Cell-free and cell-based approaches for bone regeneration

[1]  S. Griffiths,et al.  In vivo performance of simvastatin-loaded electrospun spiral-wound polycaprolactone scaffolds in reconstruction of cranial bone defects in the rat model. , 2009, Journal of biomedical materials research. Part A.

[2]  N. Epstein.  Beta tricalcium phosphate: observation of use in 100 posterolateral lumbar instrumented fusions. , 2009, The spine journal : official journal of the North American Spine Society.

[3]  Christian Jungreuthmayer,et al.  Development of a biomimetic collagen-hydroxyapatite scaffold for bone tissue engineering using a SBF immersion technique. , 2009, Journal of biomedical materials research. Part B, Applied biomaterials.

[4]  M. Rahm,et al.  Clinical and radiographic assessment of transforaminal lumbar interbody fusion using HEALOS collagen-hydroxyapatite sponge with autologous bone marrow aspirate. , 2009, The spine journal : official journal of the North American Spine Society.

[5]  M. McGuire,et al.  Growth factor-mediated treatment of recession defects: a randomized controlled trial and histologic and microcomputed tomography examination. , 2009, Journal of periodontology.

[6]  Casey K Chan,et al.  Cell therapy for bone regeneration--bench to bedside. , 2009, Journal of biomedical materials research. Part B, Applied biomaterials.

[7]  R. Cancedda,et al.  Recruitment of a host's osteoprogenitor cells using exogenous mesenchymal stem cells seeded on porous ceramic. , 2009, Tissue engineering. Part A.

[8]  Stan Gronthos,et al.  The therapeutic applications of multipotential mesenchymal/stromal stem cells in skeletal tissue repair , 2009, Journal of cellular physiology.

[9]  P. Robbins,et al.  Orthopedic gene therapy in 2008. , 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

[10]  Ivo Pitanguy,et al.  Tissue Engineering in Plastic Surgery: An Up-to-Date Review of the Current Literature , 2009, Annals of plastic surgery.

[11]  M. Kassem,et al.  The use of mesenchymal (skeletal) stem cells for treatment of degenerative diseases: Current status and future perspectives , 2009, Journal of cellular physiology.

[12]  J. Jansen,et al.  The kinetic and biological activity of different loaded rhBMP-2 calcium phosphate cement implants in rats. , 2008, Journal of biomedical materials research. Part A.

[13]  J. Jansen,et al.  Dual delivery of an angiogenic and an osteogenic growth factor for bone regeneration in a critical size defect model. , 2008, Bone.

[14]  C. T. Wagner,et al.  Evaluation criteria for musculoskeletal and craniofacial tissue engineering constructs: a conference report. , 2008, Tissue engineering. Part A.

[15]  S. Badylak,et al.  A perivascular origin for mesenchymal stem cells in multiple human organs. , 2008, Cell stem cell.

[16]  Chad A. Cowan,et al.  A high-efficiency system for the generation and study of human induced pluripotent stem cells. , 2008, Cell stem cell.

[17]  Antonios G Mikos,et al.  In vivo biocompatibility of ultra-short single-walled carbon nanotube/biodegradable polymer nanocomposites for bone tissue engineering. , 2008, Bone.

[18]  Matthew C. Phipps,et al.  The effect of RGD peptides on osseointegration of hydroxyapatite biomaterials. , 2008, Biomaterials.

[19]  P Ducheyne,et al.  Bioactive glass particulate material as a filler for bone lesions. , 2008, Journal of oral rehabilitation.

[20]  A. Mikos,et al.  Modulation of the inflammatory response for enhanced bone tissue regeneration. , 2008, Tissue engineering. Part B, Reviews.

[21]  Jiang Chang,et al.  Reconstruction of calvarial defect of rabbits using porous calcium silicate bioactive ceramics. , 2008, Biomaterials.

[22]  Yi Hong,et al.  Collagen-coated polylactide microcarriers/chitosan hydrogel composite: injectable scaffold for cartilage regeneration. , 2008, Journal of biomedical materials research. Part A.

[23]  G. Pelled,et al.  Nonvirally Engineered Porcine Adipose Tissue‐Derived Stem Cells: Use in Posterior Spinal Fusion , 2008, Stem cells.

[24]  H. Kagami,et al.  Injectable Bone Applied for Ridge Augmentation and Dental Implant Placement: Human Progress Study , 2008, Implant dentistry.

