Iron addiction: A novel therapeutic target in ovarian cancer
暂无分享,去创建一个
G. Ning | L. Miller | F. McKeon | C. Crum | F. Torti | S. Torti | Xiaohong Wang | N. Dyment | M. Brewer | L. Tesfay | B. Paul | Yusuke Yamamoto | Debargha Basuli | W. Xian | Zhiyong Deng | M. Lynch | P. Hegde
[1] N. Nagarajan,et al. In vitro and in vivo correlates of physiological and neoplastic human Fallopian tube stem cells , 2016, The Journal of pathology.
[2] F. Torti,et al. Iron and cancer: recent insights , 2016, Annals of the New York Academy of Sciences.
[3] B. Stockwell,et al. Ferroptosis: Death by Lipid Peroxidation. , 2016, Trends in cell biology.
[4] Xianquan Zhang,et al. IL6-induced metastasis modulators p-STAT3, MMP-2 and MMP-9 are targets of 3,3′-diindolylmethane in ovarian cancer cells , 2015, Cellular Oncology.
[5] Nupur K. Das,et al. Preferential Iron Trafficking Characterizes Glioblastoma Stem-like Cells. , 2015, Cancer cell.
[6] N. Barker,et al. Ovary and fimbrial stem cells: biology, niche and cancer origins , 2015, Nature Reviews Molecular Cell Biology.
[7] J. George,et al. Efficient molecular subtype classification of high‐grade serous ovarian cancer , 2015, The Journal of pathology.
[8] L. Miller,et al. Hepcidin regulation in prostate and its disruption in prostate cancer. , 2015, Cancer research.
[9] D. Richardson,et al. Novel Thiosemicarbazones Regulate the Signal Transducer and Activator of Transcription 3 (STAT3) Pathway: Inhibition of Constitutive and Interleukin 6–Induced Activation by Iron Depletion , 2015, Molecular Pharmacology.
[10] G. Ning,et al. The PAX2‐null immunophenotype defines multiple lineages with common expression signatures in benign and neoplastic oviductal epithelium , 2014, The Journal of pathology.
[11] C. Landen,et al. Ovarian cancer stem cells: are they real and why are they important? , 2014, Gynecologic oncology.
[12] J. Dietl. Revisiting the pathogenesis of ovarian cancer: the central role of the fallopian tube , 2014, Archives of Gynecology and Obstetrics.
[13] Matthew E. Welsch,et al. Regulation of Ferroptotic Cancer Cell Death by GPX4 , 2014, Cell.
[14] L. Miller,et al. IRP2 regulates breast tumor growth. , 2014, Cancer research.
[15] J. Mao,et al. Quantifying chromogen intensity in immunohistochemistry via reciprocal intensity , 2013 .
[16] R. Kurman. Origin and molecular pathogenesis of ovarian high-grade serous carcinoma. , 2013, Annals of oncology : official journal of the European Society for Medical Oncology.
[17] C. Sander,et al. Evaluating cell lines as tumour models by comparison of genomic profiles , 2013, Nature Communications.
[18] F. Torti,et al. Iron and cancer: more ore to be mined , 2013, Nature Reviews Cancer.
[19] S. H. van der Burg,et al. Interleukin-6/interleukin-6 receptor pathway as a new therapy target in epithelial ovarian cancer. , 2012, Current pharmaceutical design.
[20] T. Ganz,et al. Molecular mechanism of hepcidin-mediated ferroportin internalization requires ferroportin lysines, not tyrosines or JAK-STAT. , 2012, Cell metabolism.
[21] John Calvin Reed,et al. Ironing Out Cell Death Mechanisms , 2012, Cell.
[22] M. R. Lamprecht,et al. Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death , 2012, Cell.
[23] Suzy V. Torti,et al. An iron regulatory gene signature predicts outcome in breast cancer. , 2011, Cancer research.
[24] Naveena Singh,et al. Interleukin-6 as a Therapeutic Target in Human Ovarian Cancer , 2011, Clinical Cancer Research.
[25] K. Griffith,et al. Aldehyde dehydrogenase in combination with CD133 defines angiogenic ovarian cancer stem cells that portend poor patient survival. , 2011, Cancer research.
[26] R. Drapkin,et al. Modeling high-grade serous ovarian carcinogenesis from the fallopian tube , 2011, Proceedings of the National Academy of Sciences.
[27] F. Torti,et al. Ironing out cancer. , 2011, Cancer research.
[28] R. Bast,et al. Targeting Aldehyde Dehydrogenase Cancer Stem Cells in Ovarian Cancer , 2010, Molecular Cancer Therapeutics.
[29] E. Lengyel. Ovarian cancer development and metastasis. , 2010, The American journal of pathology.
[30] M. Willingham,et al. Ferroportin and iron regulation in breast cancer progression and prognosis. , 2010, Science translational medicine.
[31] Carlos Caldas,et al. Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary , 2010, The Journal of pathology.
[32] R. Drapkin,et al. Ovarian Cancer Pathogenesis: A Model in Evolution , 2009, Journal of oncology.
[33] I. Shih,et al. Ovarian Low-grade and High-grade Serous Carcinoma: Pathogenesis, Clinicopathologic and Molecular Biologic Features, and Diagnostic Problems , 2009, Advances in anatomic pathology.
[34] A. Ghanate,et al. Snail and Slug Mediate Radioresistance and Chemoresistance by Antagonizing p53‐Mediated Apoptosis and Acquiring a Stem‐Like Phenotype in Ovarian Cancer Cells , 2009, Stem cells.
[35] Robert C. Bast,et al. The biology of ovarian cancer: new opportunities for translation , 2009, Nature Reviews Cancer.
[36] J. Marks,et al. Epigenetic regulation of CD133 and tumorigenicity of CD133+ ovarian cancer cells , 2009, Oncogene.
[37] R. Tothill,et al. Novel Molecular Subtypes of Serous and Endometrioid Ovarian Cancer Linked to Clinical Outcome , 2008, Clinical Cancer Research.
[38] Guangchao Sui,et al. PIASy-Mediated Sumoylation of Yin Yang 1 Depends on Their Interaction but Not the RING Finger , 2007, Molecular and Cellular Biology.
[39] D. Haile,et al. Functional consequences of ferroportin 1 mutations. , 2005, Blood cells, molecules & diseases.
[40] V. Viprakasit,et al. In vitro functional analysis of human ferroportin (FPN) and hemochromatosis-associated FPN mutations. , 2005, Blood.
[41] Jing Wu,et al. Iron-induced interleukin-6 gene expression: possible mediation through the extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways. , 2004, Toxicology.
[42] William C Hahn,et al. Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells. , 2003, Cancer cell.
[43] F. Torti,et al. Regulation of ferritin genes and protein. , 2002, Blood.
[44] K. Hatch,et al. c-myc amplification in ovarian cancer. , 1990, Gynecologic oncology.
[45] A. Malpica,et al. Advances in serous tubal intraepithelial carcinoma: correlation with high grade serous carcinoma and ovarian carcinogenesis. , 2014, International journal of clinical and experimental pathology.
[46] B. Stockwell,et al. The role of iron and reactive oxygen species in cell death. , 2014, Nature chemical biology.
[47] D. Gershenson. The life and times of low-grade serous carcinoma of the ovary. , 2013, American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting.