.  Proinflammatory monocyte polarization in type 2 diabetes mellitus and coronary heart disease , 2017 .

[26]  S. Paczesny,et al.  Editorial: Danger Signals Triggering Immune Response and Inflammation , 2017, Front. Immunol..

[27]  M. Volpe,et al.  An overview of the inflammatory signalling mechanisms in the myocardium underlying the development of diabetic cardiomyopathy. , 2017, Cardiovascular research.

[28]  Toru Suzuki,et al.  ER Stress Protein CHOP Mediates Insulin Resistance by Modulating Adipose Tissue Macrophage Polarity. , 2017, Cell reports.

[29]  N. Angadi,et al.  Effect of dipeptidyl peptidase 4 inhibitors on acute and subacute models of inflammation in male Wistar rats: An experimental study , 2017, International journal of applied & basic medical research.

[30]  Y. Huang,et al.  Endoplasmic reticulum stress-induced neuronal inflammatory response and apoptosis likely plays a key role in the development of diabetic encephalopathy , 2016, Oncotarget.

[31]  S. Palaniyandi,et al.  Modulation of Macrophage Polarization and HMGB1-TLR2/TLR4 Cascade Plays a Crucial Role for Cardiac Remodeling in Senescence-Accelerated Prone Mice , 2016, PloS one.

[32]  J. Ge,et al.  Extracellular high‐mobility group box 1 mediates pressure overload‐induced cardiac hypertrophy and heart failure , 2015, Journal of cellular and molecular medicine.

[33]  M. Andrassy,et al.  Critical role of RAGE and HMGB1 in inflammatory heart disease , 2015, Proceedings of the National Academy of Sciences.

[34]  N. Câmara,et al.  Macrophages During the Fibrotic Process: M2 as Friend and Foe , 2015, Front. Immunol..

[35]  K. Hoeflich,et al.  p21-Activated Kinase 2 Regulates Endothelial Development and Function through the Bmk1/Erk5 Pathway , 2015, Molecular and Cellular Biology.

[36]  X. Xiang,et al.  Chop deficiency prevents UUO-induced renal fibrosis by attenuating fibrotic signals originated from Hmgb1/TLR4/NFκB/IL-1β signaling , 2015, Cell Death and Disease.

[37]  Ryan A Frieler,et al.  Immune cell and other noncardiomyocyte regulation of cardiac hypertrophy and remodeling. , 2015, Circulation.

[38]  Spiros Denaxas,et al.  Type 2 diabetes and incidence of cardiovascular diseases: a cohort study in 1·9 million people , 2015, The Lancet.

[39]  Jun Ren,et al.  Endoplasmic reticulum stress and protein quality control in diabetic cardiomyopathy. , 2015, Biochimica et biophysica acta.

[40]  Heshui Wu,et al.  PARP-1 Mediates LPS-Induced HMGB1 Release by Macrophages through Regulation of HMGB1 Acetylation , 2014, The Journal of Immunology.

[41]  Renu Malhotra,et al.  IHC Profiler: An Open Source Plugin for the Quantitative Evaluation and Automated Scoring of Immunohistochemistry Images of Human Tissue Samples , 2014, PloS one.

[42]  K. Tracey,et al.  JAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation , 2014, Proceedings of the National Academy of Sciences.

[43]  Yawei Xu,et al.  Increased serum HMGB1 related with HbA1c in coronary artery disease with type 2 diabetes mellitus. , 2013, International journal of cardiology.

[44]  M. Nagata,et al.  The hyperglycemia stimulated myocardial endoplasmic reticulum (ER) stress contributes to diabetic cardiomyopathy in the transgenic non-obese type 2 diabetic rats: a differential role of unfolded protein response (UPR) signaling proteins. , 2013, The international journal of biochemistry & cell biology.

[45]  Shirin Doroudgar,et al.  New concepts of endoplasmic reticulum function in the heart: programmed to conserve. , 2013, Journal of molecular and cellular cardiology.

[46]  L. Wold,et al.  Metabolic dysfunction in diabetic cardiomyopathy , 2013, Heart Failure Reviews.

[47]  P. Vandenabeele,et al.  ER stress-induced inflammation: does it aid or impede disease progression? , 2012, Trends in molecular medicine.

[48]  Y. Kido,et al.  DPP4 inhibitor vildagliptin preserves b -cell mass through amelioration of endoplasmic reticulum stress in C/EBPB transgenic mice , 2012 .

[49]  H. Nishitoh CHOP is a multifunctional transcription factor in the ER stress response. , 2012, Journal of biochemistry.

[50]  舟山 哲 Cardiac nuclear high mobility group box 1 prevents the development of cardiac hypertrophy and heart failure , 2012 .

[51]  L. Velloso,et al.  Endoplasmic reticulum stress, obesity and diabetes. , 2012, Trends in molecular medicine.

[52]  Y. Oike,et al.  C/EBP Homologous Protein Deficiency Attenuates Myocardial Reperfusion Injury by Inhibiting Myocardial Apoptosis and Inflammation , 2011, Arteriosclerosis, thrombosis, and vascular biology.

[53]  A. Chakraborti,et al.  Ameliorative effects of glycyrrhizin on streptozotocin‐induced diabetes in rats , 2011, The Journal of pharmacy and pharmacology.

[54]  I. Komuro,et al.  Endoplasmic reticulum stress as a therapeutic target in cardiovascular disease. , 2010, Circulation research.

[55]  Sarah Hummasti,et al.  Endoplasmic Reticulum Stress and Inflammation in Obesity and Diabetes , 2010, Circulation research.

[56]  M. Andrassy,et al.  HMGB1: the missing link between diabetes mellitus and heart failure , 2010, Basic Research in Cardiology.

[57]  I. Komuro,et al.  Ablation of C/EBP Homologous Protein Attenuates Endoplasmic Reticulum–Mediated Apoptosis and Cardiac Dysfunction Induced by Pressure Overload , 2010, Circulation.

[58]  Randal J. Kaufman,et al.  From endoplasmic-reticulum stress to the inflammatory response , 2008, Nature.

[59]  Aiqing He,et al.  The Unfolded Protein Response Is an Important Regulator of Inflammatory Genes in Endothelial Cells , 2006, Arteriosclerosis, thrombosis, and vascular biology.

[60]  L. Wold,et al.  Oxidative stress and stress signaling: menace of diabetic cardiomyopathy , 2005, Acta Pharmacologica Sinica.

[61]  M. Hori,et al.  Prolonged Endoplasmic Reticulum Stress in Hypertrophic and Failing Heart After Aortic Constriction: Possible Contribution of Endoplasmic Reticulum Stress to Cardiac Myocyte Apoptosis , 2004, Circulation.

[62]  D. Bell,et al.  Diabetic cardiomyopathy. , 2003, Diabetes care.

[63]  K. Saksela,et al.  Cdc42/Rac1-Mediated Activation Primes PAK2 for Superactivation by Tyrosine Phosphorylation , 2002, Molecular and Cellular Biology.

[64]  Thomas D. Schmittgen,et al.  Real-Time Quantitative PCR , 2002 .