[25]  J. van den Dolder,et al.  Bone response and mechanical strength of rabbit femoral defects filled with injectable CaP cements containing TGF-beta 1 loaded gelatin microparticles. , 2008, Biomaterials.

[26]  Cato T Laurencin,et al.  Tissue engineering of bone: material and matrix considerations. , 2008, The Journal of bone and joint surgery. American volume.

[27]  C. V. van Blitterswijk,et al.  Integrating novel technologies to fabricate smart scaffolds , 2008, Journal of biomaterials science. Polymer edition.

[28]  R. Quigg,et al.  TP508 accelerates fracture repair by promoting cell growth over cell death. , 2007, Biochemical and biophysical research communications.

[29]  T. Moilanen,et al.  Non-steroidal anti-inflammatory drugs, cyclooxygenase-2 and the bone healing process. , 2007, Basic & clinical pharmacology & toxicology.

[30]  Paolo Giannoni,et al.  A tissue engineering approach to bone repair in large animal models and in clinical practice. , 2007, Biomaterials.

[31]  C James Kirkpatrick,et al.  Tissue-like self-assembly in cocultures of endothelial cells and osteoblasts and the formation of microcapillary-like structures on three-dimensional porous biomaterials. , 2007, Biomaterials.

[32]  A. Vaccaro,et al.  Clinical applications of BMP-7/OP-1 in fractures, nonunions and spinal fusion , 2007, International Orthopaedics.

[33]  Ulrich Kneser,et al.  Axial prevascularization of porous matrices using an arteriovenous loop promotes survival and differentiation of transplanted autologous osteoblasts. , 2007, Tissue engineering.

[34]  David J Mooney,et al.  Quantitative assessment of scaffold and growth factor‐mediated repair of critically sized bone defects , 2007, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[35]  M. Bouxsein,et al.  Delayed administration of adenoviral BMP-2 vector improves the formation of bone in osseous defects , 2007, Gene Therapy.

[36]  Maurilio Marcacci,et al.  Stem cells associated with macroporous bioceramics for long bone repair: 6- to 7-year outcome of a pilot clinical study. , 2007, Tissue engineering.

[37]  Benjamin Wu,et al.  MicroCT evaluation of three-dimensional mineralization in response to BMP-2 doses in vitro and in critical sized rat calvarial defects. , 2007, Tissue engineering.

[38]  M. Kay,et al.  Sarcoma Derived from Cultured Mesenchymal Stem Cells , 2007, Stem cells.

[39]  Bin Wang,et al.  Homogeneous osteogenesis and bone regeneration by demineralized bone matrix loading with collagen-targeting bone morphogenetic protein-2. , 2007, Biomaterials.

[40]  Jeroen Rouwkema,et al.  Endothelial cells assemble into a 3-dimensional prevascular network in a bone tissue engineering construct. , 2006, Tissue engineering.

[41]  E Schneider,et al.  Effect of BMP-2 gene transfer on bone healing in sheep , 2006, Gene Therapy.

[42]  K. Leong,et al.  In Vivo Evaluation of Plasmid DNA Encoding OP-1 Protein for Spine Fusion , 2006, Spine.

[43]  A. Wetterwald,et al.  Tumor necrosis factor-alpha: alternative role as an inhibitor of osteoclast formation in vitro. , 2006, Bone.

[44]  Joseph A. Buckwalter,et al.  Orthopaedic Basic Science , 2006 .

[45]  S. Bidic,et al.  rhBMP-2 delivered in a calcium phosphate cement accelerates bridging of critical-sized defects in rabbit radii. , 2006, The Journal of bone and joint surgery. American volume.

[46]  P. Bianco,et al.  The use of adult stem cells in rebuilding the human face. , 2006, Journal of the American Dental Association.

[47]  M. Mastrogiacomo,et al.  Reconstruction of extensive long bone defects in sheep using resorbable bioceramics based on silicon stabilized tricalcium phosphate. , 2006, Tissue engineering.

[48]  David J Mooney,et al.  Coating of VEGF-releasing scaffolds with bioactive glass for angiogenesis and bone regeneration. , 2006, Biomaterials.

[49]  A. Boccaccini,et al.  Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering. , 2006, Biomaterials.

[50]  Stefan Wolfart,et al.  Man as living bioreactor: fate of an exogenously prepared customized tissue-engineered mandible. , 2006, Biomaterials.

[51]  Elizabeth L. Hedberg-Dirk,et al.  Porous poly(DL-lactic-co-glycolic acid)/calcium phosphate cement composite for reconstruction of bone defects. , 2006, Tissue engineering.

