Accessible magnetic resonance imaging: A review

The role of MRI in diagnostics, prognostics, and discoveries in basic sciences has been well established. However, access to this life‐saving technology is largely restricted to countries in upper‐middle to high‐income groups. In this article, we collate recent global MR scanner density data and group them into six geographical regions based on the WHO classification. We then analyze these data with respect to demographic factors such as population size, life expectancy, the percentage of internet users, and World Bank income grouping. We map these demographic factors to five dimensions or characteristics of accessible MRI, adapting definitions from the healthcare literature. With this background, the study then reviews recent demonstrations of accessible MRI categorized based on main magnetic field strength. We describe demonstrated examples for each of these categories, ranging from ultralow‐field to ultrahigh‐field MRI. Lastly, we review MR methods and associated developments impacting accessible MRI such as increasing/augmenting MR awareness and local expertise, incorporating hardware‐cognizant methods, rapid quantitative imaging, and leveraging innovations from adjacent fields.

[1]  Kaufui Wong,et al.  A Review of Additive Manufacturing , 2012 .

[2]  John Clarke,et al.  Dynamical cancellation of pulse-induced transients in a metallic shielded room for ultra-low-field magnetic resonance imaging , 2015 .

[3]  A. Hussain,et al.  Affordable and accessible Tele-healthcare to rural areas of Pakistan through web and mobile based technologies , 2009, 2009 6th International Symposium on High Capacity Optical Networks and Enabling Technologies (HONET).

[4]  Pierre-Marie Robitaille,et al.  Ultra High Field Magnetic Resonance Imaging: A Historical Perspective , 2006 .

[5]  Yoshimi Anzai,et al.  Value of MRI in medicine: More than just another test? , 2018, Journal of magnetic resonance imaging : JMRI.

[6]  L. Siciliani,et al.  Benchmarking Access to Healthcare in the EU : Report of the Expert Panel of effective ways of investing in Health (EXPH) , 2018 .

[7]  Matthew S Rosen,et al.  Two‐dimensional imaging in a lightweight portable MRI scanner without gradient coils , 2015, Magnetic resonance in medicine.

[8]  P. Babyn,et al.  A Day in the Life of MRI: The Variety and Appropriateness of Exams Being Performed in Canada , 2018, Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes.

[9]  C Fermon,et al.  Very low field magnetic resonance imaging with spintronic sensors. , 2013, The Review of scientific instruments.

[11]  P. Lauterbur,et al.  Image Formation by Induced Local Interactions: Examples Employing Nuclear Magnetic Resonance , 1973, Nature.

[12]  Yuan-Ting Zhang,et al.  Towards Affordable and Accessible Healthcare Systems , 2008 .

[13]  G. Topulos,et al.  3He lung imaging in an open access, very‐low‐field human magnetic resonance imaging system , 2005, Magnetic resonance in medicine.

[14]  Joseph P. Hornak,et al.  The Basics of MRI , 2003, WWW 2003.

[15]  D. Miglioretti,et al.  Rising use of diagnostic medical imaging in a large integrated health system. , 2008, Health affairs.

[16]  F. Servadei,et al.  The Role of Neurosurgery in Countries with Limited Facilities: Facts and Challenges. , 2018, World neurosurgery.

[17]  Maxim Zaitsev,et al.  Reconstruction of MRI data encoded by multiple nonbijective curvilinear magnetic fields , 2012, Magnetic resonance in medicine.

[18]  John C. Fortney,et al.  A Re-conceptualization of Access for 21st Century Healthcare , 2011, Journal of General Internal Medicine.

[19]  K. Sung,et al.  Cardiac balanced steady-state free precession MRI at 0.35 T: a comparison study with 1.5 T. , 2018, Quantitative imaging in medicine and surgery.

[20]  John Clarke,et al.  MRI of the human brain at 130 microtesla , 2013, Proceedings of the National Academy of Sciences.

