On quantitative microwave tomography of female breast

Microwave tomography deserves attention in biomedical imaging, owing to its potential capability of providing a morphological and functional assessment of the inspected tissues. However, such a goal requires the not trivial task of solving a non linear inverse scattering problem. In this paper, the factors afiecting the complexity of the inverse problem are exploited to trace guidelines aimed at setting the matching ∞uid, the frequency range and the number of probes in such a way that the dielectric parameters of female breast tissues can be reliably retrieved. Examples, concerning 2D realistic numerical phantoms obtained by NMR images, are given to asses a posteriori the efiectiveness of the proposed guidelines.

[1]  Ka-Ma Huang,et al.  MICROWAVE IMAGING A BURIED OBJECT BY THE GA AND USING THE S11 PARAMETER , 2008 .

[2]  M. Lindstrom,et al.  A large-scale study of the ultrawideband microwave dielectric properties of normal breast tissue obtained from reduction surgeries , 2007, Physics in medicine and biology.

[3]  Roger W. Johnson,et al.  An Introduction to the Bootstrap , 2001 .

[4]  T. Isernia,et al.  On Simple Methods for Shape Reconstruction of Unknown Scatterers , 2007, IEEE Transactions on Antennas and Propagation.

[5]  D. Colton,et al.  The linear sampling method in inverse electromagnetic scattering theory , 2003 .

[6]  D. W. van der Weide,et al.  Microwave imaging via space-time beamforming: experimental investigation of tumor detection in multilayer breast phantoms , 2004, IEEE Transactions on Microwave Theory and Techniques.

[7]  G. Franceschetti,et al.  On the degrees of freedom of scattered fields , 1989 .

[8]  Lorenzo Crocco,et al.  Improving the reconstruction capabilities in inverse scattering problems by exploitation of close-proximity setups , 1999 .

[9]  Vito Pascazio,et al.  On the local minima in a tomographic imaging technique , 2001, IEEE Trans. Geosci. Remote. Sens..

[10]  Takashi Takenaka,et al.  A Breast Imaging Model Using Microwaves and a Time Domain Three Dimensional Reconstruction Method , 2009 .

[11]  C. Gabriel The Dielectric Properties of Tissues , 2000 .

[12]  P. Huynh,et al.  The false-negative mammogram. , 1998, Radiographics : a review publication of the Radiological Society of North America, Inc.

[13]  A. Abbosh,et al.  Early breast cancer detection using hybrid imaging modality , 2009, 2009 IEEE Antennas and Propagation Society International Symposium.

[14]  W. Chew,et al.  A frequency-hopping approach for microwave imaging of large inhomogeneous bodies , 1995, IEEE Antennas and Propagation Society International Symposium. 1995 Digest.

[15]  K. T. Mathew,et al.  ACTIVE MICROWAVE IMAGING FOR BREAST CANCER DETECTION , 2006 .

[16]  A. Abubakar,et al.  Microwave Biomedical Data Inversion Using the Finite-Difference Contrast Source Inversion Method , 2009, IEEE Transactions on Antennas and Propagation.

[17]  C Gabriel,et al.  Tissue equivalent material for hand phantoms. , 2007, Physics in medicine and biology.

[18]  C. Balanis Advanced Engineering Electromagnetics , 1989 .

[19]  E.C. Fear,et al.  Tissue sensing adaptive Radar for breast cancer detection-investigations of an improved skin-sensing method , 2006, IEEE Transactions on Microwave Theory and Techniques.

[20]  K. Paulsen,et al.  Nonlinear Microwave Imaging for Breast-Cancer Screening Using Gauss–Newton's Method and the CGLS Inversion Algorithm , 2007, IEEE Transactions on Antennas and Propagation.

[21]  A. Tikhonov,et al.  Numerical Methods for the Solution of Ill-Posed Problems , 1995 .

[22]  T. Isernia,et al.  Microwave tomography of breast cancer: A feasibility study , 2006, 2006 First European Conference on Antennas and Propagation.

[23]  M. Lindstrom,et al.  A large-scale study of the ultrawideband microwave dielectric properties of normal, benign and malignant breast tissues obtained from cancer surgeries , 2007, Physics in medicine and biology.

[24]  P. M. Berg,et al.  Contrast Source Inversion Method: State of Art , 2001 .

[25]  L. E. Larsen,et al.  Limitations of Imaging with First-Order Diffraction Tomography , 1984 .

[26]  T. Isernia,et al.  Degree of nonlinearity and a new solution procedure in scalar two-dimensional inverse scattering problems. , 2001, Journal of the Optical Society of America. A, Optics, image science, and vision.

[27]  David Girbau,et al.  Simulated and Experimental Investigation of Microwave Imaging Using UWB , 2009 .

[28]  A. Gelfand,et al.  Predicting the cumulative risk of false-positive mammograms. , 2000, Journal of the National Cancer Institute.

[29]  Lorenzo Crocco,et al.  New tools and series for forward and inverse scattering problems in lossy media , 2004, IEEE Geoscience and Remote Sensing Letters.

[30]  Soon Yim Tan,et al.  A novel method for microwave breast cancer detection , 2008 .

[31]  T. Isernia,et al.  On the Effect of Support Estimation and of a New Model in 2-D Inverse Scattering Problems , 2007, IEEE Transactions on Antennas and Propagation.

[32]  John H. Booske,et al.  Dielectric characterization of carbon nanotube contrast agents for microwave breast cancer detection , 2009, 2009 IEEE Antennas and Propagation Society International Symposium.

[33]  S.H. Zainud-Deen,et al.  Breast cancer detection using a hybrid Finite difference frequency domain and particle swarm optimization techniques , 2008, 2008 National Radio Science Conference.

[34]  Zhi Qi Meng,et al.  Autonomous Genetic Algorithm for Functional Optimization , 2007 .

[35]  Paul M. Meaney,et al.  Microwaves for breast cancer detection , 2003 .

[36]  K. Paulsen,et al.  Initial clinical experience with microwave breast imaging in women with normal mammography. , 2007, Academic radiology.

[37]  Carey M. Rappaport,et al.  Determination of Bolus Dielectric Constant for Optimum Coupling of Microwaves through Skin for Breast Cancer Imaging , 2008 .

[38]  Tommaso Isernia,et al.  Electromagnetic inverse scattering: Retrievable information and measurement strategies , 1997 .

[39]  Mario Bertero,et al.  Introduction to Inverse Problems in Imaging , 1998 .