[52]  M. McGuire,et al.  Application of periodontal tissue engineering using enamel matrix derivative and a human fibroblast-derived dermal substitute to stimulate periodontal wound healing in Class III furcation defects. , 2006, Journal of periodontology.

[53]  C. Tarabusi,et al.  Evaluation of bone healing enhancement by lyophilized bone grafts supplemented with platelet gel: a standardized methodology in patients with tibial osteotomy for genu varus. , 2006, Journal of biomedical materials research. Part B, Applied biomaterials.

[54]  Christina Eckhardt,et al.  Vascular Endothelial Growth Factor Gene‐Activated Matrix (VEGF165‐GAM) Enhances Osteogenesis and Angiogenesis in Large Segmental Bone Defects , 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[55]  Ulrich Joos,et al.  VEGF-activated angiogenesis during bone regeneration. , 2005, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[56]  P. Hernigou,et al.  The use of percutaneous autologous bone marrow transplantation in nonunion and avascular necrosis of bone. , 2005, The Journal of bone and joint surgery. British volume.

[57]  Xuanyong Liu,et al.  In vivo evaluation of plasma-sprayed wollastonite coating. , 2005, Biomaterials.

[58]  C. D. Reyes,et al.  Bio-adhesive Surfaces to Promote Osteoblast Differentiation and Bone Formation , 2005, Journal of dental research.

[59]  J. Jansen,et al.  Effect of varied release kinetics of the osteogenic thrombin peptide TP508 from biodegradable, polymeric scaffolds on bone formation in vivo. , 2005, Journal of biomedical materials research. Part A.

[60]  V. Sikavitsas,et al.  Effect of bone extracellular matrix synthesized in vitro on the osteoblastic differentiation of marrow stromal cells. , 2005, Biomaterials.

[61]  Hiromu Ito,et al.  Remodeling of cortical bone allografts mediated by adherent rAAV-RANKL and VEGF gene therapy , 2005, Nature Medicine.

[62]  Per Aspenberg,et al.  Drugs and fracture repair , 2005, Acta orthopaedica.

[63]  J. Glowacki,et al.  Biomaterials in cartilage and bone tissue engineering , 2004 .

[64]  Georgina E. Milroy,et al.  The effects of molecular weight and porosity on the degradation and drug release from polyglycolide. , 2004, International journal of pharmaceutics.

[65]  Minoru Ueda,et al.  Autogenous injectable bone for regeneration with mesenchymal stem cells and platelet-rich plasma: tissue-engineered bone regeneration. , 2004, Tissue engineering.

[66]  D J Mooney,et al.  Bone Regeneration via a Mineral Substrate and Induced Angiogenesis , 2004, Journal of dental research.

[67]  Antonios G. Mikos,et al.  Mineralized matrix deposition by marrow stromal osteoblasts in 3D perfusion culture increases with increasing fluid shear forces , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[68]  O. Ringdén,et al.  HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells. , 2003, Experimental hematology.

[69]  J. Szatkowski,et al.  Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs) 1 1 J Bone Joint Surg Am 2003;85A:1544–52 , 2003 .

[70]  S. Vukicevic,et al.  An EP2 receptor-selective prostaglandin E2 agonist induces bone healing , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[71]  Cato T Laurencin,et al.  Three-dimensional, bioactive, biodegradable, polymer-bioactive glass composite scaffolds with improved mechanical properties support collagen synthesis and mineralization of human osteoblast-like cells in vitro. , 2003, Journal of biomedical materials research. Part A.

[72]  D. Kallmes,et al.  Ectopic osteogenesis using adenoviral bone morphogenetic protein (BMP)-4 and BMP-6 gene transfer. , 2002, Molecular therapy : the journal of the American Society of Gene Therapy.

[73]  J. Jansen,et al.  Trabecular bone response to injectable calcium phosphate (Ca-P) cement. , 2002, Journal of biomedical materials research.

[74]  J. Fisher,et al.  Soft and hard tissue response to photocrosslinked poly(propylene fumarate) scaffolds in a rabbit model. , 2002, Journal of biomedical materials research.

[75]  G. Lisignoli,et al.  Osteogenesis of large segmental radius defects enhanced by basic fibroblast growth factor activated bone marrow stromal cells grown on non-woven hyaluronic acid-based polymer scaffold. , 2002, Biomaterials.

[76]  K. Debari,et al.  Porcine enamel matrix derivative enhances trabecular bone regeneration during wound healing of injured rat femur , 2001, The Anatomical record.

