Upregulation of arginase-II contributes to decreased age-related myocardial contractile reserve

[1]  A. Shoukas,et al.  OxLDL-dependent activation of arginase II is dependent on the LOX-1 receptor and downstream RhoA signaling. , 2011, Atherosclerosis.

[2]  E. Block,et al.  Hypoxic upregulation of arginase II in human lung endothelial cells. , 2010, American journal of physiology. Cell physiology.

[3]  Hae-Young Lee,et al.  Aging and arterial stiffness. , 2010, Circulation journal : official journal of the Japanese Circulation Society.

[4]  U. Klöckner,et al.  NADPH oxidase-derived superoxide impairs calcium transients and contraction in aged murine ventricular myocytes , 2010, Experimental Gerontology.

[5]  A. Shoukas,et al.  Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats. , 2009, Journal of applied physiology.

[6]  G. Heusch,et al.  Inducible Nitric Oxide Synthase Expression and Cardiomyocyte Dysfunction During Sustained Moderate Ischemia in Pigs , 2008, Circulation research.

[7]  D. Christianson,et al.  Arginase and vascular aging. , 2008, Journal of applied physiology.

[8]  A. Shoukas,et al.  Endothelial Arginase II: A Novel Target for the Treatment of Atherosclerosis , 2008, Circulation research.

[9]  D. Berkowitz Myocyte nitroso-redox imbalance in sepsis: NO simple answer. , 2007, Circulation research.

[10]  F. Polticelli,et al.  Nitrosative/oxidative modifications and ageing , 2006, Mechanisms of Ageing and Development.

[11]  D. H. Kim,et al.  Calumenin, a multiple EF-hands Ca2+-binding protein, interacts with ryanodine receptor-1 in rabbit skeletal sarcoplasmic reticulum. , 2006, Biochemical and biophysical research communications.

[12]  A. Shoukas,et al.  Arginase modulates myocardial contractility by a nitric oxide synthase 1-dependent mechanism. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[13]  A. Shoukas,et al.  Knockdown of Arginase I Restores NO Signaling in the Vasculature of Old Rats , 2006, Hypertension.

[14]  H. E. Marshall,et al.  Protein S-nitrosylation: purview and parameters , 2005, Nature Reviews Molecular Cell Biology.

[15]  J. Hare Nitroso-redox balance in the cardiovascular system. , 2004, The New England journal of medicine.

[16]  J. Hare,et al.  Neuronal nitric oxide synthase negatively regulates xanthine oxidoreductase inhibition of cardiac excitation-contraction coupling. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[17]  R. Watson,et al.  Modulation of iNOS activity in age-related cardiac dysfunction. , 2004, Life sciences.

[18]  A. Shoukas,et al.  Arginase Reciprocally Regulates Nitric Oxide Synthase Activity and Contributes to Endothelial Dysfunction in Aging Blood Vessels , 2003, Circulation.

[19]  J. Hare,et al.  The role of nitric oxide in the physiological regulation of Ca2+ cycling. , 2003, Current opinion in drug discovery & development.

[20]  J. Hare Nitric oxide and excitation-contraction coupling. , 2003, Journal of molecular and cellular cardiology.

[21]  A. Shoukas,et al.  Nitric oxide regulation of myocardial contractility and calcium cycling: independent impact of neuronal and endothelial nitric oxide synthases. , 2003, Circulation research.

[22]  C. Leeuwenburgh,et al.  Aging and the Role of Reactive Nitrogen Species , 2002, Annals of the New York Academy of Sciences.

[23]  Joao A. C. Lima,et al.  Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms. , 2002 .

[24]  Santiago Lamas,et al.  Nitrosylation The Prototypic Redox-Based Signaling Mechanism , 2001, Cell.

[25]  L. Kuo,et al.  Constitutive expression of arginase in microvascular endothelial cells counteracts nitric oxide‐mediated vasodilatory function , 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[26]  Sathyanarayana,et al.  Nitric oxide synthase isoform expression in a porcine model of granulation tissue formation. , 2001, Surgery.

[27]  J. Balligand Regulation of cardiac beta-adrenergic response by nitric oxide. , 1999, Cardiovascular research.

[28]  T. Gotoh,et al.  Regulation of the genes for arginase isoforms and related enzymes in mouse macrophages by lipopolysaccharide. , 1999, American journal of physiology. Endocrinology and metabolism.

[29]  D. Bredt,et al.  Nitric oxide synthase in cardiac sarcoplasmic reticulum. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[30]  S. Morris,et al.  Differential regulation of arginases and inducible nitric oxide synthase in murine macrophage cells. , 1998, American journal of physiology. Endocrinology and metabolism.

[31]  F. B. Davis,et al.  Induction of Mn SOD in human monocytes without inflammatory cytokine production by a mutant endotoxin. , 1998, American journal of physiology. Cell physiology.

[32]  M. Creager,et al.  Increased sensitivity to nitric oxide synthase inhibition in patients with heart failure: potentiation of beta-adrenergic inotropic responsiveness. , 1998, Circulation.

[33]  M. Takiguchi,et al.  Molecular cloning of cDNA for nonhepatic mitochondrial arginase (arginase II) and comparison of its induction with nitric oxide synthase in a murine macrophage‐like cell line , 1996, FEBS letters.

[34]  S. Umar,et al.  Nitric oxide and nitric oxide synthase isoforms in the normal, hypertrophic, and failing heart , 2009, Molecular and Cellular Biochemistry.

[35]  Joao A. C. Lima,et al.  Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms , 2002, Nature.