[21]  Scott B King,et al.  MRI using radiofrequency magnetic field phase gradients , 2010, Magnetic resonance in medicine.

[22]  A. Mosadeghrad,et al.  Healthcare Service Quality: Towards a Broad Definition , 2013, International journal of health care quality assurance.

[23]  Sairam Geethanath,et al.  Pulseq-Graphical Programming Interface: Open source visual environment for prototyping pulse sequences and integrated magnetic resonance imaging algorithm development. , 2018, Magnetic resonance imaging.

[24]  MRI in Clinical Practice , 2006 .

[25]  Marja Verhoef,et al.  Integrative healthcare: arriving at a working definition. , 2004, Alternative therapies in health and medicine.

[26]  Thomas Witzel,et al.  Low-Cost High-Performance MRI , 2015, Scientific Reports.

[27]  Jari Penttilä,et al.  Hybrid ultra‐low‐field MRI and magnetoencephalography system based on a commercial whole‐head neuromagnetometer , 2013, Magnetic resonance in medicine.

[28]  M. Østergaard,et al.  Optimised, low cost, low field dedicated extremity MRI is highly specific and sensitive for synovitis and bone erosions in rheumatoid arthritis wrist and finger joints: comparison with conventional high field MRI and radiography , 2005, Annals of the rheumatic diseases.

[29]  Kellyton dos Santos Brito,et al.  Brazilian government open data: implementation, challenges, and potential opportunities , 2014, dg.o '14.

[30]  Fabiola Martínez Licona,et al.  Imaging Facilities for Basic Medical Units: A Case in the State of Guerrero, Mexico , 2011, Journal of Digital Imaging.

[31]  M. Kawooya Training for Rural Radiology and Imaging in Sub-Saharan Africa: Addressing the Mismatch Between Services and Population , 2012, Journal of clinical imaging science.

[32]  RobeRt Kelley,et al.  WHERE CAN $700 BILLION IN WASTE BE CUT ANNUALLY FROM THE U.S. HEALTHCARE SYSTEM? , 2009 .

[33]  Andrew G Webb,et al.  Magnetic Resonance Technology: Hardware and System Component Design , 2016 .

[34]  Emmanuel M. Kaijuka Uganda demographic and health survey , 1989 .

[35]  Michael Garwood,et al.  In vivo MR imaging with simultaneous RF transmission and reception , 2016, Magnetic resonance in medicine.

[36]  Alan J. Thompson,et al.  Atlas of Multiple Sclerosis 2013: A growing global problem with widespread inequity , 2014, Neurology.

[37]  E. Chekmenev,et al.  High-resolution hyperpolarized in vivo metabolic 13C spectroscopy at low magnetic field (48.7mT) following murine tail-vein injection. , 2017, Journal of magnetic resonance.

[38]  J. Zunt,et al.  Building a network for multicenter, prospective research of central nervous system infections in South America: Process and lessons learned , 2018, eNeurologicalSci.

[39]  J. Duerk,et al.  Magnetic Resonance Fingerprinting , 2013, Nature.

[40]  G. Rubin Costing in Radiology and Health Care: Rationale, Relativity, Rudiments, and Realities. , 2017, Radiology.

[41]  Michelle A. Espy,et al.  Progress Toward a Deployable SQUID-Based Ultra-Low Field MRI System for Anatomical Imaging , 2015, IEEE Transactions on Applied Superconductivity.

[42]  Michelle A. Espy,et al.  Ultra-Low Field Nuclear Magnetic Resonance: A New MRI Regime , 2014 .

[43]  L Leape,et al.  Transforming healthcare: a safety imperative , 2009, Quality and Safety in Health Care.

[44]  Kâmil Uğurbil,et al.  Toward imaging the body at 10.5 tesla , 2017, Magnetic resonance in medicine.