[77]  J Glowacki,et al.  Effect of RGD coating on osteocompatibility of PLGA-polymer disks in a rat tibial wound. , 2001, Journal of biomedical materials research.

[78]  J. Glowacki,et al.  Tissue reactions to particles of bone‐substitute materials in intraosseous and heterotopic sites in rats: discrimination of osteoinduction, osteocompatibility, and inflammation , 2001, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[79]  L. Bonassar,et al.  Replacement of an avulsed phalanx with tissue-engineered bone. , 2001, The New England journal of medicine.

[80]  R Cancedda,et al.  Repair of large bone defects with the use of autologous bone marrow stromal cells. , 2001, The New England journal of medicine.

[81]  R Langer,et al.  In vitro and in vivo degradation of porous poly(DL-lactic-co-glycolic acid) foams. , 2000, Biomaterials.

[82]  Antonios G. Mikos,et al.  Formation of highly porous biodegradable scaffolds for tissue engineering , 2000 .

[83]  C. M. Agrawal,et al.  Fundamentals of biomechanics in tissue engineering of bone. , 2000, Tissue engineering.

[84]  H. Oonishi,et al.  Quantitative comparison of bone growth behavior in granules of Bioglass, A-W glass-ceramic, and hydroxyapatite. , 2000, Journal of biomedical materials research.

[85]  Antonios G. Mikos,et al.  Growth Factor Delivery for Tissue Engineering , 2000, Pharmaceutical Research.

[86]  J. Mellonig,et al.  Histologic evaluation of periodontal healing in humans following regenerative therapy with enamel matrix derivative. A 10-case series. , 2000, Journal of periodontology.

[87]  J. Izquierdo,et al.  Plant biotechnology and food security in Latin America and the Caribbean , 2000 .

[88]  S. Takahashi,et al.  A synthetic porous ceramic as a bone graft substitute in the surgical management of scoliosis: a prospective, randomized study. , 2000, Spine.

[89]  Stephen E. Feinberg,et al.  An image-based approach for designing and manufacturing craniofacial scaffolds. , 2000, International journal of oral and maxillofacial surgery.

[90]  J Glowacki,et al.  Medium Perfusion Enhances Osteogenesis by Murine Osteosarcoma Cells in Three‐Dimensional Collagen Sponges , 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[91]  Jeffrey Bonadio,et al.  Localized, direct plasmid gene delivery in vivo: prolonged therapy results in reproducible tissue regeneration , 1999, Nature Medicine.

[92]  T. Webster,et al.  Osteoblast adhesion on nanophase ceramics. , 1999, Biomaterials.

[93]  P. Ma,et al.  Porous poly(L-lactic acid)/apatite composites created by biomimetic process. , 1999, Journal of biomedical materials research.

[94]  J E Block,et al.  Clinical utility of demineralized bone matrix for osseous defects, arthrodesis, and reconstruction: impact of processing techniques and study methodology. , 1999, Orthopedics.

[95]  M. Pittenger,et al.  Multilineage potential of adult human mesenchymal stem cells. , 1999, Science.

[96]  Darwin J. Prockop,et al.  Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta , 1999, Nature Medicine.

[97]  R. Bizios,et al.  Osteoblast population migration characteristics on substrates modified with immobilized adhesive peptides. , 1999, Biomaterials.

[98]  J. Wozney,et al.  Recombinant human bone morphogenetic protein-2 and collagen for bone regeneration. , 1998, Journal of biomedical materials research.

[99]  A. Mikos,et al.  In vivo degradation of a poly(propylene fumarate)/beta-tricalcium phosphate injectable composite scaffold. , 1998, Journal of biomedical materials research.

[100]  R. Bizios,et al.  Design and function of novel osteoblast-adhesive peptides for chemical modification of biomaterials. , 1998, Journal of biomedical materials research.

[101]  J. Wozney,et al.  Bone Formation with Use of rhBMP-2 (Recombinant Human Bone Morphogenetic Protein-2)* , 1997, The Journal of bone and joint surgery. American volume.

[102]  D. Benayahu,et al.  Single‐Colony Derived Strains of Human Marrow Stromal Fibroblasts Form Bone After Transplantation In Vivo , 1997, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[103]  D. Carnes,et al.  Ability of commercial demineralized freeze-dried bone allograft to induce new bone formation. , 1996, Journal of periodontology.

