Incidence of schizophrenia and other psychoses in ethnic minority groups: results from the MRC AESOP Study

Background. The incidence of schizophrenia in the African-Caribbean population in England is reported to be raised. We sought to clarify whether (a) the rates of other psychotic disorders are increased, (b) whether psychosis is increased in other ethnic minority groups, and (c) whether particular age or gender groups are especially at risk. Method. We identified all people (n=568) aged 16–64 years presenting to secondary services with their first psychotic symptoms in three well-defined English areas (over a 2-year period in Southeast London and Nottingham and a 9-month period in Bristol). Standardized incidence rates and incidence rate ratios (IRR) for all major psychosis syndromes for all main ethnic groups were calculated. Results. We found remarkably high IRRs for both schizophrenia and manic psychosis in both African-Caribbeans (schizophrenia 9·1, manic psychosis 8·0) and Black Africans (schizophrenia 5·8, manic psychosis 6·2) in men and women. IRRs in other ethnic minority groups were modestly increased as were rates for depressive psychosis and other psychoses in all minority groups. These raised rates were evident in all age groups in our study. Conclusions. Ethnic minority groups are at increased risk for all psychotic illnesses but African-Caribbeans and Black Africans appear to be at especially high risk for both schizophrenia and mania. These findings suggest that (a) either additional risk factors are operating in African-Caribbeans and Black Africans or that these factors are particularly prevalent in these groups, and that (b) such factors increase risk for schizophrenia and mania in these groups.

[1]  Paola Dazzan,et al.  Heterogeneity in incidence rates of schizophrenia and other psychotic syndromes: findings from the 3-center AeSOP study. , 2006, Archives of general psychiatry.

[2]  Incidenceof Schizophreniain Trinidad First-Contact Incidence Rates of Schizophrenia in Trinidad and One-Year Follow-up , 2006 .

[3]  B. Erens,et al.  Psychotic symptoms in the general population of England , 2005, Social Psychiatry and Psychiatric Epidemiology.

[4]  Peter B. Jones,et al.  Incidence of bipolar affective disorder in three UK cities , 2005, British Journal of Psychiatry.

[5]  E. Cantor-Graae,et al.  Schizophrenia and migration: a meta-analysis and review. , 2005, The American journal of psychiatry.

[6]  T. Brugha,et al.  Risk factors and the prevalence of neurosis and psychosis in ethnic groups in Great Britain , 2004, Social Psychiatry and Psychiatric Epidemiology.

[7]  Sukanta Saha,et al.  A systematic review of the incidence of schizophrenia: the distribution of rates and the influence of sex, urbanicity, migrant status and methodology , 2004, BMC medicine.

[8]  T. Silverstone,et al.  The incidence of mania in two areas in the United Kingdom , 1993, Social Psychiatry and Psychiatric Epidemiology.

[9]  J. Hurry,et al.  Psychiatric disorders in selected immigrant groups in Camberwell , 1981, Social psychiatry.

[10]  J. Os,et al.  First admissions for mood disorders in immigrants to the Netherlands , 2003, Social Psychiatry and Psychiatric Epidemiology.

[11]  Richard Pereira The Census Coverage Survey--the key element of a one number census. , 2002, Population trends.

[12]  S. Reeves,et al.  Increased first-contact rates for very-late-onset schizophrenia-like psychosis in African— and Caribbean-born elders , 2001, British Journal of Psychiatry.

[13]  E. Cantor-Graae,et al.  Increased rates of psychosis among immigrants to Sweden: is migration a risk factor for psychosis ? , 2001, Psychological Medicine.

[14]  H. Hoek,et al.  Incidence of psychotic disorders in immigrant groups to The Netherlands. , 2001, The British journal of psychiatry : the journal of mental science.

[15]  R. Murray,et al.  A Jamaican psychiatrist evaluates diagnoses at a London psychiatric hospital , 1999, British Journal of Psychiatry.

[16]  D. Bhugra,et al.  First-contact incidence rate of schizophrenia on Barbados , 1999, British Journal of Psychiatry.

[17]  S. Fernando To the Editor: Studies into issues of 'race' and culture in psychiatry carry far reaching social implications and so the methodology used in them, as well as their presentation in journals, should be approached with caution and sensitivity. , 1998, Psychological Medicine.

[18]  S. Fernando Studies into issues of 'race' and culture in psychiatry. , 1998, Psychological medicine.

[19]  J. Slaets,et al.  Schizophrenia in Surinamese and Dutch Antillean immigrants to The Netherlands: evidence of an increased incidence , 1997, Psychological Medicine.

[20]  P. Jones,et al.  Increased incidence of psychotic disorders in migrants from the Caribbean to the United Kingdom , 1997, Psychological Medicine.

[21]  E. Cantor-Graae,et al.  Increased rates of schizophrenia among immigrants: some methodological concerns raised by Danish findings , 1997, Psychological Medicine.

[22]  G. Der,et al.  Incidence and outcome of schizophrenia in Whites, African-Caribbeans and Asians in London , 1997, Psychological Medicine.

[23]  R. Murray,et al.  Psychotic illness in ethnic minorities: clarification from the 1991 census , 1996, Psychological Medicine.

[24]  F. Hickling,et al.  The Incidence of First Contact Schizophrenia in Jamaica , 1994, British Journal of Psychiatry.

[25]  E. Johnson-Sabine,et al.  Incidence of psychotic illness in London: comparison of ethnic groups , 1994, BMJ.

[26]  A. Korten,et al.  Schizophrenia: manifestations, incidence and course in different cultures. A World Health Organization ten-country study. , 1992, Psychological medicine. Monograph supplement.

[27]  R. Murray,et al.  Schizophrenia and Afro-Caribbeans a Case-Control Study , 1991, British Journal of Psychiatry.

[28]  G. Lewis,et al.  Are British Psychiatrists Racist? , 1990, British Journal of Psychiatry.

[29]  T. Brugha,et al.  SCAN. Schedules for Clinical Assessment in Neuropsychiatry. , 1990, Archives of general psychiatry.

[30]  G. Harrison Searching for the causes of schizophrenia: the role of migrant studies. , 1990, Schizophrenia bulletin.

[31]  A. Bertelsen,et al.  A Cross-National Epidemiological Study of Mania , 1976, British Journal of Psychiatry.