[45]  Gian Luca Romani,et al.  Very Low Field MRI: A fast system compatible with Magnetoencephalography , 2015, 2015 IEEE International Symposium on Medical Measurements and Applications (MeMeA) Proceedings.

[46]  Jeffrey W. Prescott,et al.  Quantitative Imaging Biomarkers: The Application of Advanced Image Processing and Analysis to Clinical and Preclinical Decision Making , 2013, Journal of Digital Imaging.

[47]  Yunhong Shu,et al.  Lightweight, compact, and high‐performance 3T MR system for imaging the brain and extremities , 2018, Magnetic resonance in medicine.

[48]  P. Boyle,et al.  An assessment of the barriers to accessing the Basic Package of Health Services (BPHS) in Afghanistan: was the BPHS a success? , 2016, Globalization and Health.

[49]  Yudong Zhu,et al.  Parallel excitation with an array of transmit coils , 2004, Magnetic resonance in medicine.

[50]  Peter M. Jakob,et al.  Design of a mobile, homogeneous, and efficient electromagnet with a large field of view for neonatal low-field MRI , 2016, Magnetic Resonance Materials in Physics, Biology and Medicine.

[51]  A. Arunachalam,et al.  Enhancing the performance of accelerated MRI through preservation of acquisition SNR: An “aliased” k‐space approach , 2015, Magnetic resonance in medicine.

[52]  Sasa Mutic,et al.  The ViewRay system: magnetic resonance-guided and controlled radiotherapy. , 2014, Seminars in radiation oncology.

[53]  Daniel Paech,et al.  Downfield‐NOE‐suppressed amide‐CEST‐MRI at 7 Tesla provides a unique contrast in human glioblastoma , 2017, Magnetic resonance in medicine.

[54]  Carl A. Michal A low-cost spectrometer for NMR measurements in the Earth's magnetic field , 2010 .

[55]  K. Scheffler,et al.  SQUID-based detection of ultra-low-field multinuclear NMR of substances hyperpolarized using signal amplification by reversible exchange , 2017, Scientific Reports.

[56]  D. Mcintyre,et al.  Exploring the dimensions of access. , 2007 .

[57]  K. Uğurbil,et al.  An Assessment of Current Brain Targets for Deep Brain Stimulation Surgery With Susceptibility-Weighted Imaging at 7 Tesla , 2010, Neurosurgery.

[58]  Erich P Huang,et al.  Metrology Standards for Quantitative Imaging Biomarkers. , 2015, Radiology.

[59]  Cameron T. Nutt,et al.  The human resources for health program in Rwanda--new partnership. , 2013, The New England journal of medicine.

[61]  G. Dechambenoit Access to health care in sub-Saharan Africa , 2016, Surgical neurology international.

[62]  T. Naidich,et al.  Synthetic MRI for Clinical Neuroimaging: Results of the Magnetic Resonance Image Compilation (MAGiC) Prospective, Multicenter, Multireader Trial , 2017, American Journal of Neuroradiology.

[63]  A. Burton Training non-physicians as neurosurgeons in sub-Saharan Africa , 2017, Lancet Neurology.

[64]  J. Hennig,et al.  Molecular MRI in the Earth's Magnetic Field Using Continuous Hyperpolarization of a Biomolecule in Water. , 2016, The journal of physical chemistry. B.

[65]  K. Uğurbil,et al.  Ultrahigh field magnetic resonance imaging and spectroscopy. , 2003, Magnetic resonance imaging.

[66]  R. Goebel,et al.  7T vs. 4T: RF power, homogeneity, and signal‐to‐noise comparison in head images , 2001, Magnetic resonance in medicine.

[67]  S. Mori,et al.  Principles of Diffusion Tensor Imaging and Its Applications to Basic Neuroscience Research , 2006, Neuron.

[68]  Jeffrey A. Fessler,et al.  Image Reconstruction is a New Frontier of Machine Learning , 2018, IEEE Transactions on Medical Imaging.