[104]  S. Goldstein,et al.  Stimulation of new bone formation by direct transfer of osteogenic plasmid genes. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[105]  S D Cook,et al.  Effect of recombinant human osteogenic protein-1 on healing of segmental defects in non-human primates. , 1995, The Journal of bone and joint surgery. American volume.

[106]  D. Davy,et al.  The effect of osteogenin (a bone morphogenetic protein) on the formation of bone in orthotopic segmental defects in rats. , 1994, The Journal of bone and joint surgery. American volume.

[107]  J. Hollinger,et al.  Recombinant human bone morphogenetic protein-2 is superior to demineralized bone matrix in repairing craniotomy defects in rats. , 1994, Journal of biomedical materials research.

[108]  A. Reddi.  Bone and cartilage differentiation. , 1994, Current opinion in genetics & development.

[109]  W C Hayes,et al.  Healing of large segmental defects in rat femurs is aided by RhBMP-2 in PLGA matrix. , 1994, Journal of biomedical materials research.

[110]  D. Ingber,et al.  Prevascularization of porous biodegradable polymers , 1993, Biotechnology and bioengineering.

[111]  V. Goldberg,et al.  The origin of bone formed in composite grafts of porous calcium phosphate ceramic loaded with marrow cells. , 1991, Clinical orthopaedics and related research.

[112]  D Buser,et al.  Influence of surface characteristics on bone integration of titanium implants. A histomorphometric study in miniature pigs. , 1991, Journal of biomedical materials research.

[113]  Musculoskeletal,et al.  Bone and Cartilage Allografts: Biology and Clinical Applications , 1991 .

[114]  J. Connolly,et al.  Autologous Marrow Injection for Delayed Unions of the Tibia: A Preliminary Report , 1989, Journal of orthopaedic trauma.

[115]  Fred H. Linthicum,et al.  Tissue reaction to prosthetic materials in human temporal bones. , 1983, The American journal of otology.

[116]  H. Burchardt.  The biology of bone graft repair. , 1983, Clinical orthopaedics and related research.

[117]  J. Glowacki,et al.  Induced Osteogenesis for Repair and Construction in the Craniofacial Region , 1980, Plastic and reconstructive surgery.

[118]  S F Hulbert,et al.  Potential of ceramic materials as permanently implantable skeletal prostheses. , 1970, Journal of biomedical materials research.

[119]  A. Friedenstein,et al.  Osteogenesis in transplants of bone marrow cells. , 1966, Journal of embryology and experimental morphology.

[120]  G. Hastings,et al.  Handbook of Biomaterial Properties , 2016 .

[121]  Francesca De Crescenzio,et al.  CAD/CAM and rapid prototyped scaffold construction for bone regenerative medicine and surgical transfer of virtual planning: A pilot study , 2009, Comput. Medical Imaging Graph..

[122]  R. Cancedda,et al.  Development of sarcomas in mice implanted with mesenchymal stem cells seeded onto bioscaffolds. , 2009, Carcinogenesis.

[123]  Qiang Zhao,et al.  Enhancement of mesenchymal stem cell attachment to decellularized porcine aortic valve scaffold by in vitro coating with antibody against CD90: a preliminary study on antibody-modified tissue-engineered heart valve. , 2009, Tissue engineering. Part A.

[124]  F. Guilak,et al.  Adipose-derived adult stem cells: isolation, characterization, and differentiation potential. , 2003, Cytotherapy.

[125]  K E Healy,et al.  Biomimetic Peptide Surfaces That Regulate Adhesion, Spreading, Cytoskeletal Organization, and Mineralization of the Matrix Deposited by Osteoblast‐like Cells , 1999, Biotechnology progress.

[126]  P Ducheyne,et al.  Bioactive glass fiber/polymeric composites bond to bone tissue. , 1998, Journal of biomedical materials research.

[127]  G. Daculsi,et al.  Macroporous biphasic calcium phosphate ceramics: influence of macropore diameter and macroporosity percentage on bone ingrowth. , 1998, Biomaterials.

[128]  C T Laurencin,et al.  Three-dimensional degradable porous polymer-ceramic matrices for use in bone repair. , 1996, Journal of biomaterials science. Polymer edition.

[129]  J M Powers,et al.  Fabrication of biodegradable polymer scaffolds to engineer trabecular bone. , 1995, Journal of biomaterials science. Polymer edition.

[130]  R. Langer,et al.  Biodegradable polymers as drug delivery systems , 1990 .

[131]  J. Lewin-Epstein.  Polyvinyl sponge (ivalon) as a scaffold for bone. , 1964, The British journal of oral surgery.