Semantic representation and processing of hypoglycemic events derived from wearable sensor data

Diabetes Type 1 is a metabolic disease which results in a lack of insulin production, causing high glucose levels in the blood. It is crucial for diabetic patients to balance this glucose level, and they depend on external substances to do so. In order to keep this level under control, they usually need to resort to invasive glucose control methods, such as taking a sample drop of blood from their finger and have it analyzed. Recently, other directions emerged to offer alternative ways to estimate glucose level, using indirect sensor measurements including ECG monitoring and other physiological parameters. This paper showcases a framework for inferring semantically annotated glycemic events on the patient, which leverages data from mobile wearable sensors deployed on a sport-belt. This work is part of the D1namo project for non-invasive diabetes monitoring, and focuses on the representation and query processing of the data produced by the wearable sensors, using semantic technologies and vocabularies that extend existing Web standards. Furthermore, this work shows how different layers of data, from raw measurements to complex events can be represented and linked in this framework, and experimental evidence is provided of how these layers can be efficiently exploited using an RDF Stream Processing engine.

[1]  Federica Paganelli,et al.  An Ontology-Based Context Model for Home Health Monitoring and Alerting in Chronic Patient Care Networks , 2007, 21st International Conference on Advanced Information Networking and Applications Workshops (AINAW'07).

[2]  T. Laitinen,et al.  Electrocardiographic Alterations during Hyperinsulinemic Hypoglycemia in Healthy Subjects , 2008, Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc.

[3]  Daniel P. Siewiorek,et al.  Wearable context-aware food recognition for calorie monitoring , 2008, 2008 12th IEEE International Symposium on Wearable Computers.

[4]  Ilkka Korhonen,et al.  Detection of Daily Activities and Sports With Wearable Sensors in Controlled and Uncontrolled Conditions , 2008, IEEE Transactions on Information Technology in Biomedicine.

[5]  Daniele Braga,et al.  C-SPARQL: SPARQL for continuous querying , 2009, WWW '09.

[6]  Chris D. Nugent,et al.  Ontology-based activity recognition in intelligent pervasive environments , 2009, Int. J. Web Inf. Syst..

[7]  Alasdair J. G. Gray,et al.  Enabling Ontology-Based Access to Streaming Data Sources , 2010, SEMWEB.

[8]  Stephen S. Intille,et al.  Using wearable activity type detection to improve physical activity energy expenditure estimation , 2010, UbiComp.

[9]  Claudio Bettini,et al.  Is ontology-based activity recognition really effective? , 2011, 2011 IEEE International Conference on Pervasive Computing and Communications Workshops (PERCOM Workshops).

[10]  Wolf-Joachim Fischer,et al.  Food Intake Activity Detection Using a Wearable Microphone System , 2011, 2011 Seventh International Conference on Intelligent Environments.

[11]  Danh Le Phuoc,et al.  A Native and Adaptive Approach for Unified Processing of Linked Streams and Linked Data , 2011, SEMWEB.

[12]  Thomas Eiter,et al.  Linked Stream Data Processing Engines: Facts and Figures , 2012, SEMWEB.

[13]  Peter F. Patel-Schneider,et al.  OWL 2 Web Ontology Language Primer (Second Edition) , 2012 .

[14]  Amit P. Sheth,et al.  The SSN ontology of the W3C semantic sensor network incubator group , 2012, J. Web Semant..

[15]  K. Turksoy,et al.  Multivariable adaptive closed-loop control of an artificial pancreas without meal and activity announcement. , 2013, Diabetes technology & therapeutics.

[16]  Morwenna Kirwan,et al.  Diabetes Self-Management Smartphone Application for Adults With Type 1 Diabetes: Randomized Controlled Trial , 2013, Journal of medical Internet research.

[17]  Riyanarto Sarno,et al.  Weighted Ontology and weighted tree similarity algorithm for diagnosing Diabetes Mellitus , 2013, 2013 International Conference on Computer, Control, Informatics and Its Applications (IC3INA).

[18]  Mark Hennessy,et al.  A framework and ontology for mobile sensor platforms in home health management , 2013, 2013 1st International Workshop on the Engineering of Mobile-Enabled Systems (MOBS).

[19]  Eleni I. Georga,et al.  Wearable systems and mobile applications for diabetes disease management , 2014 .

[20]  Ole K. Hejlesen,et al.  A Novel Algorithm for Prediction and Detection of Hypoglycemia Based on Continuous Glucose Monitoring and Heart Rate Variability in Patients With Type 1 Diabetes , 2014, Journal of diabetes science and technology.

[21]  Jean-Marc Vesin,et al.  Adaptive Mathematical Morphology for QRS fiducial points detection in the ECG , 2014, Computing in Cardiology 2014.

[22]  D. BretonMarc,et al.  Adding heart rate signal to a control-to-range artificial pancreas system improves the protection against hypoglycemia during exercise in type 1 diabetes. , 2014 .

[23]  Pradeep Kumar Ray,et al.  Validating an ontology-based algorithm to identify patients with Type 2 Diabetes Mellitus in Electronic Health Records , 2014, Int. J. Medical Informatics.

[24]  L. Tarassenko,et al.  Development of a Real-Time Smartphone Solution for the Management of Women With or at High Risk of Gestational Diabetes , 2014, Journal of diabetes science and technology.

[25]  Marc D Breton,et al.  Adding heart rate signal to a control-to-range artificial pancreas system improves the protection against hypoglycemia during exercise in type 1 diabetes. , 2014, Diabetes technology & therapeutics.

[26]  Yves Raimond,et al.  RDF 1.1 Primer , 2014 .

[27]  Sandra I. Sobel,et al.  Accuracy of a Novel Noninvasive Multisensor Technology to Estimate Glucose in Diabetic Subjects During Dynamic Conditions , 2014, Journal of diabetes science and technology.

[28]  Melanie Senior,et al.  Novartis signs up for Google smart lens , 2014, Nature Biotechnology.

[29]  Albert Brugués de la Torre,et al.  Processing Diabetes Mellitus Composite Events in MAGPIE , 2016, Journal of Medical Systems.

[30]  Young Seol Kim,et al.  A Smartphone Application Significantly Improved Diabetes Self-Care Activities with High User Satisfaction , 2015, Diabetes & metabolism journal.

[31]  Jesper Fleischer,et al.  Combining Information of Autonomic Modulation and CGM Measurements Enables Prediction and Improves Detection of Spontaneous Hypoglycemic Events , 2014, Journal of diabetes science and technology.

[32]  Danh Le Phuoc,et al.  Towards Enriching CQELS with Complex Event Processing and Path Navigation , 2015, HiDeSt@KI.

[33]  Karl Aberer,et al.  Detection of Hypoglycemic Events through Wearable Sensors , 2016, SEMPER@ESWC.